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Doctor insights on: Causes Of Acute Promyelocytic Leukemia

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What can be done for acute promyelocytic leukemia?

What can be done for acute promyelocytic leukemia?

Chemotherapy: This type of leukemia, apl is a medical emergency. It is treated with standard chemotherapy for leukemia plus a medication called atra (all-trans retinoic acid). In apl, the white cells stop maturing at the promyelocytic phase so atra allows them to mature and the chemotherapy destroys the leukemia. This is probably one the more curable leukemias. Then atra is taken for 2 years as maintenance. ...Read more

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Dr. Liawaty Ho
1,144 doctors shared insights

Leukemia (Definition)

A malignant hematologic neoplasm that originates in the bone marrow and represents a clonal proliferation of hematopoietic elements belonging to any of the myeloid, lymphoid, erythroid, and megakaryocytic lineages. Of note, other hematologic neoplasms like lymphoma or myeloma may demonstrate a leukemic phase without actually originating in the bone marrow ...Read more


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What is the mortality rate for acute promyelocytic leukemia?

What is the mortality rate for acute promyelocytic leukemia?

Good risk: Acute promyelocytic leukemia (APL) is characterized by the presence of "promyelocytes" in the blood and bone marrow. They have a very distinctive appearance. APL arises from very specific gene mutations that puts the disease in a good risk category. This means that the most patients can be put into remission and cured of the disease, using retinoic acid, arsenic trioxide, and chemotherapy. ...Read more

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Acute promyelocytic leukemia symptoms of bleeding, what to do?

Acute promyelocytic leukemia symptoms of bleeding, what to do?

You need a Leukemia: A leukemia expert is what you need to take care of your apl.. There are some brand new drugs other than chemo...They can avoid any risk due to bleeding. ...Read more

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Is there anything i can do about acute promyelocytic leukemia symptoms of bleeding and can it be stopped once started?

Is there anything i can do about acute promyelocytic leukemia symptoms of bleeding and can it be stopped once started?

Medical emergency!: This is a medical emergency! immediate professional medical care is necessary. Even though acute promyelocytic leukemia generally has a very good prognosis, the occurrence of bleeding may indicate a serious and potentially fatal complication of this disease, namely disseminated intravascular coagulation (dic) that needs to be treated immediately in a hospital setting. Seek professional help now! ...Read more

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Will leukemia cause low hemoglobin levels? How quickly does it progress if acute?

Will leukemia cause low hemoglobin levels? How quickly does it progress if acute?

Unlikely: Unlikely acute leukemia, plz see a hematologist. Anemia has many causes at your age most common being iron deficiency. Acute leukemia without therapy is a fatal disease. ...Read more

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What causes acute myelogenous leukemia?

What causes acute myelogenous leukemia?

DNA mutations: Leukemias occur due to mutations in dna. Many mutations have been linked to aml, however, the cause for most of the mutations remains unclear. Known risks include radiation exposure and certain chemical exposure. ...Read more

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Will chronic mylolid leukemia progress to acute and blast stages will it cause kidney disease?

Will chronic mylolid leukemia progress to acute and blast stages will it cause kidney disease?

Unlikely: In the absence of other disease or treatment emergent complications CML is not associated with kidney injury. ...Read more

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Is the course all downhill for acute m leukemia?

No: It depends on patient' s condition, type of response, Cytogenetics, and if a transplant can be done in poor risk disease or not ...Read more

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What are the tests for acute adult leukemia?

Bone marrow exam: The basic tests include blood review, flow cytometry but the definitive test is a bone marrow biopsy which gives the detailed information about type and prognosis of the acute leukemia. ...Read more

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What are the causes of leukemia in children?

What are the causes of leukemia in children?

Unknown: Most leukemias in adults and children do not have a specific etiology. Some leukemias in children can be linked to genetic abnormalities like down's syndrome, neurofibromatosis, bloom syndrome, and others. Ethnicity may play a role in all, hispanic children tend to have higer risk. High birth weight has been associated with higher risk though really this is unclear. Other factors are inconsistent. ...Read more

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What are the symptoms of acute adult leukemia?

Several: Fatigue, fever, easy bruising, infection are some of the symptoms of acute leukemia. Having any of these symptoms, however, does not mean that someone has leukemia. ...Read more

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For acute myelogeous leukemia in a 24-year-old?

For acute myelogeous leukemia in a 24-year-old?

Rephrase question?: Can you rephrase your question? Are you asking about treatment for aml? Treatment would depend on the type and biology/cytogenetic profiles of the aml. Generally speaking- in majority cases would need to get a combination of chemo as an induction then plus minus stem cell transplantation. A derivative of vitamin a- sometimes is given to certain case of aml. Discuss in detail with your oncologist. ...Read more

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Which forms of leukemia are caused by a mutation?

Most are due to muta: Mutations are common in all cancers. In Leukemia the very first mutation(Single mutation, causing cancer was discovered in Chronic Myelocytic Leukemia(CML). In most other Leukemias, there are multiple mutations present once we have learned how to search for them by Genomic profiling. ...Read more

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What are differences between acute and chronic leukemia?

What are differences between acute and chronic leukemia?

Various : Acute leukemia can lead to symptoms (bleeding, fever, infection, weakness) very quickly and requires treatment soon to avoid serious consequences including death. Chronic leukemias are more indolent may take awhile before causing symptoms often diagnose incidentally on a blood count. Treatment depends on the kind of leukemia: myeloid-treated soon to avoid becoming acute; lymphoid-could be watched. ...Read more

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What is the difference between acute and chronic leukemia?

What is the difference between acute and chronic leukemia?

Everything: Acute leukemia is presented with the presence of significant level of a very immature blood cells in the circulation and increase level in the bone marrow. It is a very agressive and life threatening. Without treatment people die within weeks and few months only. Chronic leukemia- is progressing slower than acute leukemia. Chronic leukemia can transform into acute leukemia sometimes. ...Read more

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What is the difference between acute and chronic leukemia ?

Curability: Acute leukemias typically need treatment right away and can possibly be cured. Chronic leukemias are not usually curable because they are typically slower growing. I tell patients chronic leukemias are treatable not curable. Hope this helps. ...Read more

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I want to know what's the main cause of childhood leukemia?

I want to know what's the main cause of childhood leukemia?

Unknown: Just like most other cancers, the cause of leukemia is unknown. ...Read more