Doctor insights on:
Causes Of Autoimmune Hepatitis
Hepatitis is an inflammatory condition of the liver. Almost all cases are caused by viruses, including most commonly hepatitis a, hepatitis b, and hepatitis c, or by toxins (eg alcohol). The liver swells, it doesn't work properly leading to a failure to detoxify some biochemical substances, and a failure to excrete bilirubin, leading to jaundice. Some cases are fatal, ...Read more
I have autoimmune hepatitis. Recently, a cyst was found on my liver (during a sonogram) Could the cyst be serious or cause complications?
It is : Probably is incidental and will not cause a problem. To be sure discuss with your liver doctor. ...Read more
I have autoimmune hepatitis, AST is 28 and ALT is elevated 66. My CRP is 0.1 and my ESR is 2. Does this mean inflammation is not the cause?
Trending up or down?: Some questions to put your concern ; lab results in context: 1) how long have you had autoimmune hepatitis? 2) what treatment are you taking ; have your medications changed recently? 3) alcohol intake (should be minimal)? 3) supplements or steroid use? 4) are your transaminases trending up or down (a useful question if CRP ; ESR are low)? 4) risks for other kinds of hepatitis (viral, etc.)? ...Read more
Rheum is not sure if I have sle, but ALT is 75 U/L.Can sle cause this? What blood tests can be done to diagnose autoimmune hepatitis? is this fatal?
Anti smooth muscle: SLE and some of its treatments can cause increased ALT. There are many other causes of this lab including infection, liver disease, medications, toxin/drug exposure, fatty liver, etc. you should not get to worried if this is the only abnormal lab. The lab test for autoimmune hepatitis is anti smooth muscle antibody. This is a treatable disease but, yes, it can sometimes be fatal. ...Read more
Jaundice & big liver: Skin rashes & spider angioma (see photo) may also be seen. Generally the diagnosis is made when patients present with fatigue, loss of appetite, and weight loss. Examination reveals jaundice. Blood tests reveal liver injury and an autoimmune basis for the injury. Try this website for a more detailed discussion: http://digestive.Niddk.Nih.Gov/ddiseases/pubs/autoimmunehep/ ...Read more
Change: You may need to change to a different immunosuppressive regimen. If your liver specialist is not very experienced in treating this condition, you could consider getting a second opinion. If nothing works and your liver is failing a transplant could be an option. ...Read moreSee 1 more doctor answer
Untreated? cirrhosis: Autoimmune hepatitis is treatable, and often complications can be prevented. There can be a relatively sudden onset of jaundice and malaise, but it does not always have symptoms at first. Untreated autoimmune hepatitis can lead to chronic liver disease and cirrhosis. Complications of cirrhosis can include edema (swelling), jaundice (yellowing of skin), liver cancer, many others. ...Read moreSee 1 more doctor answer
The immune system developed to tell our own, normal cells (self) from foreign and abnormal cells (non-self). This lets the immune system eliminate viruses, bacteria, fungi and cancer cells from our body without harming normal cells. Sometimes the immune system fails to tell self from non-self and it attacks normal cells, for example in ...Read more
Normally our immune system is our body's army. It attacks harmful trespassers like viruses and bacteria that cause infections. Autoimmune hepatitis is one of the diseases when our army gets confused and attacks the liver causing inflammation. I call it a "friendly fire" disease. Other examples of these include ...Read more
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