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Doctor insights on: Causes For Increase In Bun And Creatinine Levels

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I am 49 year old male in good general . A recent blood test showed bun level at 27 and creatinine level at 1.4. Should i be concerned? What are possible causes?

I am 49  year old male in good general .  A recent blood test showed bun level at 27 and creatinine level at 1.4. Should i be concerned? What are possible causes?

Dehydration?: Sounds like dehydration (if no kidney disease) as we grow younger, we cannot rely on our thirst, and have to drink by the clock... Our osmotic receptors get old before we do. ...Read more

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Dr. Madhu Kandarpa
2,192 doctors shared insights

Creatinine (Definition)

Creatinine is a byproduct of creatine phosphate, which is present in muscles. Creatinine levels increase if the ...Read more


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Would losing 12 pounds on an already petite woman and dramatically decreasing protein cause BUN creatinine level to drop from 15 to 6 in 3 months?

Would losing 12 pounds on an already petite woman and dramatically decreasing protein cause BUN creatinine level to drop from 15 to 6 in 3 months?

Loss of muscle mass: In addition to losing fat, you are losing muscle mass and that is reflected in the drop in creatinine. You may wish to increase your protein intake and exercise. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Drink enough water daily so that your urine is mostly colorless. Practice safe sex. ...Read more

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**BUN/creatinine level is 54.7**??? urea nitrogen is 29, creatinine is 0.53, eGFR is 128, potassium is 4.4. Cause for concern? I literally cannot find anything anywhere about a BUN/creatinine level that high.

**BUN/creatinine level is 54.7**???  urea nitrogen is 29, creatinine is 0.53, eGFR is 128, potassium is 4.4. Cause for concern? I literally cannot find anything anywhere about a BUN/creatinine level that high.

BUN/GFR 54.7: I would not worry. It is a ratio-calculated value . Your BUN is 29 ( normal < 20) but that could be due to either mild dehydration or high protein in body( unless you are actively bleeding) . Your creatinine is 0.53 which is great.The ratio is BUN/Cr 29/0.53 = 54.7 . Your GFR another number we look seriously at is 128 great, potassium is 4.4 normal . Do not worry it is an artifact of the math ...Read more

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Can weight gain from prednisone (20lbs) cause an increase in creatinine and bun? Have had increasing labs past 3 months. Been on pred 6mo. Almost off

Unlikely: Prednisone may cause a negative nitrogen balance due to protein catabolism and, therefore, may cause a rise in bun. It may also cause sodium and fluid retention and potassium loss. However, I am unaware of any effects of corticosteroids on serum creatinine or glomerular filtration rate per se. If you do have sle, it is possible that you may have renal involvement. ...Read more

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Sle pt on cellcept (mycophenolate mofetil). If cellcept (mycophenolate mofetil) can cause increased bun why is it used for lupus nephritis? Also can it increase creatinine?

Because it works: Cellcept (mycophenolate mofetil) is the preferred drug for lupus nephritis because it is very effective and has much less risk than alternative meds. It does not cause significant elevations of BUN or creatinine. ...Read more

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Chf patient under 1L water intake a day, BUN level 63, creatinine 2.0 on lasix 40 mg maintenance dosage. Should water intake be increased a little so the kidneys don't conserve water? Asking because of decreased urination wirh stable GFR. Check Adh?

Chf patient under 1L water intake a day, BUN level 63, creatinine 2.0 on lasix 40 mg maintenance dosage. Should water intake be increased a little so the kidneys don't conserve water? Asking because of decreased urination wirh stable GFR. Check Adh?

CHF/ renal disease: This question is best asked to you cardiologist, as you have CHF and kidney damage so your fluid balance is very delicate. Drinking too much can put you back in CHF. Would recheck your creatinine and your creatinine clearence, EF on echocardiogram as it may have changed. Discuss this with your cardiologist ...Read more

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How can I lower my creatinine and bun levels?

Only if due to : Dehydration. If the elevation is due to dehydration you may lower it by drinking water. However, in almost all instances elevated BUN and especially creatinine. Warrant seeing your doctor asap. ...Read more

Dr. Alok Agrawal
255 doctors shared insights

Blood Urea Nitrogen (Definition)

It's level helps evaluate renal function elevation can mean poor renal ...Read more