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Doctor insights on: Causes Of Essential Thrombocythemia

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What causes essential hypertension in adults?

What causes essential hypertension in adults?

We don't know: "essential" hypertension is a fancy way for us to say that we have absolutely no clue as to why your blood pressure is high. ...Read more

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What is the essential thrombocythemia?

What is the essential thrombocythemia?

ET: It is a condition under myeloproliferative neoplasme umbrella where- for unclear reason- bone marrow produce too much platelet that can go beyond a million. They are sticky and abnormal platelets that can cause blood clots or bleeding. Myeloproliferative neoplasm can transform into acute leukemia. The risk of et to develop acute leukemia is about 5%. Discuss further with your hematologist. ...Read more

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What is a myeloproliferative disorder that includes essential thrombocythemia?

What is a myeloproliferative disorder that includes essential thrombocythemia?

Too many platelets: Myeloproliferative disorders are a set of marrow malignancies characterized by excessive production of certain types of blood cells. Essential thrombocytopenia is one of them, in which marrow makes too many platelets. There are well-tolerated oral agents which help. Other myelodysplastic syndromes are polycythemia vera and chronic myelogenous leukemia. ...Read more

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Is essential thrombocythemia a form of blood cancer? Please advise!

Is essential thrombocythemia a form of blood cancer? Please advise!

By definition: All overgrowths of blood cells and the elements that form them are by definition cancer, since blood cells by their nature travel through the body. Given this, "ET" isn't even a life-shortener on the average, and I hope your illness proves manageable if it needs to be managed at all. ...Read more

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Treatment of essential thrombocythemia with phildephia +ve?

Treatment of essential thrombocythemia with phildephia +ve?

Platelets: Need more information like what is your platelts count and any symptoms. No symptom-no treatment. Since you have diagnosis of essential thrombocythemia and tested positive for philadelphia chromosome mean you have hematologist who has ruled out other causes of thrombocythemia and any lymphocytic leukemia connection. Please stay in touch with hematologist. Wish you best of health. ...Read more

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Causes of aniocytosis?

Causes of aniocytosis?

Anisocytosis, having: Red blood cells (rbc's) of different sizes, can be caused by iron deficiency & sickle cell anemias, folate (folic acid) or vitamin B12 deficiency, autoimmune hemolytic anemia, cytotoxic chemotherapy, chronic liver disease, myelodysplastic syndrome, thalassemia major, & thalassemia intermedia. The unequal-sized rbc's are small in some of these disorders & large in others. ...Read more

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Is there a connection betwen essential thrombocythemia and leukemia?

Is there a connection betwen essential thrombocythemia and leukemia?

Yes-5% risk: Essential thrombocythemia is part of myeloprolifeartive neoplasm umbrealla where in et the bone marrow for some uknown reason-proliferate too much platelet- that can go up above a million. They are abnormal and sticky platelet. Due to the abnormal level and function of platelet, there would be risk for blood clots as well as bleeding. The risk of et to develop into acute leukemia is about 5 %. ...Read more

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Which kind of blood cancer cause idiopathic thrombocytopenia ? Including chronic malignancy

Which kind of blood cancer cause idiopathic thrombocytopenia ? Including chronic  malignancy

By itself: Essential thrombocythemia is a low-grade blood cancer that often requires no treatment. Most unexplained thrombocytosis in people who seem well otherwise is due to iron deficiency. Nobody understands how this works. Hoping you find the answers you need, and glad you asked. ...Read more

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What is the significance of essential hypertension?

What is the significance of essential hypertension?

Long Term Things: If the blood pressure is less than perhaps 200 (on the top number - systolic) then the worries are almost all long-term issues. Damage to the heart, kidneys, and brain are all to be expected with chronic high blood pressure. Damage to other organs often follows these 3. ...Read more

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Why there is pancytopenia in anemia of b12 and folic acid deficiency??

Why there is pancytopenia in anemia of b12 and folic acid deficiency??

Cell maturation: B12 and folic acid are need for DNA synthesis and maturation of all cells. The cells affected are not only red cells, white cell, and platelets but almost all cells in the body, including brain and spinal cord cells. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, low fat milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. Get HPV vaccine. ...Read more

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What is the significance of essential hypotension?

