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Doctor insights on: Causes Of Monoclonal Paraproteinemia

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What causes monoclonal paraproteinemia?

What causes monoclonal paraproteinemia?

Excess of Plasma cel: Plasma cells in our bone marrow make antibodies. Sometimes they become overly active/reactive and produce abnormal proteins called paraproteins. Most such protein production is benign and not uncommon in older folks. Sometimes it is excessive(more than 1gram/day) then we get concerned about a condition called multiple myeloma (paraproteins over 3 grams). ...Read more

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Is monoclonal paraproteinemia the same thing as myeloma?

Yes in most ways: Myeloma is one of the differential diagnosis, the other condition is called mgus ...Read more

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What can cause monoclonal gammopathy?

What can cause monoclonal gammopathy?

Mayo Clinic say: Plasma cells are a type of white blood cell. They are found in your bone marrow. Plasma cells produce some of the antibodies that help your body fight infection. Monoclonal gammopathy of undetermined significance occurs when plasma cells in your bone marrow produce an abnormal protein called monoclonal protein (m protein). ...Read more

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What are possible causes of highly elevated ImM levels with low ImG levels with no monoclonal gammopathy present?

What are possible causes of highly elevated ImM levels with low ImG levels with no monoclonal gammopathy present?

May not be a problem: This may depend on your genetic background and not be a medical problem. We would need an explanation of your problems, blurred vision, night sweats. Why are you on opiates ...Read more

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Can monoclonal gammopathy cause osteomyelitis?

Can monoclonal gammopathy cause osteomyelitis?

Not realy: It's estimated that between 10 and 25 percent of people with monoclonal gammopathy of undetermined significance develop a more serious condition, such as multiple myeloma or other cancers or blood disorders. Other complications include fractures and blood clots. ...Read more

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What is monoclonal gammopathy?

A tumor type: There are various grades of monoclonal gammopathy. The three types, in increasing order of malignancy are monoclonal gammapathy of undetermined significance (MGUS), smoldering myeloma and the last one, which is a cancer, multiple myeloma. ...Read more

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What's monoclonal gammopathy of undetermined significance?

MGUS: Is a common precancerous condition affecting people 50 years of age and older. It was first described by mayo clinic researchers in 1978 and is characterized by the presence of an abnormal protein in the blood called a (monoclonal) protein or m protein.Mgus has a small risk (1 percent each year) of progressing to a blood cancer called multiple myeloma or a related condition. ...Read more

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Can i treat a possible monoclonal gammopathy of undetermined significance at home?

Nope: You don't treat an mgus, it is a condition that can ultimately lead to multiple myeloma (risk is about 1% per year) but as of itself does not need therapy (assuming it was correctly diagnosed). You need to have labs checked at least 1 or 2 times a year so you should follow up with your doc indefinitely. ...Read more