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Doctor insights on: Causes Of Holosystolic Murmur

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Why does a partial or full avsd cause a holosystolic murmur? Is it because associated valve regurgitation? Thanks.

Why does a partial or full avsd cause a holosystolic murmur? Is it because associated valve regurgitation? Thanks.

Typically: Iin an avsd, there will typically be a systolic ejection murmur from increased flow across the pulmonary valve related to pulmonary overcirculation. The vsd shunting will often be low velocity and not produce an audible murmur, so any holosystolic murmur would usually derive from av valve regurgitation, a common problem in this defect. ...Read more

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Dr. Barton Cook
415 doctors shared insights

Heart Murmur (Definition)

A heart murmur is a sound heard by a stethoscope made by the vibration of blood flow. It can be a normal finding in young healthy people, or can represent abnormal leakage (regurgitation) of a valve, valve narrowing (stenosis), or a congenital condition such as an atrial septal defect, a ventricular septal defect, ...Read more


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I have read that only 3 things cause a holosystolic murmur. Tricuspid regurg, mitral regurg, and ventricular septal defect. Are these the only 3?

I have read that only 3 things cause a holosystolic murmur. Tricuspid regurg, mitral regurg, and ventricular septal defect. Are these the only 3?

Essentially: Technically an lv to RA shunt would also generate a holosystolic murmur. In some ways this could be considered a combination of a vsd and tr, although there is actually a distinct entity involving the atrioventricular septum. (also, from a practical standpoint, it can sometimes be difficult to distinguish a long systolic ejection murmur from a holosystolic murmur.). ...Read more

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What disease is caused by holosystolic murmurs?

What disease is caused by holosystolic murmurs?

Murmurs: Holosystolic murmurs are heart sounds associated with insufficiency of the atrioventricular valves and ventricular septal defects. There are other possible holosystolic murmurs but these are the bulk of them. The murmur is purely sound and causes no problem. The physiologic problem causing the sounds is what causes the problem. ...Read more

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What disease is caused by holosystolic murmurs?

What disease is caused by holosystolic murmurs?

Murmurs: Holosystolic murmurs are heart sounds associated with insufficiency of the atrioventricular valves and ventricular septal defects. There are other possible holosystolic murmurs but these are the bulk of them. The murmur is purely sound and causes no problem. The physiologic problem causing the sounds is what causes the problem. ...Read more

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What is a holosystolic murmur?

Holosystolic: A holosystolic murmur starts with the first heart sound and continues through the second heart sound. Typically these are caused by AV valve insufficiency or ventricular septal defects, they can also occur with aortopulmonary shunts. Arteriovenous fistulas have continuous murmurs associated but we call them bruits. ...Read more

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Can a holosystolic murmur be functional- innocent if echocardiogram is normal?

No: Holosystolic murmurs are not normal. If the echocardiogram is read as normal, either you don't have a holosystolic murmur, or the echocardiogram missed the abnormality causing the murmur. If the echocardiogram is truly normal, it is morst likely that you have a systoli ejection murmur, not a holostysolic murmur. Innocent, or normal heart murmurs, are typically systolic ejection murmurs. ...Read more

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What are holosystolic murmurs?

Sounds...: Classically, a vsd results in increased blood flow from left to right ventricle due to pressure differences and results in a holosystolic murmur. This means that the murmur begins with the av valves closing and ends with the aortic/pulmonic valves closing (phase known as systole). ...Read more

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Is it common knowledge among doctors that holosystolic murmurs are always pathological, and never innocent? Or only experts?

It depends....: A holosystolic murmur, by conventional definition, is a murmur that begins at s1 (the first heart sound) and continues until s2 (racepinephrine) (the second heart sound), frequently obscuring the second heart sound. Typically, the loudness (amplitude) of the murmur and the pitch (frequency) of the murmur are unchanged through systole (plateau-shaped.) with this definition, a holostystolic murmur is never normal. ...Read more

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What medications can treat a pansystolic murmur?

What medications can treat a pansystolic murmur?

Murmur: Heart murmur is noise caused by turbulent blood flow in and around the heart. In timing there are systolic, diastolic and continuous murmurs. By cause there are too many to enumerate here. More information is needed to discuss physiology and treatment ...Read more

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What kind of doctor can diagnose a pansystolic murmur?

Any: This just requires a stethoscope and knowledge of what you are listening to. Cardiologists, or heart specialists, would be expected to be more expert at diagnosing cardiac murmurs. ...Read more

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Anybody know anything about ejection systolic murmur causes?

Anybody know anything about ejection systolic murmur causes?

Flow murmur: Ejection systolic murmur usually refers to a benign murmur caused by increased blood flow. In other words, this is a functional murmur and not caused by any valvular pathology. Common causes are increased heart rate, increased adrenergic tone (ie adrenaline), increase blood volume as in a pregnant state. More serious systolic murmurs indicate aortic stenosis, or outflow tract obstruction. ...Read more

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Systolic Murmur over Aorta. What are the causes of this? Are any benign?

Systolic Murmur over Aorta. What are the causes of this? Are any benign?

Systolic murmur: A systolic murmur over the aorta speaks for aortic stenosis which is either , congenital, caused by an infection or by cholesterol plaques. ...Read more

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In an adult, what kind of murmur would an undiagnosed PDA cause?

In an adult, what kind of murmur would an undiagnosed PDA cause?

Continuous: A continuous machinery sounding murmur may be heard just under the left clavicle (collarbone). ...Read more

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What can heart murmurs be caused by?

What can heart murmurs be caused by?

Many things: There are many types of murmurs that sound and behave differently. Commonly it's related to how blood flows through different parts of your heart. ...Read more

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What is the cause of murmur in heart?

Murmur: Murmurs are asymptomatic and easily inducible in most people and are reflective of turbulent blood flow. Sometimes the turbulence indicates organic structural or functional cardiopulmonary conditions requiring formal diagnosis. ...Read more

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Could a heart murmur be a cause for concern?

Could a heart murmur be a cause for concern?

Depends: There are many different types of murmurs, not all are a problem. A good physical may be all that is needed . Other testing such as echocardiograhy can be very helpful. See your doctor. ...Read more

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What causes a systolic murmur with chest pain?

What causes a systolic murmur with chest pain?

Valve stenosis: Common cause is Aortic Valve stenosis. This is secondary to stiffening of the valves that restricts the blood flow from the heart which causes the heart murmur. This can decrease blood output leading to chest pain as a symptom. ...Read more

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What could cause a systolic heart murmur in a child?

What could cause a systolic heart murmur in a child?

Many things: The most common systolic murmur is an innocent flow murmur. Some murmurs represent rapid blood flow through a tight valve or tube, some rapid flow through a whole. Many docs are rained to know based on exam, but a cardiac ultrasound is sometimes done to confirm or exclude the initial impression. ...Read more