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Doctor insights on: Causes Of Narcolepsy

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Which part of the brain causes narcolepsy?

Which part of the brain causes narcolepsy?

Hypothalamus: The part of the brain known as the hypothalamus is responsible for narcolepsy. Lack of a neurotransmitter called hypocretin (orexin) in this part of the brain results in the illness. ...Read more

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Dr. Michelle Zetoony
274 doctors shared insights

Narcolepsy (Definition)

Narcolepsy is a condition characterized by extreme sleepiness every few hours during the day and frequent, unexpected sleep attacks. This sleep disorder is believed to be caused by a decrease in a protein in the brain. There is no cure for narcolepsy, but its ...Read more


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Can zoloft (sertraline) cause narcolepsy? I've been taking it for awhile but recently have had day sleeping. Falling asleep for few secs repeatedly.

Can zoloft (sertraline) cause narcolepsy? I've been taking it for awhile but recently have had day sleeping. Falling asleep for few secs repeatedly.

Sleepiness: Zoloft (sertraline) is unlikely to cause sleepiness. You should evaluate your sleep habits and maintain a regular sleep pattern. Make a virtual apt to discuss your condition in detail in the mean time follow sleep hygiene protocols.I hope that was helpful. ...Read more

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Can depression cause sudden bouts of narcolepsy? Can one be depressed without even "feeling/knowing" it?

Can depression cause sudden bouts of narcolepsy?  Can one be depressed without even "feeling/knowing" it?

No and maybe: Read about Narcolepsy and causes: https://en.wikipedia.org/wiki/Narcolepsy A person can have both, but it's not a cause. Denial for reasons like stigma, etc can make one fail to see their depression, but most adults probably will admit to some awareness. Perhaps not. Knowing the range of symptoms can help - irritability , fatigue, etc. Seek a good psych eval and ask ?s. Best! ...Read more

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What could cause weird neurological symptoms with narcolepsy?

Hypocretin: in narcolepsy, many individuals have a loss of hypocretin producing cells. This loss of hypocretin may contribute to some of the neurological symptoms seen in narcolepsy. ...Read more

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Can narcolepsy cause brain cells to die?

Other way around: Actually, narcolepsy is caused by the death of brain cells, not the other way around. Some cells in the hypothalamus produce a chemical called orexin or hypocretin; this chemical in needed for normal sleep/wake cycles. In narcolepsy, these cells are destroyed by your own body (autoimmune), resulting in the loss of the chemical. Presently, there is no way to directly replace the chemical. ...Read more

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Does narcolepsy cause depression? If so how? I have narcolepsy and I am hardly ever depressed?

Does narcolepsy cause depression? If so how? I have narcolepsy and I am hardly ever depressed?

Yes and No: Some people with narcolepsy are upset or they become depressed because falling asleep causes them problems in school or at work. Not everyone has this however, and a person with narcolepsy should not have symptoms of depression, as a rule. It sounds like you are doing well. Keep up the good work! ...Read more

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Since I have a friend with narcolepsy. I became curious of you finally finding the cause. Knowing the cause, you can cure it permanently soon?

Since I have a friend with narcolepsy. I became curious of you finally finding the cause. Knowing the cause, you can cure it permanently soon?

There is no cure: for narcolepsy. The narcolepsy may be due to a deficiency in the production of Orexin. Once it appears, narcolepsy is present for life. The effective management of narcolepsy involves three specific strategies: 1. Pharmacological treatment. 2. Lifestyle adjustments. 3. Alternative medicine. ...Read more

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Some reports say narcoleptic a have problems with memory, thinking, and attention. Does narcolepsy the condition itself cause these?

Not directly: Narcolepsy is a sleep disorder, and the intense episodes of drowsiness interfere with focus and concentration, with secondary cognitive issues which can reverse with effective therapy, such as modafanil, ritalin, (methylphenidate) or Nuvigil. ...Read more

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I have narcolepsy and sometimes i answer questions while im in some type of sleep and don't remember it or vaguely remember also wake up hot. Cause?

I have narcolepsy and sometimes i answer questions while im in some type of sleep and don't remember it or vaguely remember also wake up hot. Cause?

These are normal: Symptoms in narcolepsy.Nighttime wakefulness – if you suffer from narcolepsy, you may have periods of wakefulness at night with hot flashes, elevated heart rate, and sometimes intense alertness. Automatic behavior means that you continues to function (talking, putting things away, etc.) during sleep episodes, but awakens with no memory of performing such activities. Wikipedia and helpguide.Org. Best wishes. ...Read more