What is the significance of essential hypotension?

Varies: Essential means that it is not secondary to some known cause such as bleeding, dehydration, or an underactive adrenal gland. So if your blood pressure is lower than average it might be said you have essential hypotension. If you feel well, no problem. In fact those with a low BP live longer. There may be some who just feel weak and dizzy with low bp. Sort of a vague not well understood problem, . ...Read more

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Causes of hypergammaglobulinemia?

Causes of hypergammaglobulinemia?

Mono or Polyclonal: High levels of immunoglobulins (hypergammaglobulinemia) can be monoclonal (specific) - due to malignant proliferation of plasma cells or lymphocytes as in myeloma or waldenstrom's macroglobulinemia. Polyclonal (many types) hypergammaglobulinemia is a benign condition due to infection, inflammation causing non-specific gamma globulin production such as in hepatitis, immune and allergic disorders. ...Read more

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Can essential thrombocytosis be inherited?

Can essential thrombocytosis be inherited?

Yes: Essential thrombocytosis can be inherited (autosomal dominant). When inherited, it is called familial essential thrombocytosis. However, mutations can also occur later in life in a non-inherited pattern. ...Read more

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Are metabolic causes of dementia preventable?

Are metabolic causes of dementia preventable?

Yes.: As a rough estimate about 5% of dementias are treatable/preventable, so screening for things like vitamin deficiencies and untreated hypothyroidism should be done as part of an evaluation of patients with early memory loss. ...Read more

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What causes hematologic cancers of the blood?

What causes hematologic cancers of the blood?

Chemicals: And viruses. The cause is unknown in most cases. Some chemicals, e.g., benzene and some viruses, e.g., ebv are known to be associated with hematologic cancers. Some of these cancers due to chromosomal alterations, which are usually acquired through unknown causes. ...Read more

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What is the essential thrombocythemia?

ET: It is a condition under myeloproliferative neoplasme umbrella where- for unclear reason- bone marrow produce too much platelet that can go beyond a million. They are sticky and abnormal platelets that can cause blood clots or bleeding. Myeloproliferative neoplasm can transform into acute leukemia. The risk of et to develop acute leukemia is about 5%. Discuss further with your hematologist. ...Read more

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What exactly is essential thrombocythemia?

What exactly is essential thrombocythemia?

ET: Et is one of the myeloproliferative neoplasms. It causes overproduction of platelets and a susceptibility to clotting and, occasionally, bleeding problems. Whether one needs treatment depends on the patient's age, previous disease-related complications, and underlying cardiovascular status. Several good support groups can be found on the internet. ...Read more

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How many people have essential thrombocythemia (ET)?

Quite common: For the whole population, maybe 1 person in 2000. It's more common in older folks, less so in youngsters. ...Read more

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I have essential thrombocythemia. Is this a life long disease?

Yes : Treatment of essential thrombocythemia depends on your risk of blood-clotting or bleeding episodes. If you're younger than 60, have had no signs or symptoms, and have no other risk factors for developing blood clots, such as smoking, you may simply need periodic medical checkups. ...Read more

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Is there a connection betwen essential thrombocythemia and leukemia?

Yes-5% risk: Essential thrombocythemia is part of myeloprolifeartive neoplasm umbrealla where in et the bone marrow for some uknown reason-proliferate too much platelet- that can go up above a million. They are abnormal and sticky platelet. Due to the abnormal level and function of platelet, there would be risk for blood clots as well as bleeding. The risk of et to develop into acute leukemia is about 5 %. ...Read more

See 1 more doctor answer
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I have essential thrombocythemia and I am taking anagralide. Is this right?

I have essential thrombocythemia and I am taking anagralide. Is this right?

Drugs: Yes, Hydroxyurea and Anagrelide are widely used to treat essential thrombocythemia. There are pros and cons with those two medications. Follow up and discuss in detail with your doctor. ...Read more

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What are the treatment for essential thrombocythemia?

What are the  treatment for essential thrombocythemia?

