Doctor insights on:
Causes Of Plasma Cell Dyscrasia
Panicking skin biopsy cd3 failed to reveal significant t cell dyscrasia. Do I have the start of lymphoma?
Can you clarify?: You list varying ANA results, one set of low compliment results, fatty liver, hysteroscopy and biopsy negative for cancer, and a skin biopsy that some pathologist stained up with cd3 for some reason and didn't find lymphoma. Lymphoma announces itself as an obvious mass or obvious symptoms. Why in the world are you panicking? Is this a communication failure with your physician? ...Read more
Different: Thrombocytopenic purpura (ttp) is an acute condition involving destruction of blood components including red cells and platelets and can be life threatening. Blood dyscrasia is a general term referring to a chronic or inherited blood compnent disorder such as hemophilia, leukemia, thalassemia, etc. ...Read moreSee 2 more doctor answers
Yes: It is possible to have malfunction of immunoglobulins or low levels in b cell disorders. A subclass deficiency by itself is usually not clinically significant and does not warrant treatment but if an underlying b cell disorder exists, it should be remedied. ...Read more
Infiltrated plasma cells in scalp can cause sccaring alopecia? Or will the hair grow back after clearning this infiltration?
What happens to the plasma membrane of the red blood cells of humans with liver disease to cause the formation of acanthocytes? Thank you.
Change in lipids: The liver is responsible for general metabolism in the body, and the plasma membrane has a complex collection of lipids that are responsible for its "fluidity" and shape. It is believed that the apolipoproteins are abnormal in liver disease and cause fragility of the rbc membrane causing fragmentation and formation of acanthocytes. See also: http://en.Wikipedia.Org/wiki/acanthocyte. ...Read moreSee 1 more doctor answer
"Many": Myeloma and other plasma cell dyscrasia treatments has evolved from standard cytotoxic approaches (eg mp, vad, hypercvad) to "novel" therapies. Immunomodulatory drugs (imids) - eg thalidomide, lenalolidomide, pomalidomide proteasome inhibitors - eg, bortezomib, carfilzomib, etc other: hsp90 inhibitors, hdaci, b-raf, etc. Over the last few years multiple new drugs have been approved for myeloma. ...Read moreSee 1 more doctor answer
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