Doctor insights on:
Causes Of Muscular Rigidity
Does serotonin cause muscular rigidity via its effects in the central nervous system or by binding to peripheral 5-ht receptors in the body?
Centrally: Overstimulation of primarily the 5-ht2a receptors seems the leading hypothesis currently. ...Read more
If serotonin induced muscular rigidity causes the muscles to contract then are the blood vessels in those muscles also forced to contract?
Will Abilify (aripiprazole) take away some if the muscular rigidity gotten from other ssri medications now stopped bc it is a partial dopa/sero antagonist?
I am not sure the: Ssri has caused muscular rigitity. It likely hasn't helped much, with your level of tissue problems. Consider an snri, like cymbalta, which helps pain and mood. Abilify (aripiprazole) will not cure muscular rigitity. It's mechanism is unlikely to cause more but it could. Do you sleep poorly at night or grind your teeth? If so, needs management. Sleep key to muscular health, Clonazepam 1 mg at bed may help. ...Read more
If you have hyperthermia, muscular rigidity and metabolic acidosis and the only med you are on is an ssri, is this a problem of medications?
Doubt: Doubt it but could another medication have been stopped abruptly? ...Read more
Muscle spasm: Typically if muscles in the cervical and lumbar regions are injured they will go into spasm to protect themselves from further injury this will create the rigidity that the writer describes. The symptoms can be helped with moist heat, muscle relaxants and physical therapy modalities. ...Read more
Meningitis: High fever, severe headache that isn't easily confused with other types of headache, stiff neck, vomiting or nausea with headache, confusion or difficulty concentrating — in the very young, this may appear as inability to maintain eye contact, seizures , sleepiness or difficulty waking up, sensitivity to light, lack of interest in drinking and eating, skin rash in some cases, such as in viral kind. ...Read more