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Doctor insights on: Causes Of Metabolic Acidosis

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Dr. Fred McCurdy
60 doctors shared insights

Metabolic Acidosis (Definition)

Metabolic acidosis occurs either from primary acid retention, renal (kidney) dysfunction/failure or bicarbonate (sodium bicarbonate) losses. Primary acid retentions cause anion-gap metabolic acidosis from these etiologies (methanol, uremia, diabetic ketoacidosis, para-aldehyde, isoniazid, lactic acidosis, ethylene glycol, salicylates). Kidney's dysfunction leads to acidosis. Finally any loss ...Read more


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Can topamax (topiramate) cause metabolic acidosis?

Can topamax (topiramate) cause metabolic acidosis?

Yes: Among the side effects, including cognitive issues, narrow angle glaucoma, heat stroke risk in kids, kidney stones; is also, metabolic acidosis, which can potentially be life threatening. It has been associated with kidney disease, and surgery. It is advised to stop topamax (topiramate) if surgery is planned. ...Read more

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Could use expert help with why a fever causes metabolic acidosis?

Could use expert help with why a fever causes metabolic acidosis?

Doesn't: Fever by itself will not cause a metabolic acidosis. But when associated with sepsis can be due to lactic acidosis, with starvation ketoacidosis. Infections are frequently associated with these conditions very ill patients, this is not your every day fever. ...Read more

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I take KRISTALOSE/Lactulose daily. Can this cause lactic or metabolic acidosis? Are there any recommendations for monitoring?

I take KRISTALOSE/Lactulose daily. Can this cause lactic or metabolic acidosis? Are there any recommendations for monitoring?

No, It is inert: Kristalose, a brand of lactulose, is an indigestible disaccharide for treating constipation. It arrives intact in the large bowel. Bacteria break it down to lactic and formic acid increasing osmotic pressure, drawing in water, softening stool in one to two days due to transit time to the colon. Antacids may inhibit it's effect. In the elderly, it may disrupt electrolyte balance in six months. ...Read more

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Is metformin dangerous with diet-induced(not diabetes-induced)ketosis?Like would a ketogenic diet+metf cause metabolic acidosis?(2000mgmet a day btw)

Is metformin dangerous with diet-induced(not diabetes-induced)ketosis?Like would a ketogenic diet+metf cause metabolic acidosis?(2000mgmet a day btw)

Its possible: I have many patients on metformin and in ketosis and its sometimes fine but you must watch out for hypoglycemia. For example if on a regular diet you require metformin but then then go into ketosis (which will severely reduce your' blood sugar) if you keep taking the same dose of metformin you could become hypoglycemic and this needs to be monitored by your' doctor. ...Read more

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Why does respiratory alkalosis cause hypokalemia while metabolic acidosis causes hyperkalemia?

Potassium shift: the concentration of electrolytes in the body and blood stream are very complex. The body strives to maintain normal concentrations of potassium, acid, as well as electrical charge. Acidosis causes a build up of hydrogen and cells will shift hydrogen and potassium to prevent acid buildup as a result potassium goes up, the reverse occurs when alkalosis happens ...Read more

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How does high chloride cause a (non-anion gap) metabolic acidosis?

See below: Please consult this site for the information. It is more involved than the 400 characters will allow. http://emedicine.medscape.com/article/240809-overview ...Read more

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How can metabolic acidosis cause kussmaul breathing?

How can metabolic acidosis cause kussmaul breathing?

Yes.: Kussmaul breathing is a deep and labored breathing pattern often associated with severe metabolic acidosis, particularly diabetic ketoacidosis (DKA) but also renal failure. It is a form of hyperventilation, which is any breathing pattern that reduces carbon dioxide in the blood due to increased rate or depth of respiration. In metabolic acidosis, breathing is first rapid and shallow. ...Read more

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Could metabolic acidosis be one possible cause of rosacea ?

Could metabolic acidosis be one possible cause of rosacea ?

Not likely: Rosacea is usually caused by or aggravated by Sun or wind exposure, spices, and alcohol but metabolic acidosis is not usually a cause but I don't know whether it would aggravate it. A dermatologist is best qualified to answer your question and treat rosacea. ...Read more

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Acidosis (Definition)

Normally our body chemistry is kept in a narrow range, and in particular the amount of acid in the body is kept within a narrow range. The amount of acid is measured by a value called the ph. It is normally a value between 7.35 and 7.45, values below 7.35 are considered to be "acidotic" a patient with this value of the blood chemistry ...Read more