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Doctor insights on: Causes Of Acute Intermittent Porphyria

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What are the differences between porphyria and aip (acute intermittent porphyria)?

Classification: Porphyria is a general term for a host of conditions, and acute intermittent porphyria is a variety of a more common variation in this disease category. ...Read more

Dr. Aletha Tippett
92 doctors shared insights

Porphyria (Definition)

Metabolic disorders caused by abnormalities in the synthesis of heme, the portion of hemoglobin which carries the iron inside red blood cells. Symptoms can range from light sensitivity to liver failure to nerve damage to bouts of terrible pain.Special testing is required to ...Read more


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In regards to acute intermittent porphyria, what causes abdominal pain?

In regards to acute intermittent porphyria, what causes abdominal pain?

Great question: AIP causes an axonal neuropathy which starts in proximal arms but spreads throughout limbs, and likely throughout the body. During the cramping attacks, there is an increase in delta-aminolevulinic acid and porphobiilnogen which likely stimulates abnormal nerve activity within the gut. ...Read more

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Can acute intermittent porphyria cause mental illness or psychosis?

Can acute intermittent porphyria cause mental illness or psychosis?

Short answer- YES: The diagnosis of AIP should always be in the differential diagnosis of a person who becomes psychotic& who fits a certain clinical profile which usually includes vague GI symptoms and abdominal pain unexplained neuropathy, and other characteristic symptoms. Feel free to write me more questions on this topic and I'll be happy to answer: www.healthtap.com/drsaghafi ...Read more

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What causes episodes of pancreatitis?

What causes episodes of pancreatitis?

Several things: Alcoholism and gall stones are the most commonly known causes of pancreatitis. High triglycerides can cause it as well, though most causes are referred to as idiopathic. That is, of unknown origin. ...Read more

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Why does acute intermittent porphyria (aip) sometimes cause abdominal pain?

Why does acute intermittent porphyria (aip) sometimes cause abdominal pain?

AIP attacks: Summarized in the following link: https://www.isitaip.com/patient/common-symptoms-of-aip?gclid=CjwKEAjwse7JBRCJ576SqoD7lCkSJABF-bKuavsrIeqpmL2IbvtWeLN7qn1yRJPDCXD3KZWVAwA98xoC-Jfw_wcB

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What could cause sudden onset of severe allergic/auto-immune symptoms?

Vague question: Your question is very vague and does not identify any symptom, so i cannot give you any advice based on it. ...Read more

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Causes of chronic pyelonephritis and treatment?

Causes of chronic pyelonephritis and treatment?

See remark: Very broad question ? Pyelonephritis is basically infection of the kidney ,due to many causes such as presence of stone,infection in the blood stream,infection of bladder due to abnormality of the ureters allowing germs to travel from bladder to the kidneys (this is most common) It is a SERIOUS matter. You should see a specialist,since long standing infection leads to serious complication . ...Read more

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What are the acute and chronic diseases associated with legionella?

What are the acute and chronic diseases associated with  legionella?

Pneumonia: Legionella is a relatively common cause of community-acquired and hospital acquired pneumonias. Legionnaire's disease is a syndrome of pneumonia caused by legionella species. One acute, febrile, self-limited infection caused by legionella is pontiac fever. I am unaware of any chronic infections involving legionella species. Hope this helps. ...Read more

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What are reasons for sudden onset of extreme heat (direct sunlight) intolerance causing severe sunburn/eczema?

What are reasons for sudden onset of extreme heat (direct sunlight) intolerance causing severe sunburn/eczema?

Multiple factors: You don't mention this but certain medications can make you sun sensitive, you were also exposing your skin without sun block I presume as well. If the conditions were right you could have had greater exposure to UV rays than yo thought causing the burns. Its important to always use a physical sun block ...Read more

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What are the symptoms of acute inflammatory polyneuropathy?

What are the symptoms of acute inflammatory polyneuropathy?

CIDP: This is an immune disorder of the peripheral nervous system, and involves an attack of the myelin coverings of mainly the motor nerves, but can be seen occasionally affecting sensory fibers also. Cidp can be controlled with steroids or ivig, but relapses can occur, and lifelong treatment is often required. Weakness in arms, legs, and face, most common. ...Read more

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Symptoms of acute kidney disease?

Symptoms of acute kidney disease?

Decreased Urination: Acute kidney disease represents an attack against the attack usually from profound dehydration, nephrotoxic agents like antibiotics or from bacterial infections. The symptoms range from decrease in urine output, nausea and loss of appetite. The most critical side effect is rapid increase in potassium that can be very dangerous. ...Read more

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What are the symptoms that differentiate chronic pain from acute pain?

What are the symptoms that differentiate chronic pain from acute pain?

Symptom Separation: The duration of pain is typically what determines whether it is chronic or acute. Chronic pain is typically pain that has persisted beyond several weeks to months, and sometimes years. Acute pain is obviously of shorter duration and typically stems from an injury or procedure. If the acute pain transitions into chronic pain, the chronic pain itself can cause other physiologic changes over time. ...Read more

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Are there acute and chronic forms of creutzfeldt-jakob disease?

Are there acute and chronic forms of creutzfeldt-jakob disease?

No: This is an awful and fortunately extremely rare form of a deadly disease. Cjd is thought to be caused by a protein called a prion. The long and short of it....There is no cure. ...Read more

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What are the common causes of intermittent abdominal bloating/distention?

What are the common causes of intermittent abdominal bloating/distention?

Constipation, etc...: A person who feels bloated (in the tummy) off and on is not normal, especially if the bloating is new. A doctor can evaluate to figure out the cause. Problems can be due to eating things the person cannot digest. Some parasites cause bloating. More serious causes of bloating include a build-up of fluid in the abdomen due to kidney disease, liver problems, heart failure, abdominal cancers, etc... ...Read more

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What are the common symptoms of acute stress disorder?

What are the common symptoms of acute stress disorder?

Acute Stress D/O: Acute stress d/o is an anxiety disorder occurring within 4 weeks of event(s) involving threatened death/serious injury or self or others, and response of fear, helplessness, or horror. Lasts at least 2 days and no longer than 4 weeks after the event. Symptoms may include a subjective sense of numbing, detachment, & amnesia; also recurrent images, thoughts, dreams; increased arousal; avoidance. ...Read more

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What are a few causes of chronic intestinal pseudoobstruction?

What are a few causes of chronic intestinal pseudoobstruction?

Genetic and various: The exact cause is unknown but runs in families it is known as primary. If it occurs in older people with underlying chronic diseases it secondary. Parkinson's disease may cause the problem, also diabetes, multiple sclerosis and some collagen disease. It may present like irritable bowel syndrome and abdominal xrays show. There is no cure and medications may help. Surgery is a last resort. ...Read more

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What causes acute myocarditis?

What causes acute myocarditis?

Myocarditis: Most commonly acute myocarditis is causes by a virus. There are other infectious causes such as bacteria or fungus but these are less common. There are also other causes, but again these are much more rare. ...Read more