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Doctor insights on: Causes Of Lymphomatoid Granulomatosis

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Causes of wegeners granulomatosis and treatment?

Causes of wegeners granulomatosis and treatment?

Autoimmune disease: Like all autoimmune diseases, the cause is not really known, but likely a combination of genetic factors and environmental exposures (e.g., infections, chemicals, pollutants). Treatment depends on how severe disease it is. Typically steroids (e.g. Prednisone) and if severe, Cytoxan or rituxan (rituximab). If limited disease (just nasal/upper airway involvement), Methotrexate may be sufficient. ...Read more

Dr. Jeffrey Stevens
44 doctors shared insights

Granulomatosis (Definition)

A process associated with a tissue reacton involving monocytes and tissue macrophages. Clasically this was seen in infections, like tuberculosis and some fungal processes. It is also seen and inflammatory and reactive ...Read more


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Causes of hypergammaglobulinemia?

Causes of hypergammaglobulinemia?

Mono or Polyclonal: High levels of immunoglobulins (hypergammaglobulinemia) can be monoclonal (specific) - due to malignant proliferation of plasma cells or lymphocytes as in myeloma or waldenstrom's macroglobulinemia. Polyclonal (many types) hypergammaglobulinemia is a benign condition due to infection, inflammation causing non-specific gamma globulin production such as in hepatitis, immune and allergic disorders. ...Read more

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Which kind of blood cancer cause idiopathic thrombocytopenia ? Including chronic malignancy

Which kind of blood cancer cause idiopathic thrombocytopenia ? Including chronic  malignancy

By itself: Essential thrombocythemia is a low-grade blood cancer that often requires no treatment. Most unexplained thrombocytosis in people who seem well otherwise is due to iron deficiency. Nobody understands how this works. Hoping you find the answers you need, and glad you asked. ...Read more

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Causes of aniocytosis?

Causes of aniocytosis?

Anisocytosis, having: Red blood cells (rbc's) of different sizes, can be caused by iron deficiency & sickle cell anemias, folate (folic acid) or vitamin B12 deficiency, autoimmune hemolytic anemia, cytotoxic chemotherapy, chronic liver disease, myelodysplastic syndrome, thalassemia major, & thalassemia intermedia. The unequal-sized rbc's are small in some of these disorders & large in others. ...Read more

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What are the causes of hematological malignancies? What is the leading cause for hematological malignancies, such as leukemia or lymphoma?

What are the causes of hematological malignancies? What is the leading cause for hematological malignancies, such as leukemia or lymphoma?

Hard to say...: Many times we don't know what causes leukemia or lymphoma, irrespective of type. The process is probably multifactorial and has a strong genetic component. In a small subset of cases exposure to various toxins like paint fumes, or to radiation, can also cause it, but this represents only a small percentage of patients. There is also an association with certain viruses (ebv, htlv). ...Read more

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What are symptoms of wegener's granulomatosis?

See details: The most common presenting symptom is a chronic sinusitis but there can be numerous other issues associated with wegener's including arthritis, pneumonia, eye problems, kidney disease and cardiac and neurologic issues. ...Read more

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What're the effects of chronic lymphocytic leukemia?

What're the effects of chronic lymphocytic leukemia?

See below: Cll is form of blood cancer, usually a slowly progressing one. It may cause fever, enlarged lymph nodes, weight loss, anemia etc. See this site for more info. http://www.ncbi.nlm.nih.gov/pubmedhealth/pmh0001559/. ...Read more

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What are the symptoms of chronic granulomatous disease?

What are the symptoms of chronic granulomatous disease?

Chronic infections: Chronic granulomatous disease (cgd) is a genetic disorder in which immune system cells are unable to kill some types of bacteria and fungi. The disorder leads to long term (chronic) and repeated (recurrent) infections. The condition is often discovered in very early childhood. Milder forms may be diagnosed at a later age. Check this site. http://www.ncbi.nlm.nih.gov/pubmedhealth/pmh0002219/. ...Read more

Dr. Jay Park Dr. Park
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What sort of disease is chronic granulomatous disease (c.G.D.)?

Dr. Jay Park Dr. Park
2 doctors agreed:

Immunodeficiency: The body's immune system is made of 3 kinds of cells: t-cells, b-cells and WBC (white blood cell). Wbcs roam the various tissues and engulf bacteria and fungi they encounter and then digest them inside themselves. When a crucial molecule, the reactive oxygen species (ros) is not present to enable the killing, the infection is not stopped. So these patients get sick very often. ...Read more

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What are common causes of granulomatous calcifications in the spleen?

What are common causes of granulomatous calcifications in the spleen?

Calcifications: The spleen filters a lot of blood and with that, a multitude of infectious material, since the spleen is part of the immune system. Many causes of calcifications but common ones are old infection, clusters of old cells, injury to the spleen or vascular beds themselves, etc.. ...Read more

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What are the known causes of thymic carcinoma?

What are the known causes of thymic carcinoma?

None are common: The vast majority of thymic carcinomas of all sorts "just happen", without any identifiable risk factors. Genetic mutation is a lottery over the lifetime, and some folks are lucky enough to escape all cancers through old age, but others may end up with an unusual one such as thymic carcinoma. Some of them are very curable while others are tough; i wish you luck. ...Read more

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Causes of chrons disease?

Causes of chrons disease?

Not known yet: The cause seems to be a combination of genetics (different immune defects) and environmental triggers. The subtypes of crohn's disease may also have different immune defects, and for this reason people may respond differently to treatments. Though much more is known now about cd, we still don't know the cause. But stress and some foods can make it worse. Decreasing stressors can help a lot. ...Read more

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What is lymphomatoid granulomatosis?

What is lymphomatoid granulomatosis?

Granulomatosis: It is a lymphoproliferative disorder (lymphomatoid means lymphoma-like). The word granulomatosis denotes one of its microscopic character, polymorphic lymphoid infiltrates and focal necrosis within it. It usually involves lung, skin, and central nervous system. It is caused by the epstein barr virus (same virus causes mono). No proven treatment but research trials are being done at nih. ...Read more

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What sort of disease is chronic lymphocytic leukemia (c.L.L.)?

What sort of disease is chronic lymphocytic leukemia (c.L.L.)?

CLL: Cll is a clonal disorder (cancer) of the white blood cells (specifically lymphocytes) in the blood (= -emia part). Other leukemias include cml, aml, all, etc. Cll is often diagnosed by flow cytometry on peripheral blood. Additional studies may include ct scans and bone marrow biopsy. One staging system is rai 0 to iv. Treatment ranges from observation (rai 0-1) to various tx individualized to pt. ...Read more

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What causes hodgkin's disease?

What causes hodgkin's disease?

Hypothesis: Hodgkins cells are likely derived from germinal center b cells that have undergone mutations in the immunoglobulin variable chain. ...Read more

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What causes hematologic cancers of the blood?

What causes hematologic cancers of the blood?

Chemicals: And viruses. The cause is unknown in most cases. Some chemicals, e.g., benzene and some viruses, e.g., ebv are known to be associated with hematologic cancers. Some of these cancers due to chromosomal alterations, which are usually acquired through unknown causes. ...Read more

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What are causes of primary bone lymphoma?

What are causes of primary bone lymphoma?

Viral: It appears that lymphoma, especially in bone marrow arises from viral transfection of the Wnt-1 gene. This occurs in 3 systems, that is the invasion of the MMTV virus into the cells of the milk duct of the breast, the cells of the prostate and the lymphocyte. The Wnt-1 gene then turns on overexpression of B catenin which leads to the transformation to malignancy. ...Read more