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Causes Of High Ca 125
Hi, I'm 48 yo, have endometriosis, ovarian cysts, uterine fibroids, pre-menopausal. CA 125 was around 200's then 159 the last one was 210 any concerns?
Likely, no: CA 125 is not recommended as a screening tool for ovarian cancer when used in risk-based stratification. Meaning, assuming that your mom or sister didn't get diagnosed with ovarian cancer. Normal for women with endometriosis to have elevated CA-125. It sounds like your doctor has done Ultrasound to evaluate ovaries as well. Your MD knows your history and risk, likely this CA-125 level is normal ...Read moreSee 1 more doctor answer
Ca125 is also known as Cancer antigen 125. Ca-125 (cancer antigen 125 or carbohydrate antigen 125) is a biomarker/tumor marker for ovarian cancer (etc); however, it is not sensitive or specific enough to use as a screening test. Also, a uk study showed that treating based on ca125 level did not improve outcomes. "125" comes from the 125th attempt to develop a marker. It was introduced by bast ...Read more
Can a hemorhaggic, endometrioma or fibroid cause high level on the ca-125 test? I am 27 y/o with a level of 190. I have a 10cm and 4cm cyst on ovaries
My ca 125 blood test result slightly elevated, with a different reading 3 times, what could cause this to happen?
CA 125: A ca 125 is not a very accurate test. Anything that affects the lining of your abdomen (peritoneum), lung cavity (pleura), or sac around your heart (pericardium) can change the ca 125 level. This includes everything from a cold to kidney failure to cancer. ...Read moreSee 1 more doctor answer
Many causes: It is commonly elevated in ovarian cancer. But it can go up from any reason which causes irritation of the peritoneal lining of your abdomen which includes some benign conditions too. It depends on the level and also if it is going up steadily or staying elevated but stable and not increasing. Your gynecologist can help you to sort it out. ...Read more
Incomplete info: Why did you have the test done? All lab results need to be interpreted in the clinical context and the doctor who ordered the test is usually in the best position to do that. Ca 125 is not a good test to diagnose a primary illness. ...Read more
I have 2 endometromias, 8cm and 6cm on ovarys and also having constipation and burping alot. Ca-125 was normal, can this also cause constipation. ?
Mayne: Ca125 should not be used as a screening test for ovarian cancer. How do you know they are endetriomas? Unfortunately, you don't know what the are until they are out. Any pelvic or abdominal masses can affect the bowels. If this is a new symptom, you should tell your doctor. Btw. Those cysts are a good size..You at higher risk for ovarian torsion which is an emergency. ...Read more
No: there is no clinical evidence that I know of. ...Read more
I had uterine cancer. I had a partial hystroctromy at 24. My blood work came back with high amounts of CA 125. What typically are the next steps?
Work up: Two assumptions. Partial hysterectomy was adequate to Nall endometrial Ca. Also at your age ovary's were left behind. Ca125 is not a diagnostic marker intermittently elevated in ovarian Ca, liver disease and other neoplasms. It can only be used for monitoring known disease. Now work up with CAT scan of abdomen necessary and biopsies to be taken if any lesion seen. ...Read more
2 cysts on left overy. One is simple at 5cm & other is 3.5cm solid. CA-125 normal. Left ovary vol is 99.8, cause weight gain? Could CA-125 be wrong?
Ovarian cysts: Dear Heather-- Simple cysts seen on transvaginal sonography are almost always benign. Solid cysts need to be followed by a gynecologist because of slight risk of ovarian cancer. CA-125 is usually negative with ovarian cysts. Whenever a test result is questioned it should certainly be repeated. One or several ovarian cysts are not related to weight gain. ...Read more
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