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Doctor insights on: Causes Of Necrosis

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What can cause nerve necrosis?

What can cause nerve necrosis?

Many concerns: Necrosis is "death" or destruction of a nerve, and this sometimes is necessitated to alleviate pain, by an alcohol injection. If a nerve is cut or transected, or if a nerve cell body dies (apoptosis), from a variety of inflammatory or degenerative causes, recovery is not possible. So, nerve death can occur both in central and peripheral nervous systems. Timely treatment is always best. ...Read more

Necrosis (Definition)

Necrosis is the the death of cells and tissue. In dentistry, root canals are often needed when the pulp tissue inside a ...Read more


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What is it about cold injury that kills the organs? Could I ng term exposure cause organ necrosis and kill the victim?

What is it about cold injury that kills the organs? Could I ng term exposure cause organ necrosis and kill the victim?

GivinTheColdShoulder: Your question is a bit vague. But generally, if tissue is actually frozen (frostbite), water crystals form inside the cells and that messes-up the works. When thawed, the tissue is mush. If you are talking about hypothermia, the colder you get the slower your metabolism to the point that the lack of energy formation overcomes the overall slowness of the metabolic processes and then the cells die. ...Read more

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Could using steriods from chemo cause avascular necrosis?

Could using steriods from chemo cause avascular necrosis?

Yes: This is a known complication of taking steroids, especially if you had to take prolonged courses during your chemo regimen (for acute lymphoblastic leukemia, for example). Depending on the location and extent, treatment ranges from physical therapy and waiting, to some orthopedic surgery procedures. If you are still on steroids, you and your oncologist will have the risk/benefit ratio of stopping. ...Read more

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How high would serum lipase be to cause fat necrosis?

How high would serum lipase be to cause fat necrosis?

No specific level: Fat necrosis can occur when blood lipase is high due to pancreatisis. The the lesion may be intra-abdominal and occasionally in the fat elsewhere in the body. Fat necrosis can occur with normal lipase levels due to trauma to fat tissue. In diabetics, fat necrosis can occur without trauma and without elevated lipase. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more

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Why does steroids cause avascular necrosis?

Why does steroids cause avascular necrosis?

We are not sure: We are not sure but there is a linkage seen whether it may be more related ti the underlying problem for which the steroids are given as treatment in the first place. ...Read more

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Do steriods from chemo cause avascular necrosis?

Do steriods from chemo cause avascular necrosis?

Possibly but others: Although avascular necrosis can be related to corticosteroids it is important to know that there are other causes of avascular necrosis. There is a decrease in blood flow to the area involved. Although corticosteroids can be associated, it depends on dose and time and thus chemo steroids are less likely to be associated. Other causes: alcohol, joint injury and increased pressure ...Read more

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Why is the " corticosteroid administration " can cause " avascular necrosis" ? * i need the mechanism how does the " corticosteroid" work.

Why is the " corticosteroid administration " can cause " avascular necrosis" ?
* i need the mechanism how does the " corticosteroid" work.

Not Known: While it is generally agreed that the key problem in avn is compromised blood flow to the bone, the mechanism by which corticosteroid use contributes to avn is not known. It is important to remember that this is a rare and not a common problem in corticosteroid users. ...Read more

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Does ingrown toenail cause tissue necrosis?

Does ingrown toenail cause tissue necrosis?

Should not: unless you get an infection from a long standing/worsening ingrown nail. get it evaluated by your doctor or a podiatrist (foot doctor) ...Read more

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How does prednisone cause avascular necrosis?

How does prednisone cause avascular necrosis?

Still unknown: Even though there is this very well-established connection between chronic Prednisone use and avascular necrosis, how this occurs remains unclear. Numerous hypotheses abound. Some argue that increased lipids seen with steroids cause vessels to joints to clog, leading to oxygen starvation & bone death. A more popular view is that vessel (venous) walls undergo thickening, leading to poor blood flow. ...Read more

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Why do steroids cause avascular necrosis of the femur head?

