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Doctor insights on: Causes Of Lupus Pernio

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Dr. Alfred Kim Dr. Kim
2 doctors agreed:
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What gene causes lupus erythematosus?

Dr. Alfred Kim Dr. Kim
2 doctors agreed:
What gene causes lupus erythematosus?

Many genes: The previous answer is right with several genes associated with lupus, but no one knows how those genes cause disease. I think it's important to remember that there is likely many ways to develop lupus symptoms, and this will vary between people. So some of these known genes will be important for some, and not important for others. As we sequence more patients, we'll have more answers. ...Read more

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What causes the autoimmune disorder called lupus?

What causes the autoimmune disorder called lupus?

Unknown: Genetic, hormonal, immunologic, and environmental factors may play a role but the overall cause of lupus is unknown. The immune system becomes activated and attacks the body itself hence the term autoimmune. ...Read more

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What are the symptoms of systemic lupus erythematosus?

What are the symptoms of systemic lupus erythematosus?

Many: People with lupus may have joint pain, skin rashes, chest pain, heart probelms, hair loss, fingers changing color in the cold, rash in the sunshine, neuro-psychologic problems. These are only soemof the symtpoms peopel can have. They can also have none of these. Your physician will evaluate all of these, get labs tests and imaging. ...Read more

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Can systemic lupus erythematosus cause swelling in one hand?

Can systemic lupus erythematosus cause swelling in one hand?

Yes: A common symptom of sle is arthritis or joint pain and swelling which can involve just one hand. Usually there will be other symptoms as well such malar rash (red rash over the cheeks), increased sensitivity to sun, possibly hair loss and rash on the body, hands or knuckles or scalp. ...Read more

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What are the associated symptoms of subacute cutaneous lupus?

What are the associated symptoms of subacute cutaneous lupus?

Rash: There are different types of subacute cutaneous lupus (scle) - a characteristic form has lesions that may have an annular configuration, with raised red borders and central clearing. A second type of scle has psoriasis-like lesions with red scaly patches on the arms, shoulders, neck, and trunk and fewer patches on the face. This rash is characteristically made worse by sunshine - photosensitive. ...Read more

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In sjogrens syndrome, sle and subacute cutaneous lupus, is the underlying problem the same?

In sjogrens syndrome, sle and subacute cutaneous lupus, is the underlying problem the same?

Yes: The three conditions all share a common underlying mechanism, that of autoimmune inflammation. Each condition manifests this mechanism in a specific organ or gland, namely the salivary gland, skin, kidneys, etc. ...Read more

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What is the cause of lupus erythematosus?

What is the cause of lupus erythematosus?

Autoimmune: Systemic lupus erythematosus is an auto immune illness. This means people have a immume response against themselves and their own tissues. The hallmark blood test is a positive anti-nuclear antibody or an ana. Depending on what tissue is involved results in the clinical symptoms such as rash, arthritis, kidney disease etc. The cause seems be a combination of genetic and environmental exposures. ...Read more

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Causes of hypergammaglobulinemia?

Causes of hypergammaglobulinemia?

Mono or Polyclonal: High levels of immunoglobulins (hypergammaglobulinemia) can be monoclonal (specific) - due to malignant proliferation of plasma cells or lymphocytes as in myeloma or waldenstrom's macroglobulinemia. Polyclonal (many types) hypergammaglobulinemia is a benign condition due to infection, inflammation causing non-specific gamma globulin production such as in hepatitis, immune and allergic disorders. ...Read more

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Causes of wegeners granulomatosis and treatment?

Causes of wegeners granulomatosis and treatment?

Autoimmune disease: Like all autoimmune diseases, the cause is not really known, but likely a combination of genetic factors and environmental exposures (e.g., infections, chemicals, pollutants). Treatment depends on how severe disease it is. Typically steroids (e.g. Prednisone) and if severe, Cytoxan or rituxan (rituximab). If limited disease (just nasal/upper airway involvement), Methotrexate may be sufficient. ...Read more

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What are the symptoms of lupus and other autoimmune diseases?

Varied symptoms: Each autoimmune disease can present with multiple symptoms.common ones are rashes, joint pains, hair loss, ulcers in the mouth, irregular menstrual cycles, , photosensitivity, joint swelling etc. Usually its constellation of of signs and symptoms that suggest autoimmune disease.Then it is confirmed by blood tests ...Read more

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What is trigger systemic lupus erythematosus in antiquity?

What is trigger systemic lupus erythematosus in antiquity?

Mysterious lupus: It is not known what causes lupus erythematosus. Referring to antiquity, lupus was used to describe several different rashes. It could be autoimmune, where the body attacks itself such as lupus erythematosus or discoid lupus. It could be caused by tuberculosis infection such as lupus vulgaris. It could be related to another inflammatory disease such as sarcoidosis which causes lupus pernio. ...Read more

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What kind of blood/ circulation illness causes livedo reticularis and loss of leg's hair?

What kind of blood/ circulation illness causes livedo reticularis and loss of leg's hair?

Two questions: Two questions.First is livedo reticularis which is pink vascular skin leg disease with net pattern, associated with diseases like lupus, drugs ; dialysis. 2nd is leg hair loss which can be due to pad, drugs, steroids, skin diseases, thyroid problem, alopecia etc . Please see you doctor for history exam and diagnostic tests. Thanks. ...Read more

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Dr. Liawaty Ho Dr. Ho
4 doctors agreed:
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Is systemic lupus erythematosus a kind of cancer?

Dr. Liawaty Ho Dr. Ho
4 doctors agreed:
Is systemic lupus erythematosus a kind of cancer?

No : It is an autoimmune disorder that can affect multiple organs. It is not cancer. ...Read more

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What causes uticarial vasculitis?

What causes uticarial vasculitis?

Autoimmune: This is an autoimmune disease that causes inflammation in the blood vessel walls and eventual urticaria. Treating the underlying disease usually helps in controlling the urticaria. ...Read more

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Causes of chrons disease?

Causes of chrons disease?

Not known yet: The cause seems to be a combination of genetics (different immune defects) and environmental triggers. The subtypes of crohn's disease may also have different immune defects, and for this reason people may respond differently to treatments. Though much more is known now about cd, we still don't know the cause. But stress and some foods can make it worse. Decreasing stressors can help a lot. ...Read more

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What are the causes of raynauds syndrome?

What are the causes of raynauds syndrome?

Usually cold: Raynauds involves cold or stress induced vasospasm of small vessels in hands and feet. It is really more of an annoyance than a harmful problem. Calcium channel blockers are the most common medication that physicians use to treat the symptoms of raynauds. The main drawback is the side effects from these medicines. Keeping your hands and feet warm remains the best treatment. ...Read more

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