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Doctor insights on: Causes Of Pernicious Anaemia

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Dr. Steven Ginsberg
1,239 doctors shared insights

Anemia (Definition)

Anemia refers to any condition where there is a decrease in the red blood cells in the body. There are numerous causes of anemia but they can basically be broken down into 3 categories: decreased production of red blood cells increased destruction of red ...Read more


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I have pernicious anaemia had two injections of vitamin b12 last year which caused me to collapse and cardiac arrest so now they won't give me anythng?

I have pernicious anaemia had two injections of vitamin b12 last year which caused me to collapse and cardiac arrest so now they won't give me anythng?

Pernicious anemia: I do not know what caused the collapse/ cardiac arrest(faint or go to ER?) - which is serious so before taking another form would discuss with doctor and would take the first dose in the doctor's office where you can be monitored. High dose oral supplementation is effective as well, as is sublingual and foods with B12 (liver beef, eggs) f/u/w/ doc http://www.aafp.org/afp/2011/0615/p1425.html ...Read more

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What are the effects of pernicious anaemia?

What are the effects of pernicious anaemia?

Fatigue, and ...: In this condition, vitamin B12 is not absorbed and patients become B12 deficient. Results in anemia (low red cells), fatigue. If anemia is severe, patients could feel short-winded. B12 deficiency itself could also cause numbness, fatigue, and possibly neuropsychiatric symptoms. Treatment with vitamin B12 injections or sublingual treatment could reverse these symptoms. ...Read more

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Which diseases are similar to pernicious anaemia?

Which diseases are similar to pernicious anaemia?

A few: Pernicious anemia is a specific type of anemia caused by vitamin b-12 deficiency. This particular type of anemia is usually described as macrocytic or megaloblastic. Other causes of megaloblastic anemia include folate (folic acid) deficiency, certain genetic conditions, some medications, myelodysplastic syndromes (a form of bone marrow cancer). Consulting your physician or a hematologist is necessary. ...Read more

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How are pernicious anaemia and other types of anaemia different?

How are pernicious anaemia and other types of anaemia different?

Vitamin B12 deficit: Pernicious anemia is a specific type of anemia caused by vitamin B12 deficiency due to multiple possible reasons including: insufficient intake, decreased absorption, impaired utilization. Another common type of anemia is the one caused by iron deficiency. Multiple other causes also exist. ...Read more

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Is pernicious anaemia connected to thyroid problems?

Is pernicious anaemia connected to thyroid problems?

Pernicious anemia: Pernicious anemia is usually caused by an autoimmune disease. Patients with auto immune disease can also get thyroid disease as well. ...Read more

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Expresed as a percentage what are the chances a parent ie the mother with Pernicious Anaemia pass it on to a son?

 Expresed as a percentage what are the chances  a parent ie the mother with Pernicious Anaemia  pass   it on to a son?

Unlikely: PA is most often acquired as an auto immune disease like some forms of arthritis which is not something you can inherit.Those rare forms that are genetic are inherited as autosomal recessives, meaning both parents must pass on the gene for it to be active in the offspring.Giving percentages is not realistic.You either acquire it in life by chance or from both parents who are often unaffected ...Read more

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Does pernicious anaemia have any relation with folic acid deficiency?

Does pernicious anaemia have any relation with folic acid deficiency?

See below: Pernicious anemia, by definition is deficiency of vitamin B12 due to inability to absorb the vitamin. Folate deficiency can produce similar symptoms. It there is a possibility that you are deficient in B12, do not take folic acid alone; you must take B12 along with folic acid. ...Read more