Why do steroids cause avascular necrosis of the femur head?

Unknown: No one really knows for sure. However, it has been shown that steroids cause elevation of lipids. In rabbits, steroids cause collections of lipids called an embolism. The emboli caused avascular necrosis of the femoral heads in the studied rabbits. ...Read more

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Does taking weight gaining capsules/tablets continously for two years or so cause avascular necrosis of hips or other joints ? I m having it. Plz say.

Does taking weight gaining capsules/tablets continously for two years or so cause avascular necrosis of hips or other joints ? I m having it. Plz say.

Several causes: Whether your medications are contributing depends on what you are taking, and what conditions you are taking them for. Avascular necrosis (avn) can be caused by trauma, by medications such as prednisone, by chronic alcoholism, and by many illnesses such as lupus or sickle cell anemia. Your doctor can help you determine what may have caused the avn. ...Read more

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Can constant breast binding cause fatty necrosis? I have binded my whole puberty and now I have a lump on upper breast. I'm female, 16

Can constant breast binding cause fatty necrosis? I have binded my whole puberty and now I have a lump on upper breast. I'm female, 16

Wouldn't think so: The common cause of lumps at your age include localized fibro adenomas or generalized fibrocystic changes. I would start with having your doc examine the area. If the exam is inconclusive an ultrasound of the breast usually points to the cause. ...Read more

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Does Flonase nasal spray cause avascular necrosis?

Does Flonase nasal spray cause avascular necrosis?

Probably Not: There is a theoretical concerns that any steroid cause avn. Having said that it would be distinctly unusual, if not un heard of, for normal doses of Flonase to cause avn. ...Read more

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Does chemotherapy cause avascular necrosis? Does having cancer treatments such as chemo or radiation increase my risk of avascular necrosis? .

Does chemotherapy cause avascular necrosis? Does having cancer treatments such as chemo or radiation increase my risk of avascular necrosis?

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Perhaps: Certain chemo and radiation can cause avn. Certain cancers and disease can as well. It is best to discuss this with your oncologist or internist. ...Read more

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Does chemotherapy cause avascular necrosis? Does having cancer treatments such as chemo or radiation increase my risk of avascular necrosis? . .

Possible: Certain therapeutics, although not chemotherapy, that are commonly used in cancer patients can be associated with avascular necrosis (avn). Examples of these agents include: zometa, xgeva (denosumab) and avstin that can be associated with osteonecrosis of the jaw. Dexamethasone and radiation therapy can also cause avn. ...Read more

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Can hemachromotosis cause avascular necrosis of the ankle joint?

Can hemachromotosis cause avascular necrosis of the ankle joint?

Arthritis, not AVN: Hemochromatosis is associated with development of arthritis that can affect multiple joints, but is not generally associated with avascular necrosis. ...Read more

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Can cortisone injections to elbow cause avascular necrosis of elbow? I had 4 injections. Last two to elbow joint

Can cortisone injections to elbow cause avascular necrosis of elbow? I had 4 injections. Last two to elbow joint

Not common: Usually avn of any joint is due 2 oral steroids or im injections on a long term basis, also etoh abuse. The intra articular injections repeatedly into a joint cause permanent damage 2 the articular cartilage of the joint. ...Read more

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Can brown recluse spider venom cause avascular necrosis of the hip the bite was 5 inches above the knee the hip pain began 1 month after spider bite ?

Can brown recluse spider venom cause avascular necrosis of the hip the bite was 5 inches above the knee the hip pain began 1 month after spider bite ?

Not likely!: There are no associated reports of this linkage. Both are not uncommon and coincidently may occur together. Avascular necrosis is a severe form of arthritis of the hip caused by disruption of the blood supply to the cartilage on top of the hip. Ultimately leading to hip replacement. Stop gap procedures are in my opinion, ineffectual. ...Read more

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