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Doctor insights on: Causes Of Avascular Necrosis

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Can corticosteriod shots in my ankle cause bilateral avascular necrosis in my hips? I had two ankle surgeries in the 1990s. The doctor said i had nerve entrapment, i was shot a couple times a year with corticosteriods. I now have bilateral avascular necr

Can corticosteriod shots in my ankle cause bilateral avascular necrosis in my hips? I had two ankle surgeries in the 1990s. The doctor said i had nerve entrapment, i was  shot a couple times a year with corticosteriods. I now have bilateral avascular necr

No: Unless you received injections into your hip the association with the avascular necrosis of your hips is not possible. Long term oral steroid use has been associated with a higher incidence of avascular necrosis but you did not receive this and thereforeminsee no correlatin. ...Read more

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Dr. Pietro Seni
215 doctors shared insights

Avascular Necrosis (Definition)

Also known as osteonecrosis, avascular necrosis is the death of bone from interruption of blood supply. This can result in tiny bone fractures and eventual destruction of the entire bone. It can be caused by trauma, blockage of circulation with lipids in the blood, certain diseases like sickle cell disease, Gaucher, and occasionally after exposure to corticosteroids. Sometimes, there ...Read more


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Could using steriods from chemo cause avascular necrosis?

Could using steriods from chemo cause avascular necrosis?

Yes: This is a known complication of taking steroids, especially if you had to take prolonged courses during your chemo regimen (for acute lymphoblastic leukemia, for example). Depending on the location and extent, treatment ranges from physical therapy and waiting, to some orthopedic surgery procedures. If you are still on steroids, you and your oncologist will have the risk/benefit ratio of stopping. ...Read more

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Why does steroids cause avascular necrosis?

Why does steroids cause avascular necrosis?

We are not sure: We are not sure but there is a linkage seen whether it may be more related ti the underlying problem for which the steroids are given as treatment in the first place. ...Read more

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Do steriods from chemo cause avascular necrosis?

Do steriods from chemo cause avascular necrosis?

Possibly but others: Although avascular necrosis can be related to corticosteroids it is important to know that there are other causes of avascular necrosis. There is a decrease in blood flow to the area involved. Although corticosteroids can be associated, it depends on dose and time and thus chemo steroids are less likely to be associated. Other causes: alcohol, joint injury and increased pressure ...Read more

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Why is the " corticosteroid administration " can cause " avascular necrosis" ? * i need the mechanism how does the " corticosteroid" work.

Why is the " corticosteroid administration " can cause " avascular necrosis" ?
* i need the mechanism how does the " corticosteroid" work.

Not Known: While it is generally agreed that the key problem in avn is compromised blood flow to the bone, the mechanism by which corticosteroid use contributes to avn is not known. It is important to remember that this is a rare and not a common problem in corticosteroid users. ...Read more

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How does prednisone cause avascular necrosis?

Still unknown: Even though there is this very well-established connection between chronic Prednisone use and avascular necrosis, how this occurs remains unclear. Numerous hypotheses abound. Some argue that increased lipids seen with steroids cause vessels to joints to clog, leading to oxygen starvation & bone death. A more popular view is that vessel (venous) walls undergo thickening, leading to poor blood flow. ...Read more

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Why do steroids cause avascular necrosis of the femur head?

Why do steroids cause avascular necrosis of the femur head?

Unknown: No one really knows for sure. However, it has been shown that steroids cause elevation of lipids. In rabbits, steroids cause collections of lipids called an embolism. The emboli caused avascular necrosis of the femoral heads in the studied rabbits. ...Read more

Dr. Charles Glueck
455 doctors shared insights

Osteonecrosis (Definition)

Osteonecrosis is a condition in which part of a person's bone dies due to lack of blood flow to the area. The hip and shoulder are more likely to be affected, but osteonecrosis can also involve the knee, elbow, wrist, or ankle. Trauma to the bone can cause osteonecrosis, often there ...Read more


Necrosis (Definition)

Necrosis is the the death of cells and tissue. In dentistry, root canals are often needed when the pulp tissue inside a ...Read more