Doctor insights on:
Causes Of Low Prothrombin Time
Can mean Vit K low.: If prothrombin time blood test is high, without other high levels, it can mean a vitamin k deficiency or warfarin use. Vitamin k helps in the function and viability of factors ii, vii, ix, and x and these affect prothrombin time. If there are other levels altered, it could be a factor v, or x deficiency, disseminated intravascular coagulation (dic), or liver failure. See your doctor to be sure.
Daughter has high monocytes, eos, eos absolute, platelets and prothrombin time. What can cause this?
See a hematologist: There are several differentials to be considered. Only a hematologist (a blood specialist) can guide you on the most appropriate next step to find the cause. Looking at the blood under the microscope and reviewing other blood tests as well as physical exam can narrow down the list. Often times, a bone marrow biopsy may be needed.
What can cause my daughter to have high monocytes, eos, eos absolute, platelets and prothrombin time?
Check with doc: Isolated increases in monocytes and eosinophils are often normal, especially if the overall WBC is normal and the patient is not sick. There are many causes for an elevated pro time - typically taking anticoagulants (warfarin, coumadin), some bleeding problems, vit k malabsorption or poor nutrition. If more than 2 seconds above normal have it checked out.
Repeat test.: A shortened clotting time that does not appear to reflect technical error has been associated with an increased risk of thrombosis, recurrent thrombosis, recurrent miscarriage, or bleeding, and may increase the risk of thrombosis associated with other common thrombotic risk factors (eg, factor v leiden, obesity, increased levels of d-dimer).
Abnormal clotting: An abnormal prothrombin time means that there is something wrong with your blood's ability to form clots and prevent bleeding. There are many conditions that result in such an abnormality, and you need to have your doctor figure out what the problem is based on other test findings and your symptoms. Sometimes you'll need a hematologist to consult if there is a chance of a serious bleeding problem.
Depends: Pt of 16 is higher than the normal in most laboratories. However, the value needs to be taken in the context of other issues. Was the baby pre-mature? Is there any abnormal bleeding? Was the baby given vitamin k and pt repeated? It would be prudent to consult your pediatrician.
Unexplaind bruises: When a doctor orders prothrombin time and other clotting tests, he/she is probably looking for a bleeding disorder that may explain bruises in a baby that young.
Blood clotting: Thrombocytopenia means low level of blood plateletes. Prothrombin time is a test for extrinsic coagulation pathway that is initiated with factor vii. Vitamin k deficiency or use of Coumadin (warfarin) or liver function deficiency will prolong the prothrombin time, while several blood clotting diseases that affect intrinsic coagulation such as von willibrand or hemophila will not affect prothrombin time.
Depends on: Circumstances. In a normal person, usual drugs and foods do not affect pt measurably. In patients on warfarin, foods both prolong pt, e.g., grapefruit, or shorten it, e.g., green leafy vegetables. Many drugs affect pt, e.g., birth control pills, isoniazid, anti-fungals, antibiotics, and many other drugs metabolized through cytochrome p450 system, and barbiturates and alcohol.
Measures clot factor: This is a test that measures clotting factor activity. All these factors are synthesized in the liver, except factor viii, so this is also a check on the capability of the liver as well. If this is high, it can be from a deficiency or incabability of the factors or a liver failure issue, like cirrhosis, or a vitamin k deficiency from fat malabsorption. This shoud be worked-up dr.'s office.
Maybe: If your prothrombin time is prolonged, is it because of coumadine treatment or underlying liver disease? This question is best directed to your primary Medical Doctor. Good luck.
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