Doctor insights on:
Causes Of Plasma Cell Leukemia
A malignant hematologic neoplasm that originates in the bone marrow and represents a clonal proliferation of hematopoietic elements belonging to any of the myeloid, lymphoid, erythroid, and megakaryocytic lineages. Of note, other hematologic neoplasms like lymphoma or myeloma may demonstrate a leukemic phase without actually originating in the bone marrow ...Read more
I have been recently diagnosed with plasma cell leukemia. I have been advised to have autologus stem cell transplant. Really beneficial?
The cell cycle: ...is activated in the immature "blast" cells of acute leukemia. This is not so much a defect, as it is also a normal attribute of immature blood cells. A major problem is the lack of maturation of these cells into normal non-dividing blood cells. Various transcription factors are mutated and these may cause increased proliferation. CLL is characterized by decreased apoptosis (cell death). ...Read more
Does high white cell count 15.4 and headaches on and off for 6 weeks always indicate leukemia? Or could there still be other causes?
Absolutely not: You can raise your white count to 20,000 by spending a half hour swimming in cold water. If the cells are normally formed, and the rest of your blood count is reasonable, look around for some other cause; you may not find one. Look for a cause of headaches as well -- it may be as simple as needing new eyeglasses. Good luck. ...Read more
Virus and cancers: There are a lot of different viruses known. Only a few of them linked to devlopment of cancer such as hpv to cervical cancer/head and neck cancer, ebv to hodgkin's lymphoma, nasopharyngeal ca; HIV to kaposi sarcoma, etc. Yes, htlv-1 virus is related to adult t cell leukemia/lymphoma, ebv is also associated with burkitt's lymphoma- which can transform into more severe case- burkitt's leukemia. ...Read moreSee 1 more doctor answer