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Causes Of Acute Promyelocytic Leukemia
Chemotherapy: This type of leukemia, apl is a medical emergency. It is treated with standard chemotherapy for leukemia plus a medication called atra (all-trans retinoic acid). In apl, the white cells stop maturing at the promyelocytic phase so atra allows them to mature and the chemotherapy destroys the leukemia. This is probably one the more curable leukemias. Then atra is taken for 2 years as maintenance. ...Read moreSee 1 more doctor answer
A malignant hematologic neoplasm that originates in the bone marrow and represents a clonal proliferation of hematopoietic elements belonging to any of the myeloid, lymphoid, erythroid, and megakaryocytic lineages. Of note, other hematologic neoplasms like lymphoma or myeloma may demonstrate a leukemic phase without actually originating in the bone marrow ...Read more
Good risk: Acute promyelocytic leukemia (APL) is characterized by the presence of "promyelocytes" in the blood and bone marrow. They have a very distinctive appearance. APL arises from very specific gene mutations that puts the disease in a good risk category. This means that the most patients can be put into remission and cured of the disease, using retinoic acid, arsenic trioxide, and chemotherapy. ...Read more
Is there anything i can do about acute promyelocytic leukemia symptoms of bleeding and can it be stopped once started?
Medical emergency!: This is a medical emergency! immediate professional medical care is necessary. Even though acute promyelocytic leukemia generally has a very good prognosis, the occurrence of bleeding may indicate a serious and potentially fatal complication of this disease, namely disseminated intravascular coagulation (dic) that needs to be treated immediately in a hospital setting. Seek professional help now! ...Read more
Is it possible for brief but direct exposure to toxic pest-control chemicals cause acute myelogenous leukemia?
Unknown: Most leukemias in adults and children do not have a specific etiology. Some leukemias in children can be linked to genetic abnormalities like down's syndrome, neurofibromatosis, bloom syndrome, and others. Ethnicity may play a role in all, hispanic children tend to have higer risk. High birth weight has been associated with higher risk though really this is unclear. Other factors are inconsistent. ...Read more
Rephrase question?: Can you rephrase your question? Are you asking about treatment for aml? Treatment would depend on the type and biology/cytogenetic profiles of the aml. Generally speaking- in majority cases would need to get a combination of chemo as an induction then plus minus stem cell transplantation. A derivative of vitamin a- sometimes is given to certain case of aml. Discuss in detail with your oncologist. ...Read more
Most are due to muta: Mutations are common in all cancers. In Leukemia the very first mutation(Single mutation, causing cancer was discovered in Chronic Myelocytic Leukemia(CML). In most other Leukemias, there are multiple mutations present once we have learned how to search for them by Genomic profiling. ...Read more
?: Can you restate the question?Get a more detailed answer ›
Various : Acute leukemia can lead to symptoms (bleeding, fever, infection, weakness) very quickly and requires treatment soon to avoid serious consequences including death. Chronic leukemias are more indolent may take awhile before causing symptoms often diagnose incidentally on a blood count. Treatment depends on the kind of leukemia: myeloid-treated soon to avoid becoming acute; lymphoid-could be watched. ...Read more
Everything: Acute leukemia is presented with the presence of significant level of a very immature blood cells in the circulation and increase level in the bone marrow. It is a very agressive and life threatening. Without treatment people die within weeks and few months only. Chronic leukemia- is progressing slower than acute leukemia. Chronic leukemia can transform into acute leukemia sometimes. ...Read more
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