Doctor insights on:
Causes Of Hyperreflexia And Clonus
What are the causes for clonus hyperreflexia in both arms and legs. MRI shows no signs of MS or neuron impairment?
MRI only tells: .. part of the story. If you have myoclonus and hyper-reflexia, you must establish a strong relationship with a good neurologist in order to get diagnosed and treated as soon as possible. North of the equator, there are several devastating neurological disorders that cause these symptoms, multiple sclerosis being only one of them. Please get yourself diagnosed quickly. ...Read more
10 year o son diag clonus hyperreflexia mild left hemipareses what could have caused this quick onset neg brain MRI spine MRI mild bulges l4l5s1. Told unrelated. Is there anything else I can do for him other than ot pt? What could have caused this that I
Cerebral palsy: Children can be missed for this diagnosis, especially if its very mild. Not sure if your child had a long or laborous delivery when you had him, but this can deprive the brain of oxygen during the delivery. Many times children recover well afterwards and cerebral palsy is ruled out. It then manifests later in life as the clonus hyperreflexia or an achilles tendon rupture. See a pm;r/neuro doc. ...Read more
I have clonus and hyperreflexia. Also have sjogren's, low B12 but normal MRI of brain and spine. Burning weak arms legs. Can clonus caused by sjogrens?
Sort this out: Both sjogren's and b-12 deficiencies can cause small fiber neuropathy, which can promote limb burning. The weakness could involve large fibres, but the clonus and hyperreflexia may be a sign of upper motor neuron problem within brain or neck, and thus might require imaging studies. A few tests can be useful, such as mri, and skin punch biopsy. Although sjogren's could mimic ms, and cause clonus. ...Read more
I had +babinski +hoffmans +clonus hyperreflexia cant walk heel/toe and fall to the R. MRI of brain was normal so does that mean all is fine, what next?
Further work up: You are describing an exam consistent with some form of spasticity. In addition to an mri of the brain that you had, you need an mri of the cervical spine to look for spinal cord compression and a full neurological evaluation to rule out ALS, both of which can cause the signs and symptoms you are describing. ...Read more
Both of my feet tremor when they are on toes, when I raise my heel. Is this clonus? They are symmetric. I also have hyperreflexia. Mri brain spine normal
Went to dr for clumsiness I had hyperreflexia legs/arms +jaw jerk +hoffman's sign +babinski & clonus. Neuro ordered MRI of brain What is she looking 4?
Broad ddx: There may be a bilateral cortical/subcortical brain disruption and MRI could help identify a potential cause based on the pattern of abnormalities. For ex: adult-onset leukodystrophy would show extensive demyelination of the white matter sparing the periventricular white matter vs MS vs Cerebral Autosomal-Dominant Arteriopathy, and work-up is different for each disease. ...Read more
Most do not:
If spinal cord impinged, however, some problems may occur.
Be seen and discuss re neurologist consult. ...Read more
Is hyperreflexia permanent or temperory, when caused by alcohol withdraws are over? Is this permanent
Temporary: It is a sign of increased Adrenalin and possibly other neurotransmitters that are seen in alcohol withdrawal. Once the withdrawal is over, they go away. If there is some other cause (a brain or spinal cord lesion, or other diseases or medications that can cause it), then it may persist. A neurologist can help figure it out the cause and treatment. ...Read more
Illnesses that affect the cerebellum and corticospinal tract, or the dorsal columns and corticospinal tract can cause these findings.
Stroke is probably the most common, MS is also a possible explanation, there are also others (trauma, infection, neoplastic disease, etc.) ...Read more
Hyperreflexia is increased reflexes. This is an "upper motor neuron" issue, and comes from diseases of the brain such as multiple sclerosis or a stroke. Cervical spine stenois (tightness) can also cause this bilaterally.
Ataxia is incoordination of motor movements. Most commonly this occurs from disease of the cerebellum. These can be acquired (toxins, low b12) and genetic. ...Read more
Here are a few: May see with spinocerebellar degenerations, such a freidrich's ataxia, not unique to find in multiple sclerosis, might see with von hippel lindau syndrome, sometimes occurs with lupus, vasculitis, sjogren's. Occasionally a meningioma at the base of brain can present this way. Some brainstem strokes do this. Might go to wikepedia, or a site such as mayo clinic, as more information in depth there. ...Read more
I heard that immature myelin in toddlers can cause mild ankle clonus, is it true? When does the myelin will get mature?
Maturation: The nervous system matures from top down and inside to outside. Ankle clonus is normal in infants until they begin to walk, which the maturation allows. Persistence after 15-18 mo would be a problem. They first gain a wide grasp with fingers like pincers, but fine motor control of the individual fingers will not come in until well into school age. ...Read more
Physiology: Due to compression of corticospinal pathways, weakness can occur, and inhibition of these areas in the spinal cord allow excitatory responses to supervene, and thence increased reflexes in the legs. Actually, an archaic response to preserve function in motor pathways in case of injury. ...Read more
Every once in a: While this is seen and nothing overly concerning so long as there are no other symptoms. ...Read more
Unilateral hoffman's sign and on the same side have non sustained ankle clonus. What's the cause of this?
Poss c-spine prob: Hoffman's sign is used by clinicians when there is a suspicion of cervical spine pathology possibly pressing on the spinal cord. The sign is more accurate when present bilaterally but can be seen when unilateral. It has also been reported in hyperthyroidism and anxiety states. I hope this helps. Good luck and well wishes. ...Read more