Doctor insights on:
Causes Of High Cortisol Levels
Brain, cancers: Cortisol production is regulated by the hypothalmus and pituitary gland in the brain. Overproduction of hormones from these brain glands can cause increased production of cortisol. Likewise certain cancers like lung cancer can produce hormones similar to these brain hormones which can cause increased cortisol production. ...Read more
Yes: A spot elevated cortisol means nothing. Appropriate follow-up is a Dexamethasone suppression test, 24 hour urinary cortisol, maybe others if cushingism is a possibility, then a workup for the possible causes, one of which is an adrenal cancer. If you suspect you have cancer, there are better ways of looking for it; I'm glad you had your colonoscopy. Best wishes. ...Read more
Prolactin is elevated naturally in pregnancy and breastfeeding; if neither apply to you and it is markedly elevated, it may be a prolactinoma. See your doctor for further evaluation.
Cortisol elevation can be anything that stresses your body. There are disease states with excessive cortisol production, but these are less likely. Again, discuss with your doctor. ...Read more
Hi cortisol: Yes. Chronically high cortisol is very damaging by causing inflammation throughout the body. It leads to higher incidence of heart attacks, strokes, diabetes, and many more. This is why proper sleep, exercise, other forms of stress reduction such as yoga, tai chi, and meditation are so valuable. ...Read more
What could cause someone with a diagnosed history of 2nd addison's to suddenly havea high acth and high cortisol levels?
Diagnosis?: It's possible that the diagnosis, the dose of cortisone, or the vitamin d therapy has brought about some unexpected results. This needs to be re-evaluated, so stay with it and allow the endocrinologist to sort this out. ...Read more
Cortisol: Blood cortisol varies throughout the day. Although it tends to be higher in the am than the pm, it is pulsatile, and responds to stress. So it is not a simple matter to even define an elevated pm cortisol. Cushing's syndrome elevates both am and pm cortisol and removes the circadian pattern. You don't mention why this was measured. Suggest seeing an endocrinologist. ...Read more
DHEA-s: One common cause in females is PCOS (Polycystic ovarian syndrome). ...Read more
Are there any medications to reverse skin atrophy from cortisone? Also can high cortisol levels in body cause skin thinning?
Maybe and Yes: Yes to the second questions. Localized skin atrophy can be a side effect of cortisone type medications when injected locally. Image guidance, choice of steroid formulation & technique can minimize the risk, but does not eliminate it. It may improve with time. In a few of my own patients, I've had excellent results with dermal fillers injected by plastic surgeon or dermatologist. ...Read more
I'm 36 yo/f my cortisol blood level is 1.32 mcg, normal range says. 07-.93 could this elevation be caused by anxitey/stress? Testosterone is 6.7 high
High cortisol?: 36F from FL sitates her blood cortisol was 1.32 and normal is 0.7 -.93. And asks could this be caused by anxiety stress. ANS Yes but need to know the stress you are taking about. Injury, surgery etc will elevate it but no likely for psychosocial stress to do it. Were you one any pills? What time of day. Best way to assess cortisol is either with a 24 hr urine or testing in saliva. I do 2nd opinion ...Read more
I have a giant liver hemagioma of 17cmx11cmx14cm having this tumor would it cause my cortisol levels to be high and in turn weaken my immune system?
NO: You are born with it, small ones on liver need observation, larger ones some times need surgery for fear of massive hemorrhage and rupture of liver depending on location. Most of the time need segmental recession of involved area (even lobe) Surgery is safe in experienced hands. Speak to your doctor. ...Read more
High cortisol level in evening, high acth level131pg...Mild hypertension., no mass in suprarenal gland, cuahing appearance. Cause?
Possible pituitary: Having a high cortisol with a high acth level is indicative of acth dependent cushings disease. This is a rare disorder due to a pituitary adenoma making too much acth. You may or may not be able to see an abnormality on ct scan or MRI of the pituitary. You should do Dexamethasone suppression testing to confirm the diagnosis. Sometimes the acth is coming from a source outside of the pituitary. ...Read more
Daughter 51 eats & excercises ex. Gained 35 lbs 4 no reason. Blood work shows high cortisol level. Lots stress @ work. Can cortisol cause weight gain?
Yes, but need to:
Find out why is cortisol high?
All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, You also need to be evaluated for glucose intolerance and diabetes. It is imperative to lose weight, not easy, but essential. ...Read more
I have low cortisol, progesterone, estradiol and melatonin levels, and high testosterone. What could cause this combination of abnormalities?
Glandular dysfunctio: Many people have adrenal fatigue which will lower cortisol levels and associated stress will mess up sleep or melatonin. Ovarian dysfunction is also common at earlier age due to poor diets and chemical toxicity even as early as prenatal. Iodine deficiency may be contributing to same. See a dr at acam. Org. ...Read more
What causes low prolactin levels, MRI scans reported at normal? Also low vit d, low cortisol, high folate (folic acid) level. Now have images of MRI and CT myself.
Adrenal gland: YesGet a more detailed answer ›
How high?: It depends on how high it is above normal? If mildly elevated and if you don't have symptoms of cushing's syndrome: fat at mid section, stretch marks in the abdomen, moon-face, buffalo humps...Then this might be just the way you are. If it's very high and you have symptoms of the above, see your doctor to make sure you don't have a pituitary or adrenal tumor overproducing cortisol. ...Read more
Adrenal or Pituitary:
Excessive production of cortisol may result from a tumor in pituitary producing a hormone that stimulates the adrenal gland. Lesions in the adrenal gland, hyperplasia, adenoma, carcinoma, may also cause increase in cortisol levels.
You need to consult your doctor and/or an endocrinologist. ...Read more
Need more info: Hi. If you have Cushing's, which is physical manifestations of cortisol excess and high cortisol, yes, it's treatable. It must be determined if it's ACTH-dependent or ACTH-independent, the tumor localized, and the tumor resected (with a few exceptions in the cases of paraneoplastic Cushing's). After surgery, there are multiple meds that can be used for persistent disease. Good luck! ...Read more
How do: You know you have these hormonal changes? (i am assuming you mean aldosterone) they would be very unlikely to occur together in a human. If they did, you would have a variety of systemic symptoms that would need to be analyzed and treated by your doctor or an endocrinologist. Don't get your medical information from friends, tv or the internet. ...Read more