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Doctor insights on: Causes Of Low Prothrombin Time

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Dr. Joseph Woods Dr. Woods
Pathology
24 years in practice
State University of New York Upstate Medical University
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What does it mean when my prothrombin time blood test is high, compared to normal or low?

What does it mean when my prothrombin time blood test is high, compared to normal or low?

Can mean Vit K low.: If prothrombin time blood test is high, without other high levels, it can mean a vitamin k deficiency or warfarin use. Vitamin k helps in the function and viability of factors ii, vii, ix, and x and these affect prothrombin time. If there are other levels altered, it could be a factor v, or x deficiency, disseminated intravascular coagulation (dic), or liver failure. See your doctor to be sure.

Dr. Shimae Fitzgibbons
210 Doctors shared insights

Prothrombin Time (Definition)

Prothrombin time provides information regarding the extrinsic pathway involved in clot formation. It's commonly used ...Read more


Dr. Muaiad Kittaneh Dr. Kittaneh
Addiction Medicine
16 years in practice
University of Alberta Faculty of Medicine and Dentistry
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Daughter has high monocytes, eos, eos absolute, platelets and prothrombin time. What can cause this?

Daughter has high monocytes, eos, eos absolute, platelets and prothrombin time. What can cause this?

See a hematologist: There are several differentials to be considered. Only a hematologist (a blood specialist) can guide you on the most appropriate next step to find the cause. Looking at the blood under the microscope and reviewing other blood tests as well as physical exam can narrow down the list. Often times, a bone marrow biopsy may be needed.

Dr. Richard Orr Dr. Orr
Surgery - Oncology
40 years in practice
University of South Florida College of Medicine
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What can cause my daughter to have high monocytes, eos, eos absolute, platelets and prothrombin time?

What can cause my daughter to have high monocytes, eos, eos absolute, platelets and prothrombin time?

Check with doc: Isolated increases in monocytes and eosinophils are often normal, especially if the overall WBC is normal and the patient is not sick. There are many causes for an elevated pro time - typically taking anticoagulants (warfarin, coumadin), some bleeding problems, vit k malabsorption or poor nutrition. If more than 2 seconds above normal have it checked out.

Dr. Azen Jukic Dr. Jukic
Pathology
24 years in practice
University of Zagreb Faculty of Medicine
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Dr. Gurmukh Singh Dr. Singh
Pathology
45 years in practice
University of Pune, Armed Forces Medical College
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What does a prothrombin time measurement do?

Extrinsic pathway of: Clotting. Pt is dependent on levels of multiple coagulation factors, including x, ix vii, v, and ii.

Dr. Steven Eisenberg Dr. Eisenberg
Internal Medicine - Hematology & Oncology
21 years in practice
Philadelphia College of Osteopathic Medicine
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Decrease in prothrombin time can lead to what?

Decrease in prothrombin time can lead to what?

Repeat test.: A shortened clotting time that does not appear to reflect technical error has been associated with an increased risk of thrombosis, recurrent thrombosis, recurrent miscarriage, or bleeding, and may increase the risk of thrombosis associated with other common thrombotic risk factors (eg, factor v leiden, obesity, increased levels of d-dimer).

Dr. Gurmukh Singh Dr. Singh
Pathology
45 years in practice
University of Pune, Armed Forces Medical College
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How can I get a normal range of prothrombin time?

How can I get a normal range of prothrombin time?

12 Seconds, but INR: Normal prothrombin time varies a from lab to lab; the average value is about 12 seconds. To compensate for the variability, the ratio of each lab's normal to the patient value is reported as international normalized ratio (inr) and an inr of 1.0 is normal.

Dr. Nguyen Nguyen Dr. Nguyen
Pediatrics
46 years in practice
UCLA School of Medicine
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What does an abnormal prothrombin time test mean for you?

What does an abnormal prothrombin time test mean for you?

Abnormal clotting: An abnormal prothrombin time means that there is something wrong with your blood's ability to form clots and prevent bleeding. There are many conditions that result in such an abnormality, and you need to have your doctor figure out what the problem is based on other test findings and your symptoms. Sometimes you'll need a hematologist to consult if there is a chance of a serious bleeding problem.

Dr. Leena Varughese Dr. Varughese
Pathology
9 years in practice
Louisiana State University School of Medicine in New Orleans
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What is the definition or description of: prothrombin time?

What is the definition or description of: prothrombin time?

PTT: Prothrombin time provides information regarding the extrinsic pathway involved in clot formation. It's commonly used to monitor warfarin therapy.

Dr. Gurmukh Singh Dr. Singh
Pathology
45 years in practice
University of Pune, Armed Forces Medical College
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My baby was tested for prothrombin time. His value is 16. Ok?

My baby was tested for prothrombin time. His value is 16. Ok?

Depends: Pt of 16 is higher than the normal in most laboratories. However, the value needs to be taken in the context of other issues. Was the baby pre-mature? Is there any abnormal bleeding? Was the baby given vitamin k and pt repeated? It would be prudent to consult your pediatrician.

