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Doctor insights on: Causes Of Elevated Igg

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Can you tell me the most common cause for elevated igg? I had a celiac panel and this was the only abnormal result.

Can you tell me the most common cause for elevated igg? I had a celiac panel and this was the only abnormal result.

Usually nothing: Unless extremely elevated and found to be monoclonal (identical property in layman's term), it usually does not mean much. Other causes include a chronic bacterial infection. ...Read more

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Ebv cause elevated IgG and olioclonal bands yrs.After infection? And cause slightly elevated rheumatoid factor?

Ebv cause elevated IgG and olioclonal bands yrs.After infection? And cause slightly elevated rheumatoid factor?

Yes: Any chronic type infection can cause a disruption of your immune system, and can make lab test positive that are not often clinically relevant. For example, the rheumatoid factor does not mean that you hae rheumatoid arthritis especially if there is little clinical suspicion (this can be determined by your rheumatologist). ...Read more

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Causes if a polyclonal gammopayhy with elevated kappa and lambda free light chains? Seems to be of the IGG type slightly elevated count.

Causes if a polyclonal gammopayhy with elevated kappa and lambda free light chains? Seems to be of the IGG type slightly elevated count.

Polyclonal IgG: It can be caused by numerous inflammatory, infectious, and malignant causes, for example; TB, Rheumatoid arthritis, cirrhosis of the liver, lymphoma, and MS. A more extensive list, click on Table 3 link inside article below. http://www.aafp.org/afp/2005/0101/p105.html http://www.ncbi.nlm.nih.gov/pmc/articles/PMC356447/ Mild elevation could simply be a mild cold with a rhinovirus. No worries. ...Read more

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My IgG is mod low.My dr said i wasn't making antibodies either.Now it shows gamma in my urine and elevated kappa/lamba ratio of 18.25.Whats the cause?

My IgG is mod low.My dr said i wasn't making antibodies either.Now it shows gamma in my urine and elevated kappa/lamba ratio of 18.25.Whats the cause?

Pls c a hematologist: If u haven't seen a hematologist already, u better arrange to c someone soon, ur doctor would help u in that aspect, if he/she is a hematologist, ask 4 more clarification and a side consult of a clinical immunologist would help too, good luck. ...Read more

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What would b the cause of chronic high T cell counts, cd4, 5, 7, and 8. A T-cell beta gene rearrangement, elevated IGG, elevated LGL's, but normal CBC?

What would b the cause of chronic high T cell counts, cd4, 5, 7, and 8. A T-cell beta gene rearrangement, elevated IGG, elevated LGL's, but normal CBC?

Reason for doing it: What was the reason you got this done. In all patients we don't do T cell count, Immunoglobulin level estimation etc. What were your symptoms. Based on your answerc an give a better explanation. In any patient we do CBC- complete blood count with differential count.Only in people with suspected immunodeficiencies/hematological problems-dyscrasias is the term we use, detailed Tcell,B cell ,Ig done ...Read more

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21 yr-old had 8 months of upper respiratory and urinary symptoms, felt caused by infections, and may have immune system disorder on test results.....?

21 yr-old had 8 months of upper respiratory and urinary symptoms, felt caused by infections, and may have immune system disorder on test results.....?

Immune deficiency: Would like to know how low the IgG is . In this case I would consider a functional immune evaluation by studying his pre and post Pneumococcal 23, and Td immune response if the IgG is only borderline low. If it is very low, then IVIG is likely indicated (I have yet had a patient who can tolerate SCIG). I would also like to find out what the urinary culture results are. If they have not been revealing , then a PCR bacterial analysis would be indicated. The mucosal ulcerations is suggestive of an autoimmune disorder and I would include Reiter's syndrome in my diagnosis. ...Read more

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What illnesses are associated with elevated IgG subtype 1 and subtype 3?

What illnesses are associated with elevated IgG subtype 1 and subtype 3?

Immunoglobulins: Igg sublasses one and three are the workhorses of the immune system. The following article may be helping in understanding immunoglobulins. http://primaryimmune.org/wp-content/uploads/2013/06/chapter-5-gg-subclass-deficiency.pdf. Elevations in igg 1 and 3 are typically associated with bacteria and virus coated with simple proteins. ...Read more

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What causes IgG deficency ?

What causes IgG deficency    ?

Many causes: If your IgM and IgA levels are normal or high, it's likely you have one of the still-not-fully-understood genetic glitches that come under the heading of "common variable immunodeficiency" which is very common. If your IgG is just a wee bit below the published "normal", consider ignoring it, but if one or more classes is way low, you deserve an official diagnosis. ...Read more

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What do extremely elevated IgG antibodies to the VZV mean?

What do extremely elevated IgG antibodies to the VZV mean?

Incomplete info: What is the titer of antibodies? Did you have shingles recently? Were you exposed to any one with shingles or chicken pox? All lab results need to be interpreted in the clinical context and the doctor who ordered the test is usually in the best position to do that. ...Read more