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Doctor insights on: Causes Of Paget S Disease Of Bone

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What is paget's disease of the bone like?

What is paget's disease of the bone like?

Bone disorder: Paget' disease is a localized disorder of bone remodeling that involves excessive bone resorption, followed by increased bone formation. This overactivity followed by compensatory bone cell activity leads to a structurally disorganized mass of bone (woven bone), which is weaker, larger, more vascular, and more susceptible to fracture. It can be seen on x-rays, and can be a cause for bone pain. ...Read more

Bone (Definition)

Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more


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Relation of Paget disease of bone and giant cell tumor is what?

Relation of Paget disease of bone and giant cell tumor is what?

Giant: Cell tumor is a rare complication of paget's disease of bone. ...Read more

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Paget's disease of bone is a type of cancer?

Paget's disease of bone is a type of cancer?

No : Paget's disease is a disorder of abnormal bone remodeling. We all lose and build none everyday. In paget's, there's more building than losing, but in an abnormal structure, which makes the bone unstable and prone to breaking. There is often a lot of blood flow to the areas involved and so it can be red and hot. ...Read more

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What are the symptoms of paget's disease of bone?

What are the symptoms of paget's disease of bone?

Not very much to: Start.Most people who have paget's disease of bone experience no symptoms. When symptoms do occur, the most common complaint is bone pain. Pelvis. Paget's disease of bone in the pelvis can cause hip pain.Skull. An overgrowth of bone in the skull can cause hearing loss or headaches. And others see the link below. ...Read more

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What is Paget disease of the nipple?

What is Paget disease of the nipple?

Cancer: Paget's disease of the breast is a scaly eczema-like skin change usually near or on the nipple, which is a malignant disease and is often associated with an underlying breast cancer. ...Read more

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In a nutshell, what is paget's disease of the bone?

Benign usually: Bone enlarges, can be painful, rarely can lead to malignancy. ...Read more

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What is the manifestation of wilson's disease in female?

What is the manifestation of wilson's disease in female?

Same as in male: Miss it, and the person becomes unable to move normally, then paralyzed. The liver develops cirrhosis and ultimately fails. There's moderate hemolysis and often a Fanconi syndrome of the proximal tubule. ...Read more

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What are the symptoms of paget's disease of breast?

What are the symptoms of paget's disease of breast?

Crusting rash: A typical rash around the nipple or areola. More advanced cases may have a breast mass underneath the nipple or palpable lymph nodes in the armpit. ...Read more

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Dr. Liawaty Ho Dr. Ho
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Is there a cure for osteoporosis coupled with Paget's deasease of the bone?

Dr. Liawaty Ho Dr. Ho
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Is there a cure for osteoporosis coupled with Paget's deasease of the bone?

Unfortunately no: There is no cure for osteoporosis and no cure for paget's disease of the bone. Osteoporosis is part of the aging process, wear and tear- no we have not found any fountain of youth yet. Medication is available to help osteoporosis and paget's disease of the bone- that is intended to help relief bony pain, and for other indication- ie. Abnormal blood test etc. Please discuss w/ your md in detail. ...Read more

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What are the cellular and molecular aspects of Paget's disease of bone ?

The answer: is too extensive for 400 words or less, but try this link: http://www.orthochirurg.com/resources/journals/JAAOS/Volume3/V3N6A4.pdf ...Read more

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What are the symptoms of paget's disease of the nipple?

What are the symptoms of paget's disease of the nipple?

Scaling: Pagets disease of the nipple can be a sign of underlying breast cancer. Early signs are dryness, scaling and itching. The severity of the rash increases with the severity of the underlying disease. ...Read more

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What sort of disease is chondrocalcinosis?

What sort of disease is chondrocalcinosis?

Calcium in cartilage: Chondro means cartilage and calcinosis implies calcium deposition into an atypical area. Chondrocalcinosis is often associated with pseudogout, in which calcium pyrophosphate crystals are deposited into joints, and these may cause pain and inflammation. This is similar to gout, but gout involves urate crystals within the joint. I see chondrocalcinosis most commonly within the knee joint. ...Read more

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What are the symptoms of Paget's disease of the breast?

What are the symptoms of Paget's disease of the breast?

Visible irritation: Pagets disease of breat is a rare form of breast cancer. Symptoms include: -flaky or scaly skin on your nipple -crusty, oozing or hardened skin resembling eczema on the nipple, areola or both -itching -redness -a tingling or burning sensation -straw-colored or bloody nipple discharge -a flattened or turned-in nipple -a lump in the breast -thickening skin on the breast. ...Read more

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What are the symptoms of paget's disease of the nipple on a male?

What are the symptoms of paget's disease of the nipple on a male?

Redness: The symptoms of paget's disease in the male are similar to that in a female. These include nipple skin redness, mild skin scaling and possibly flaking. Most patients that have paget's disease have underlying breast cancer however only 1% of breast cancer is found in men. About half of patients can have a underlying mass that can be felt. ...Read more

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What sort of disease is c.M.L.?

What sort of disease is c.M.L.?

Chronic leukemia: Chronic myelogenous leukemia is a chronic cancer that presents with increased numbers of myeloid cells. Splenomegaly may occur. CML may also transform into a more acute and dangerous leukemia in rare cases. Currently CML is effectively treated with tyrosine kinase inhibitors. These inhibitors put the body into a medical remission, which means that the leukemia is not detectable in the blood. ...Read more

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Dr. Arnold Malerman
42 doctors shared insights

Bone (Definition)

Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more


Dr. Michael Thompson
560 doctors shared insights

Bone Diseases (Definition)

Any disease process that affects the skeletal system. Some can be metabolic, such as osteoporosis; others can be infectious, ...Read more