Dr. Nguyen Nguyen Dr. Nguyen
Pediatrics
46 years in practice
UCLA School of Medicine
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When would a baby of 1-2 months need prothrombin time testing? What are they looking for?

When would a baby of 1-2 months need prothrombin time testing? What are they looking for?

Unexplaind bruises: When a doctor orders prothrombin time and other clotting tests, he/she is probably looking for a bleeding disorder that may explain bruises in a baby that young.

Dr. Gurmukh Singh Dr. Singh
Pathology
45 years in practice
University of Pune, Armed Forces Medical College
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High prothrombin time levels affect bleeding?

High prothrombin time levels affect bleeding?

Yes.: Prothrombin times about three times higher than normal for the particular lab may be a risk for abnormal bleeding.

Dr. Jianhua Luo Dr. Luo
Pathology
35 years in practice
Guangzhou Medical College
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What is thrombocytopenia and how is a prothrombin time test used?

What is thrombocytopenia and how is a prothrombin time test used?

Blood clotting: Thrombocytopenia means low level of blood plateletes. Prothrombin time is a test for extrinsic coagulation pathway that is initiated with factor vii. Vitamin k deficiency or use of Coumadin (warfarin) or liver function deficiency will prolong the prothrombin time, while several blood clotting diseases that affect intrinsic coagulation such as von willibrand or hemophila will not affect prothrombin time.

Dr. Hushang Haghighat Dr. Haghighat
Pediatrics - Hematology & Oncology
years in practice
14

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What can you tell me about thrombocytopenia and prothrombin time test?

What can you tell me about thrombocytopenia and prothrombin time test?

Low platelet: Thrombocytopenia is low platelet and abnormal prothrombin time is secondary to congenital deficiencies of factor V, VII, and X.

Dr. Ew Christensen Dr. Christensen
Family Medicine
24 years in practice
Saint Louis University School of Medicine
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My prothrombin time is 15.7. Will that be a problem if I have major surgery?

My prothrombin time is 15.7. Will that be a problem if I have major surgery?

Prothrombin time: An elevation in the Prothrombin time should be evaluated before you have surgery. There are many possible causes for this and it could pose a risk for you during surgery.

Dr. Gurmukh Singh Dr. Singh
Pathology
45 years in practice
University of Pune, Armed Forces Medical College
16

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What types of drugs an foods interfere with the coagulation test of prothrombin time?

What types of drugs an foods interfere with the coagulation test of prothrombin time?

Depends on: Circumstances. In a normal person, usual drugs and foods do not affect pt measurably. In patients on warfarin, foods both prolong pt, e.g., grapefruit, or shorten it, e.g., green leafy vegetables. Many drugs affect pt, e.g., birth control pills, isoniazid, anti-fungals, antibiotics, and many other drugs metabolized through cytochrome p450 system, and barbiturates and alcohol.

Dr. Joseph Woods Dr. Woods
Pathology
24 years in practice
State University of New York Upstate Medical University
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What is the prothrombin time in a blood test?

What is the prothrombin time in a blood test?

Measures clot factor: This is a test that measures clotting factor activity. All these factors are synthesized in the liver, except factor viii, so this is also a check on the capability of the liver as well. If this is high, it can be from a deficiency or incabability of the factors or a liver failure issue, like cirrhosis, or a vitamin k deficiency from fat malabsorption. This shoud be worked-up dr.'s office.

Dr. Gurmukh Singh Dr. Singh
Pathology
45 years in practice
University of Pune, Armed Forces Medical College
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What does it mean if my prothrombin time blood test is high?

What does it mean if my prothrombin time blood test is high?

Blood clotting: Defective. Prolonged prothrombin time can be due to deficiency of a number of coagulation factors. A common cause it treatment with warfarin/coumdain. Liver disease is an other common reason for prolonged pt. Depending on the prolongation, the person may be at risk of bleeding.

Dr. Gurmukh Singh Dr. Singh
Pathology
45 years in practice
University of Pune, Armed Forces Medical College
19

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Why is prothrombin time prolonged in eosinophilic gastroenteropathy?

Why is prothrombin time prolonged in eosinophilic gastroenteropathy?

Likely vitamin K: Deficiency. An intestinal lesion is likely to be associated with malabsorption may result in deficiency of vitamin k among other nutrients and prolong prothrombin time. However, this is a long shot explanation and you should be investigated to exclude other causes.

Dr. Louis Cooper Dr. Cooper
Pediatrics
44 years in practice
Medical College of Georgia School of Medicine
20

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Would a prothrombin time of 15.7 stop me from being able to donate my kidney?

Would a prothrombin time of 15.7 stop me from being able to donate my kidney?

Maybe: If your prothrombin time is prolonged, is it because of coumadine treatment or underlying liver disease? This question is best directed to your primary Medical Doctor. Good luck.