ET treatment: A drug called hydroxy-urea will be the treatment to reduce platelet levels. Then on the high risk group, Aspirin will be needed too. Discuss in detail with your hematologist. ...Read more

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Is essential thrombocythemia a form of cancer?

Is essential thrombocythemia a form of cancer?

Neoplasm: Essential thrombocythemia (et) is part of group of myeloproliferative neoplasm (mpn) - is a clonal disorder. Mpns are predisposed to clonal evolution and disease transformation to myelodysplasia and/or acute leukemia. The propensity to transform into acute myeloid leukemia differs among the subgroups- being the highest for cml- greater than 90% if left untreated and et being the least - about 5%. ...Read more

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Treatment of essential thrombocythemia with phildephia +ve?

Platelets: Need more information like what is your platelts count and any symptoms. No symptom-no treatment. Since you have diagnosis of essential thrombocythemia and tested positive for philadelphia chromosome mean you have hematologist who has ruled out other causes of thrombocythemia and any lymphocytic leukemia connection. Please stay in touch with hematologist. Wish you best of health. ...Read more

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Is there any alternate treatment for essential thrombocythemia?

Is there any alternate treatment for essential thrombocythemia?

ET: Hydroxyurea, anagrelide, and alpha-interferon are conventional therapies for essential thrombocythemia. Pipobroman is widely used in europe, but not available in the United States. Low-dose Aspirin is possibly effective in preventing thrombosis (clot formation) in et. Low-dose asa is especially effective in managing the vasomotor symptoms of et. ...Read more

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What does myeloproliferative disorder with essential thrombocythemia mean?

What does  myeloproliferative disorder with essential thrombocythemia mean?

Too many platelets: The myeloproliferative neoplasms (mpns) involve terminal myeloid cell expansion in the peripheral blood, resulting in various combinations of erythrocytosis (rbc's), leukocytosis (wbc's), thrombocytosis (platelets), bone marrow hypercellularity/fibrosis, and splenomegaly (enlarged spleen). Essential thrombocythemia is a diagnosis of exclusion, made when other forms of mpn are ruled out. ...Read more

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What is a myeloproliferative disorder that includes essential thrombocythemia?

Too many platelets: Myeloproliferative disorders are a set of marrow malignancies characterized by excessive production of certain types of blood cells. Essential thrombocytopenia is one of them, in which marrow makes too many platelets. There are well-tolerated oral agents which help. Other myelodysplastic syndromes are polycythemia vera and chronic myelogenous leukemia. ...Read more

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What is the difference between polycythemia vera and Essential thrombocythemia?

What is the difference between polycythemia vera and Essential thrombocythemia?

See below: Polycythemia vera (PV) is characterized by uncontrolled production of red blood cells along with specific JAK2 gene mutation and decreased epo level. Essential thrombocythemia (ET) comes with uncontrolled elevation in platelet count. JAK2 mutation occurs only in 50% of ET. Bone marrow biopsy may be required for the diagnosis of ET. Both are clonal myeloproliferative neoplasms. ...Read more

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Is essential thrombocythemia a form of blood cancer? Please advise!

By definition: All overgrowths of blood cells and the elements that form them are by definition cancer, since blood cells by their nature travel through the body. Given this, "ET" isn't even a life-shortener on the average, and I hope your illness proves manageable if it needs to be managed at all. ...Read more

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Is it true that essential thrombocythemia is a form of blood cancer?

By definition: Since the cells of the blood invade tissue, all tumors / clonal overgrowths are by definition cancers. Essential thrombocythemia can usually be kept at bay easily for decades. ...Read more

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I've got essential thrombocythemia. It is a bone marrow disorder. Can it be cured?

I've got essential thrombocythemia. It is a bone marrow disorder. Can it be cured?

May be: It is a mild form of leukemia and may not cause symptoms. Some patients do develop complications. There is no cure through conventional treatments. In some cases bone marrow transplant may be warranted and can cure the disease. See this site for more info. http://www.mayoclinic.org/diseases-conditions/thrombocythemia/basics/definition/con-20034386 ...Read more