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Doctor insights on: Causes Of Acute Tubular Necrosis

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What are the causes of acute tubular necrosis?

What are the causes of acute tubular necrosis?

Ischemia, drugs: Acute tubular necrosis (atn) can happen if the kidney has severely reduced blood supply (ischemia). This could be caused by hypotension (very low blood pressure), volume depletion (as a result of illness or trauma), problems with the blood vessels supplying the kidneys (renal artery blockage), and drugs that affect the flow of blood to the kidneys. Drugs and toxins can also directly cause atn. ...Read more

Necrosis (Definition)

Necrosis is the the death of cells and tissue. In dentistry, root canals are often needed when the pulp tissue inside a ...Read more


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I have decreased urination, could this be caused by acute tubular necrosis?

I have decreased urination, could this be caused by acute tubular necrosis?

Very unlikely: Decreased urination almost always relates to either reduced fluid intake or increased fluid losses such as diarrhea or increased sweating. In the rare instance when low urine output is due to kidney disease, weight gain from the accumulated water retention should be measurable on a daily bases. ...Read more

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Can you explain acute tubular necrosis?

Can you explain acute tubular necrosis?

Ischemia, drugs: Acute tubular necrosis (atn) can happen if the kidney has severely reduced blood supply (ischemia). This could be caused by hypotension (very low blood pressure), volume depletion (as a result of illness or trauma), problems with the blood vessels supplying the kidneys (renal artery blockage), and drugs that affect the flow of blood to the kidneys. Drugs and toxins can also directly cause atn. ...Read more

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What is the difference between acute renal failure and acute tubular necrosis?

What is the difference between acute renal failure and acute tubular necrosis?

Here are some...: Acute renal failure is a general term denoting kidneys not able to good enough to manage water and electrolytes due to acute conditions such as shocks from various reasons, and acute tubular necrosis denotes what can be seen in kidney tissue under microscopic exam if biopsy is done, but not necessary for almost all cases. Clinically, they all tell us kidneys not working enough from acute causes. ...Read more

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How is a tubular necrosis diagnosed?

How is a tubular necrosis diagnosed?

ATN: Acute tubular necrosis is classified as a "renal" (i.e. Not pre-renal or post-renal) cause of acute kidney injury. Diagnosis is made by a fena (fractional excretion of sodium) > 3% and presence of muddy casts (a type of granular cast) in urinalysis and by histopathology. ...Read more

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Can a tubular necrosis be found by performing a kidney and bladder ultrasound?

Can a tubular necrosis be found by performing a kidney and bladder ultrasound?

Not usually: Acute tubular necrosis is classified as a "renal" (i.e. Not pre-renal or post-renal) cause of acute kidney injury. Diagnosis is made by a fena (fractional excretion of sodium) > 3% and presence of muddy casts (a type of granular cast) in urinalysis. This cannot be accurately diagnosed by imaging studies. ...Read more

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What's the treatment for acute tubular necrosis?

Complex: Identify the cause of atn, resolve it, and prevent further blood pressure, hypoxia, or nephrotoxin insults while the kidney heals. ...Read more

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What can cause nerve necrosis?

Many concerns: Necrosis is "death" or destruction of a nerve, and this sometimes is necessitated to alleviate pain, by an alcohol injection. If a nerve is cut or transected, or if a nerve cell body dies (apoptosis), from a variety of inflammatory or degenerative causes, recovery is not possible. So, nerve death can occur both in central and peripheral nervous systems. Timely treatment is always best. ...Read more

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What is necrosis? Just irrevesible cell then dead off and cause inflammation?Does it mean whenever there is a mild injury, our cell die and necrosis?

What is necrosis? Just irrevesible cell then dead off and cause inflammation?Does it mean whenever there is a mild injury, our cell die and necrosis?

Necrosis: Cell death is said to occur by two alternative, opposite modes: apoptosis, a programmed, managed form of cell death, and necrosis, an unordered and accidental form of cellular dying. ...Read more