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Doctor insights on: Causes Of High Inr Levels

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What is the cause of high INR levels?

What is the cause of high INR levels?

INR: Inr is a measure of clotting involving factors which we block with the drug warfarin. When the inr is high the factors are being blocked and clotting is inhibited. Usually we aim for an inr of 2 to 3 times standard. Sometimes we aim higher. If not on warfarin then the liver may be damaged causing the factors to be low.

Dr. Afshine Emrani
268 Doctors shared insights

Inr (Definition)

Could mean interventional neuro radiology which is minimally invasive field, or international normalized ration which is a lab ...Read more


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Thank you. What is causing the high INR level of 15+. Could it be cancer. It was 17.9 two weeks ago.

Thank you. What is causing the high INR level of 15+. Could it be cancer. It was 17.9 two weeks ago.

Coumadin (warfarin): Assuming your not on Coumadin (warfarin), other causes include liver disease, blood factor deficiencies.

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Can amikacin 500 cause high INR level?

Improbable: This has not been documented as a side-effect of any of the aminoglycosides.

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What's a high INR level?

What's a high INR level?

Anything above 1.5: The inr is a measure of how "thin" the blood is, typically due to the use of prescription blood thinners such as Coumadin (warfarin). A normal inr is 1.0. Anything above that is abnormal. For people on coumadin, the typical goal inr is 2.5 to 4.0 depending on the particular condition it is being used for.

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What are the symptoms of high INR level?

Bleeding: Bleeding while brushing teeth. Easy bruising. Pink urine. Extra heavy periods. Simple cuts taking a long time to stop oozing.

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My INR level keeps varying from as high as 8+ to 1.4 as present. Is there anything I can do to stabilise it?

Several things: A consistent diet avoiding vitamin k rich foods, timing the medication correctly, and avoiding antibiotics (if you can) is a start. There are also some new medications that anticoagulate without having to follow inrs -- talk to your doctor.

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Can voltarin cause high INR levl?

Shouldn't: Voltaren (diclofenac) is a non-steroidal anti-inflammatory agent, and may affect your platelet function. This may increase your bleeding risk on warfarin without increasing your inr.

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Can a hepatic dysfunction cause an elevated INR?

Can a hepatic dysfunction cause an elevated INR?

Yes.: Good liver function is important in the production of blood clotting factors.

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Can a high INR level effect blood pressure?

Can a high INR level effect blood pressure?

No: Only if the inr is so high that there is spontaneous and severe bleeding in which case the BP tends to go down (rapidly).

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If a pt has a high INR (2.1 & 2.2) but is not on Coumadin (warfarin) should a work up be done to determine the cause? Why? What would a work up consist of?

If a pt has a high INR (2.1 & 2.2) but is not on Coumadin (warfarin) should a work up be done to determine the cause? Why? What would a work up consist of?

Absolutely: High INR indicates impaired blood clotting. It can be caused by advanced liver disease, severe infections, certain types of cancer, very large blood loss, and severe malnutrition. It definitely needs to be investigated if the cause is not obvious.

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My INR level has increased constantly from therapeutic level (2-3) to recently 3.7, despite reduced warfarin dosis. What is the caused? Thank you

My INR level has increased constantly from therapeutic level (2-3) to recently 3.7, despite reduced warfarin dosis. What is the caused? Thank you

Warfarin: New medication, diet, different generic rx and then we don't know, I often prescribe brand name Coumadin (warfarin) as there is less variation than generic rx and little room for error.

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My INR level increased, but I haven't changed my diet. It was supposed to remain 2.0-3.0. Today, it was 3.2. My leg began to hurt is this the cause?

Not the cause.: Don't think the pain in your keg caused your inr to go up to 3.2. The inr typically fluctuates when you take warfarin (coumadin). 3.2 isn't bad, with small adjustments it should back to within range.

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What causes your INR level to go from 2.3 to 1.3 and I am in coumadin (warfarin)?

What causes your INR level to go from 2.3 to 1.3 and I am in coumadin (warfarin)?

Multiple factors: Coumadin (warfarin) interacts with a number of gods and medications. Please check the following link for detailed information. Http://m.circ. Ahajournals. Org/content/119/8/e220.full.

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Can a high INR cause symptoms of dementia or alzheimers?

Can a high INR cause symptoms of dementia or alzheimers?

Inr: A high inr in of itself doesn't cause dementia or Alzheimer's disease. Whether it's due to taking anticoagulant like warfarin or because of liver disease, an elevated inr increases the tendency for bleeding, however.

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D-dimer level. 76 High. INR test 1.1 High. Total Protein 8.6 HIGH. Diffuse fatty infiltration liver. What could this mean?

D-dimer level. 76 High. INR test 1.1 High. Total Protein 8.6 HIGH. Diffuse fatty infiltration liver. What could this mean?

Need more info: Diffuse fatty infiltration can have many causes, common ones being fatty liver due to alcohol and fatty liver associated with obesity, metabolic syndrome and diabetes. It would require more information to settle the issue. However, if you are even slightly overweight, reduce you weight through diet and exercise, not easy, but essential.

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Is excessive sleep in an 80 years old a warning sign for a stroke? Given that we have high INR level? And trying to maintain it using coumadin (warfarin).

No.: Stroke does not have warning signs except for transient neurologic symptoms which are only recognized as transient in retrospect. Sleeping is not a warning sign nor is it associated with elevated inr. You should have had a frank discussion with your provider about the risks and benefits of Coumadin (warfarin) therapy using the chadsvasc and possibly hasbled scoring systems.

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Ben having high INR levels 6.2 and chest pain with shortness of breath. Went to ER and they sent me home. Still having CP and short of breath?

Ben having high INR levels 6.2 and chest pain with shortness of breath. Went to ER and they sent me home. Still having CP and short of breath?

No PE @ 6.2: I would b more worried about a bleed of some sort in the thorax, mediastinum or ever cardiac. Call ur pulmonologist and let him know.

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Can high INR cause blood in urine on its own or does it just highlight and underlying problem? I had INR of 5.6 and bloody urine. Went to ER/sent home

Can high INR cause blood in urine on its own or does it just highlight and underlying problem? I had INR of 5.6 and bloody urine. Went to ER/sent home

See below: An INR of 5.6 alone could cause blood in urine. The issue may need to be reexamined once you have your INR in the therapeutic range. Please discuss it with the doctor prescribing the anti-coagulant. Wish you good health.

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Can a high INR (5.8) cause my feet to go numb while sitting? I take Coumadin (warfarin) daily for a clotting disorder.

Can a high INR (5.8) cause my feet to go numb while sitting? I take Coumadin (warfarin) daily for a clotting disorder.

If the high: Inr was going to cause numbness I would expect it to occur whether sitting or standing. Otherwise, I would blame the numbness on a nerve impingement when sitting. Irrespective of the fact you take the coumadin).

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