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Doctor insights on: Causes Of Cholestasis

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Can liver disease cause cholestasis?

Can liver disease cause cholestasis?

Sure, but...: Liver disease comes in many varieties and manifestations: cholestasis (either intrahepatic or extrahepatic) with jaundice; infiltrative (like fatty liver, amyloidosis); fibrotic (trending toward cirrhosis); congestive (blood backs up into the liver); ischemic; shock injury; toxic (either metabolic or drug-related); hepatitis (infectious or otherwise, the liver cells are sick); familial; cancer... ...Read more

Cholestasis (Definition)

This means the flow of bile (chole) is held back (stasis). It can be from the liver cells not moving it (often from medications), or from the biliary tree being plugged by stone, tumor, scar, ...Read more


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What causes cholestasis of pregnancy and what are the symptoms?

What causes cholestasis of pregnancy and what are the symptoms?

Itching & Jaundice: As well as elevated blood levels of bile acids. More common in scandinavia, south america, and multiple gestation pregnancy. An increased sensitivity of some women to the estrogen hormones of pregnancy lead to a reduced ability of their bodies to eliminate bile acids, causing them to accumulate. The condition usually resolves within 2-3 weeks of delivery. ...Read more

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Can cholestasis of pregnancy cause long term inflammation to common bile duct? Can hormones affect liver enzymes and itching during period?

Can cholestasis of pregnancy cause long term inflammation to common bile duct?  Can hormones affect liver enzymes and itching during period?

Possibly: the itching is from the cholestasis as it causes the bike to go up and this causes the itching. The inflammation can persist, but can also resolve. External hormone use has to be processed by liver first, so they can place "pressure" on the liver, as can Tylenol, (acetaminophen) and any other medications typically. ...Read more

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What does cholestasis mean?

What does cholestasis mean?

Bile flow: Usually means disruption (slowing or blockage) of bile flow from the liver. ...Read more

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What exactly is cholestasis?

What exactly is cholestasis?

Bile flow: Usually means disruption (slowing or blockage) of bile flow from the liver. ...Read more

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What is the definition or description of: cholestasis?

What is the definition or description of: cholestasis?

Bile plugged: This means the flow of bile (chole) is held back (stasis). It can be from the liver cells not moving it (often from medications), or from the biliary tree being plugged by stone, tumor, scar, or perhaps something else. ...Read more

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Is cholestasis determined by a basic liver function panel?

Is cholestasis determined by a basic liver function panel?

History/Physical/Lab: Cholestasis is diagnosed by doing a complete medical history, physical examination, and blood tests that evaluate liver function, bile acids, and bilirubin. Additionally, an ultrasound can de done to rule out gall bladder stones causing blockage. 1-2 preg/1000 is affected by cholestasis of pregnancy. It may be related to adverse pregnancy events like preterm labor, or at worse, stillbirth. ...Read more

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My 10 year old son has cholestasis liver. What should be done?

My 10 year old son has cholestasis liver. What should be done?

GI Consult: He should see a pediatric gastroenterologist for a full evaluation of the cause of the cholestasis and for treatment. ...Read more

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What is cholestasis of pregnancy?

What is cholestasis of pregnancy?

See below please: Cholestasis of pregnancy is a condition in which the normal flow of bile in the gallbladder is affected by the high amounts of pregnancy hormones. Cholestasis is more common in the last trimester of pregnancy. 1-2 pregnancies/1000 are affected by cholestasis. In severe cases, but not all, cholestasis may increase the risks for fetal distress, preterm birth, or stillbirth. Blood tests are key. ...Read more

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My wife has been diagnosed with cholestasis. How does this affect pregnancy?

My wife has been diagnosed with cholestasis. How does this affect pregnancy?

In bad way: Upon diagnosis, most providers will prescribe ursodeoxycholic acid. While there is no cure for for it, and no way to guarantee a successful outcome, studies have shown a slightly better fetal and maternal outcome from administration of ursodeoxycholic acid, whereas Cholestyramine appears to only relieve itching. Giving vit k during delivary. Delivery by 37 completed weeks is considered crucial ...Read more