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Doctor insights on: Causes Of Addiction Genetic Predisposition

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Is alcoholism and addiction hereditary?

Is alcoholism and addiction hereditary?

Absolutely: Irrefutable evidence from multiple different methods support both a biologic basis and a genetic basis (including but not limited to hereditary factors) in addictions. Eric Nestler, MD, PhD is the world's leader in this arena and has many great review articles. ...Read more

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Dr. Vasu Brown
612 doctors shared insights

Addiction (Definition)

Addiction is a primary, chronic disease of brain reward, motivation, memory, and related circuitry. Dysfunction in these circuits leads to characteristic biological, psychological, social and spiritual manifestations. This is reflected in an individual pathologically pursuing reward and/or relief by substance use and other behaviors. A person affected by addiction will be unable to consistently Abstain from use, will have Impaired Behavioral control, will have Craving or increased "hunger" for drugs or rewarding experiences, will have a Dysfunctional Emotional response, and will show diminished recognition of significant problems with their own ...Read more


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Visual learning disorder, what could cause this? Genetics? Environmental factors?

Visual learning disorder, what could cause this? Genetics? Environmental factors?

Non-verbal learning: Disability is far less common than language-based ld's &is found in about 6% of students. Non-verbal learning disorders are brain-based, not eye-based. They may impact executive functions (reasoning, mental flexibility, problem-solving) as well as visual-perceptual &visual-motor tasks, whether isolated or as a manifestion of hydrocephalus, autistic spectrum disorder 1 &some genetic syndromes. ...Read more

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What type of genetic mutation causes albinism?

What type of genetic mutation causes albinism?

Albinism: There are several. Go to wikipedia and https://www.ncbi.nlm.nih.gov/pubmed/ ...Read more

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Are there genetic causes of down syndrome?

Are there genetic causes of down syndrome?

Yes: Down syndrome is a genetic condition caused by an extra copy of chromosome 21. However, it is usually not inherited in families. ...Read more

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What chromosomes cause the genetic disorder achondroplasia?

What chromosomes cause the genetic disorder achondroplasia?

FGFR3 gene: Achondroplasia is a mutation in the fibroblast growth factor receptor 3, which is an inhibitor that regulates bone growth. In cases of achondroplasia, the fgfr3 gene is too aggressive, negatively impacting bone growth. ...Read more

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Are there genetic causes of eating disorders?

Eating DO: The specific causes are unknown. It is however believed to be combination of biological (such as genetic predisposition) , psychological (such as self-image distortions), &/or environmental factors (such as social isolation, early maltreatment, cultural, peer pressure) . As i tell my patients, "genetics loads the gun, environment pulls the trigger". ...Read more

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Is asperger's syndrome caused by genetic, environmental or epigenetic reasons?

Is asperger's syndrome caused by genetic, environmental or epigenetic reasons?

No one knows: Asperger's syndrome now has been incorporated into autism spectrum disorders, which a great deal of work is being done to answer your question. We believe that genetics plays a major role as well as abnormalities in the neurological function in the brain. Environmental issues seem only to treatment and support of the illness. ...Read more

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Is alcoholism more genetic or environmental?

Is alcoholism more genetic or environmental?

Yes: It varies for each individual. It has both genetic and environmental components. I am not sure it matters. If one has the problem, the treatment is the same regardless of which component is contributing more to the problem. ...Read more

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What kind of genetic mutation causes refsum disease?

What kind of genetic mutation causes refsum disease?

Refsum's disease : The following link is a comprehensive review of Refum's disease by the nih. http://ghr.nlm.nih.gov/condition/refsum-disease ...Read more

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Is the genetic disorder aniridia sex linked?

Is the genetic disorder aniridia sex linked?

Nope: Aniridia, complete or partial absence of the iris, can be an isolated birth defect or part of a bigger condition, like wagr syndrome (http://www.Wagr.Org/). The gene that seems to be at the center of the problem is called pax6 and is on chromosome 11p31. Just as many boys as girls are affected. So no, aniridia is not sex-linked. ...Read more

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Is alcoholism a genetic disorder?

