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Doctor insights on: Causes Of Elevated C Reactive Protein

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I realise that these markers aren't specific but wouldn't most advanced cancers cause elevated Sedimentation rate and C-reactive protein?

I realise that these markers aren't specific but wouldn't most advanced cancers cause elevated Sedimentation rate and C-reactive protein?

No: Nice to be able to help once again, Matt. The sed rate and especially the C-reactive protein result from the liver pumping out extra large amounts of a couple of particular proteins that are stimulated by very particular things that are often produced in inflammation and seldom in pure neoplasia. Forget most (not all) of what you've read about "immune response to cancer" as myth. Best wishes.

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Why do I have a chronically elevated C reactive protein? I am afebrile, asymptomatic, eat a healthy anti inflammatory diet, have no dental disease.

Why do I have a chronically elevated C reactive protein? I am afebrile, asymptomatic, eat a healthy anti inflammatory diet, have no dental disease.

Ignore it: I'm a pathologist and focused on the lab. Often, I wish we didn't even check CRP's. It's worthless except as an adjunct to the big picture. There's talk of it being a weak coronary risk factor -- but what are you going to do about it? Just live healthy. Plenty of people are in your situation -- we've just created one more thing to worry unnecessarily about. Manage your health & put it out of mind.

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What does it mean if you are prone to getting kidney stones and have regularly elevated neutrophil counts and elevated c reactive protein?

What does it mean if you are prone to getting kidney stones and have regularly elevated neutrophil counts and elevated c reactive protein?

You might have: A chronic kidney infection, so it is best to have a urologist take a look at your condition. Chronic kidney infections can lead to kidney failure.

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Why and What causes your liver to increase output of C reactive protein?

Why and What causes your liver to increase output of C reactive protein?

Inflammation!: CRP is a surrogate marker for inflammation! High levels increase for heart disease whatever the cause!

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C reactive protein really high 61.7mg/l. normal range should be >.05. what is this caused from. Also high ddimer. I'm so scared.

C reactive protein really high 61.7mg/l. normal range should be >.05. what is this caused from. Also high ddimer. I'm so scared.

See below: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, the information you provided suggests inflammation, not necessarily infection. It is not feasible to provide a more meaningful opinion without examining you and you should consult the doctor who ordered the tests.

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Is C-reactive protein always elevated in auto immune conditions?

Is C-reactive protein always elevated in auto immune conditions?

No: Myasthenia gravis, multiple sclerosis, Isaac's, and a host of others will usually not feature elevation. Normal C-reactive protein really rules out nothing. It's an adjunct for a field in which history and physical are still primary.

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I have RA my C-reactive protein was 378.5 what I want to know is if that can cause mental confusion.

I have RA my C-reactive protein was 378.5 what I want to know is if that can cause mental confusion.

Not directly: CRP is a marker of inflammation. When elevated it indicates that your joints are likely inflamed. That can lead to more joint pain, stiffness, and fatigue. The pain can disturb your sleep and that can lead to cognitive difficulties. The symptoms of RA can also result in frustration and that can lead to depression. Depression like poor sleep is associated with cognitive difficulties.

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Dad's ESR is 39, c reactive protein and rheumatoid factor negative what could be the causes?

Dad's ESR is 39, c reactive protein and rheumatoid factor negative what could be the causes?

Non specific: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, ESR is not specific for any disease or disorder. A value of 39 is that high for a 59 year old male. If he does not have any symptoms, if may not be worthwhile to chase a laboratory value.

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My c reactive protein is constantly elevated (~11.6) but my doctor can't find any reason for it. Sometimes my cortisol tests high, but all organs test?

My c reactive protein is constantly elevated (~11.6) but my doctor can't find any reason for it. Sometimes my cortisol tests high, but all organs test?

Stop worrying: This situation is very common and nobody knows what to do about it. Maintain your health like anybody else does, and you can expect the Amanie chances as everyone else of having a good life.

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Are C-reactive protein (CRP) and ESR levels typically elevated with advanced stage cancer such as stage 4 lymphoma?

Are C-reactive protein (CRP) and ESR levels typically elevated with advanced stage cancer such as stage 4 lymphoma?

No: These tests are neither sensitive nor specific for much. They generate enormous confusion and unnecessary fear. C-RP is made in atherosclerotic plaques and is often up in bad atherosclerosis. It's also made in the liver in response to some interleukins in disease elsewhere, especially some arthritis variants. Sed rate reflects globulins and fibrinogen, not usually up in lymphoma.

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I'm 41 y/o F, stage 4 met Melanoma. On Zelboraf & Mekinist. ESR of 85 & C-Reactive Protein 10. Can meds cause this??

Unrelated: ESR and C-reactive protein are laboratory values that are usually not very helpful in following patients with metastatic melanoma. Generally, scans such as CT or MRI are more helpful. Some patients do have an elevation in a laboratory value called LDH which can be helpful to follow.

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What could cause chronic high white blood count, chronic high c reactive protein and occasional high neutrophils and lymph system values.

What could cause chronic high white blood count, chronic high c reactive protein and occasional high neutrophils and lymph system values.

C reactive protein: An elevated c reactive protein is an indicator of inflammation in your body. It is elevated after surgery, with cancer of the lymph nodes, vasculitis such as lupus, or chronic infections such as chronic infections of the bone. The high white count and high neutrophil count could be due to infection. The abnormal lymphocytes could be due to lymphoma or viral infection. Get checked ASAP.

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What is a the implication is chronically elevated Complement 3 and 4 and elevated IGE? Plaquenil has lowered SED rate and C reactive protein.

What is a the implication is chronically elevated Complement 3 and 4 and elevated IGE? Plaquenil has lowered SED rate and C reactive protein.

Infection?: If you are being treated for lupus, a normal C3 is a good thing. However when it is elevated, infection may be the cause. If the IgE is only mildly elevated, it may be from something else such as allergies. But it is highly elevated, one will need to rule out other medical conditions. We really need more details re. Your symptoms.

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Cause of elevations in proinsulin, c-peptides and proinsulin:c-peptide ratio, c reactive protein & ferritin. Normal A1c & glucose. Previously overwei?

Cause of elevations in proinsulin, c-peptides and proinsulin:c-peptide ratio, c reactive protein & ferritin. Normal A1c & glucose. Previously overwei?

Can't answer: Nobody here can answer without your clinical history, though I wouldn't be surprised if you have hemochromatosis -- truth is, I hope you do, because it's the easiest of all the deadly diseases to manage. It's also worth remembering that serum ferritin is an acute phase reactant and likely to be high during some other illness. You're a person, not a set of labs. Insist on a full explanation.

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Could a c reactive protein level of 28 be caused my hip spacer that was put in after hip implant wso removed due to infection?

Could a c reactive protein level of 28 be caused my hip spacer that was put in after hip implant wso removed due to infection?

Infection: Any foreign material can potentially cause inflammation in your body with resultant elevation of c reactive protein, however, before we blame that on the elevation, given your mention of previous infection, I would still rule this out as the cause of the elevation. If it has not been fully treated, it is imperative to control it until further assumptions are made.

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What is implication homogeneous ANA 1:320, compliment 4 high 44, sed rate and c-reactive protein often elevated and vitamin d low?

What is implication homogeneous ANA 1:320, compliment 4 high 44, sed rate and c-reactive protein often elevated and vitamin d low?

Several causes: The vitamin d is probably a seperate problem and should be treated by a supplement. The other lab you reported can be a sign of an autoimmune disease as well as many other diseases. You should discuss the cause with your doctor.

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