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Doctor insights on: Causes Of Monoclonal Gammopathy

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What can cause monoclonal gammopathy?

What can cause monoclonal gammopathy?

Mayo Clinic say: Plasma cells are a type of white blood cell. They are found in your bone marrow. Plasma cells produce some of the antibodies that help your body fight infection. Monoclonal gammopathy of undetermined significance occurs when plasma cells in your bone marrow produce an abnormal protein called monoclonal protein (m protein). ...Read more

Dr. Dariush Saghafi
29 doctors shared insights

Gammopathy (Definition)

A gammopathy is an abnormal gammaglobulin or gammaglobulin level. A monoclonal gammopathy is a single abnormal protein that can indicate a bone marrow cancer called multiple myeloma, or a lymphoma. Further evaluation is required to determine if a monoclonal gammopathy ...Read more


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What are possible causes of highly elevated ImM levels with low ImG levels with no monoclonal gammopathy present?

What are possible causes of highly elevated ImM levels with low ImG levels with no monoclonal gammopathy present?

May not be a problem: This may depend on your genetic background and not be a medical problem. We would need an explanation of your problems, blurred vision, night sweats. Why are you on opiates ...Read more

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Can monoclonal gammopathy cause osteomyelitis?

Can monoclonal gammopathy cause osteomyelitis?

Not realy: It's estimated that between 10 and 25 percent of people with monoclonal gammopathy of undetermined significance develop a more serious condition, such as multiple myeloma or other cancers or blood disorders. Other complications include fractures and blood clots. ...Read more

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What is monoclonal gammopathy?

A tumor type: There are various grades of monoclonal gammopathy. The three types, in increasing order of malignancy are monoclonal gammapathy of undetermined significance (MGUS), smoldering myeloma and the last one, which is a cancer, multiple myeloma. ...Read more

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What's monoclonal gammopathy of undetermined significance?

MGUS: Is a common precancerous condition affecting people 50 years of age and older. It was first described by mayo clinic researchers in 1978 and is characterized by the presence of an abnormal protein in the blood called a (monoclonal) protein or m protein.Mgus has a small risk (1 percent each year) of progressing to a blood cancer called multiple myeloma or a related condition. ...Read more

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Can i treat a possible monoclonal gammopathy of undetermined significance at home?

Nope: You don't treat an mgus, it is a condition that can ultimately lead to multiple myeloma (risk is about 1% per year) but as of itself does not need therapy (assuming it was correctly diagnosed). You need to have labs checked at least 1 or 2 times a year so you should follow up with your doc indefinitely. ...Read more

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Is mononuclueosis associated at all with monoclonal gammopathy?

Is mononuclueosis associated at all with monoclonal gammopathy?

No: Ebv infection, the cause of mononucleosis is not usually related to monoclonal gammopathy. Ebv induced lymphoma may produce monoclonal gammopathy, but that would be an uncommon situation. ...Read more

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What is monoclonal gammopathy of undetermined significance (mgus)?

Blood & urine tests: Mgus is the presence of an abnormal protrein in the blood made by a type of white blood cell called a plasmacyte. In most cases, it is at a low level and is something that just has to be followed. However, it can be the precursor of the disease called multiple myeloma and as such a hematologist or medical oncologist will order tests to rule this out which may include blood, urine and simple x-rays. ...Read more

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