Is alcoholism a genetic disorder?

Very often yes: Alcoholism does have a very strong genetic component, there is much research to indicate that many alcoholics brains are different than non, even before their first drink, however the degree of genetic influence would very between persons. The environment or life circumstances however are also part of the disease's expression. It is usually a combo of nature and nurture. ...Read more

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Is there a genetic predisposition for paranoia?

Is there a genetic predisposition for paranoia?

yes, but depends: Certain types of paranoia can have a genetic predisposition, and some times it can be caused by drugs or medications. Your best bet is to get a thorough evaluation by a psychiatrist and get a better answer that is specific to you. ...Read more

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Is there a reason incest leads to a lot of genetic disorders?

Is there a reason incest leads to a lot of genetic disorders?

Double dose of genes: Genetic disorders are more likely to show up from incest because people who are related have many genes in common. Usually the genes that cause genetic disorders are rare but if the parents share genes the baby is likely to get a double dose of the rare gene so the disorder is more likely to be apparent. For some genes it requires the same gene come from both parents to show up in the child. ...Read more

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Is there a genetic factor of epilepsy?

Is there a genetic factor of epilepsy?

Yes: Some epilepsies are clearly genetic- many of these are a type of generalized epilepsy (seizures start both sides of the brain at the same time). Less commonly, some partial epilepsies may be genetic (seizures from one part of the brain). Even some acquired forms of epilepsy may have a genetic component- such as epilepsy secondary to head trauma (though not in every case). ...Read more

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Could environmental factors increased chance of schizophrenia?

Could environmental factors increased chance of schizophrenia?

Environment : Environmental factors can increase one’s chance of getting almost any type of psychological disorders if there is genetic or other physical predisposition. It is widely believed that for most psychological disorders emerge in this way (e.g., someone being exposed to undue stress--deployed to war zones returning with PTSD, schizophrenia due to genetic predisposition and stress ...Read more

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How often is teenage depression related to genetic factors?

How often is teenage depression related to genetic factors?

Sometimes: Real depression have a genetic component. However, teenagers are at a critical time in brain development where they are more susceptible to feeling all emotions more intensely and less likely to have the area of the brain developed that is responsible for planning and thinking things through. This is why 25% of teenagers experience "storm and strife" which is different than depression. ...Read more

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What types of inherited metabolic disorders?

What types of inherited metabolic disorders?

Many types: Metabolic syndrome is insidious. Many features of disease are initially asymptomatic. High blood pressure in early stages is not perceived. Cholesterol issues are asymptomatic unless present for some time. Women may have symptoms of irregular menses, or increased facial hair, but may think this not too abnormal. If you have increasing weight, most on the gut, get checked out by your pcp. ...Read more

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Could preimplantation genetic diagnosis or genetic engineering get rid of diseases like Marfan syndrome?

Could preimplantation genetic diagnosis or genetic engineering get rid of diseases like Marfan syndrome?

Yes: An embryo could be tested for the marfan mutation and only implanted if it did not contain that mutation. The same is true for a large number of other autosomal dominant or recessive diseases. ...Read more

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Is obedience genetic or hereditary?

Is obedience genetic or hereditary?

Obedience : This is an interesting question. It's confused by statements, like: "Something that is hereditary “can” be transmitted genetically from one generation to another." What might be more important to discuss is whether obedience can be taught, and learned, or if it might be something neither taught nor learned in the family setting. Non-obedient parents may model non-obedience for thier children. ...Read more

Genetic (Definition)

From a medical standpoint, "genetic" refers to the potential heritability of various medical conditions. While some conditions are inevitable (at some point in one's life) as a consequence of simple genetic heritability (eg huntington's disease), a large number of medical conditions (including all behaviorial health disorders) are the expressed final pathway of a ...Read more