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Doctor insights on: Causes Of Cicatricial Pemphigoid

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Is cicatricial pemphigoid contagious? I was just diagnosed with oral cicatricial pemphigoid, and am concerned about passing it on to my wife and children. Is this how it can spread? .

In : In a word, no. It is an autoimmune disease and is not due to some bacteria, virus or fungus that can be transmitted to other individuals. Cicatricial pemphigoid (CP) refers to a group of rare chronic autoimmune blistering diseases that predominately affects the mucous membranes, including the conjunctiva of the eye, and occasionally the skin. Patients with cutaneous involvement present with tense blisters and erosions, often on the head and the neck or at sites of trauma. Scarring of the mucous membranes is common, hence the designation cicatricial, which can lead to decreased vision, blindness, and hoarseness or airway obstruction. This is an autoimmune diseases where environmental factors combined with genetic susceptibility lead to development of autoantibodies. These autoantibioties attack normal tissues causing a separation of the outer layers of the mucosa. This then fills with fluid causing the blisters which ultimately pop exposing the underlying tissues. This leads to scarring (cicatrix) and is responsible for its destructive activity. Patients with mild localized disease may benefit from topical steroids. For more involved lesions the steroied may be directly injected into the affected tissues. Patients with more extensive disease and progressive scarring require systemic. Ref: medscape. ...Read more

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Prednisone60mg/5days, & Promethazine25mg for Bullous Pemphigoid. Med has caused rash popping up all over, even hands/feet. How to treat? ( see pics).

Prednisone60mg/5days, & Promethazine25mg for Bullous Pemphigoid. Med has caused rash popping up all over, even hands/feet. How to treat? ( see pics).

See a dermatologist: Promethazine (phenergan) is of no use for bullous pemphigoid and will do nothing except sedate you. "Rash popping up all over" is too vague a description for any opinion. BP is very serious. How was the diagnosis established? Have you been exposed to other meds? You need immediate attention not available on line. Be sure the DR understands it is URGENT when you call. ...Read more

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What is cicatricial retinopathy of prematurity like?

What is cicatricial retinopathy of prematurity like?

Decreases vision.: Cicatricial retinopathy causes scar tissue in the retina, which is the neural layer of the eye that is used for vision. Usually such retinal changes impinge on vision. A pediatric ophthalmologist (eye doctor) can help assess the extent of the damage and what visual effects to expect and whether any treatment can be helpful. ...Read more

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Who discovered bullous pemphigoid?

Who discovered bullous pemphigoid?

Bullous pemphigoid: Walter Lever described it in 1965. See: http://www.nature.com/milestones/skinbio3/full/skinbio20082a.html ...Read more

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Hi doctors, was just wondering what is cicatricial retinopathy of prematurity?

Hi doctors, was just wondering what is cicatricial retinopathy of prematurity?

Scarring: Scarring of the eye- retina as avreuslt of being born prematurely..Some children wll have impaired vision as a result and others will recover fully with time. Yo can enhance recovery with chinese medicine. I recommend you find someone in your area and talk with them. ...Read more

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How to treat bullous pemphigoid from bacteria?

How to treat bullous pemphigoid from bacteria?

Bullous pemphigoid: This is an acute or chronic autoimmune skin disease, in which there is formation of blisters, known as bullae, at the space between the skin layers epidermis and dermis. It is classified as a type ii hypersensitivity reaction. It is not caused by bacteria, but there is always the possibility of secondary bacterial infection. ...Read more

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I have SLE, & Bullous Pemphigoid (blisters). What would be good to raise low platelets? (Med &/or foods, vitamins)?

I have SLE, & Bullous Pemphigoid (blisters). What would be good to raise low platelets? (Med &/or foods, vitamins)?

Low Plt: Your medication list doesn't have the common medications that cause low Plts. SLE is a common cause. Therapy for low plts is determining cause and treating the same. Would talk to your Rheumatologist and determine how low are the numbers and not all low numbers needs therapy. A blood specialist can look at your blood smear slide and offer a great input. But remember not all number need therapy. ...Read more

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Ross River Virus Jan2014, subsequent rash & pernicious anaemia. Rash appears to be BULLOUS PEMPHIGOLD. Topical ointment NOVASONE largely ineffectual ?

Ross River Virus Jan2014, subsequent rash & pernicious anaemia. Rash appears to be BULLOUS PEMPHIGOLD. Topical ointment NOVASONE largely ineffectual ?

Ouch!: If you haven't, see a Dermatologist - here's good info: http://www.dermnet.com/videos/bullous-diseases/autoimmune-blistering-diseases-of-the-basement-membrane-zone/bullous-pemphigoid-treatment/ You may need systemic corticosteroids but they have some bad side EFX. I hope it helps! Wish I could say 'No worries'. ...Read more