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Doctor insights on: Causes Elevated Lipase Levels

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What could cause slightly elevated lipase levels?

What could cause slightly elevated lipase levels?

How elevated?: It would help to know the number. Gall stones and alcohol are the common causes of elevated lipase. ...Read more

Dr. Todd Igel
359 doctors shared insights

Lipase (Definition)

Lipases, such as lipoprotein lipase and endothelial lipase, are enzymes that breakdown circulating triglycerides (tg). Specifically, lipases degrade tg rich lipoproteins including chylomicrons, very low density lipoprotein (vldl) and remnant particles produced by breakdown of chylomicron and vldl particles. Decreased lipase function leads to accumulation of ...Read more


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Could drinking the day of a blood test cause slightly elevated lipase levels? Do not drink heavily and never had acute pancreatitis.

Could drinking the day of a blood test cause slightly elevated lipase levels? Do not drink heavily and never had acute pancreatitis.

I think so: I think that if you've never had this problem before, and you had been drinking that same day before the test, then it's certainly possible the alcohol caused an acutely elevated lipase level. If you drink on a daily basis, though, it's also possible that irbid always a little elevated. Maybe repeat the lipase lab when not drinking to check, ok? ...Read more

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Lipase levels were mildly elevated; what would cause this?

High lipase levels: 33 F from Canada notes lipase levels mildly elevated and asks what could cause this. There are many things that can cause this including pancreatitis, gall bladder stone in pancreatic duct, meds, kidney disease, So you really need to ask the Dr who ordered it to interpret it for you as your team there knows you best. You can also google this. But I recommend uptodate.com 4 best source of med info ...Read more

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If my elevated/fluctuating lipase levels were caused by acinar cell carcinoma, would they likely come back down into normal range occasionally?

If my elevated/fluctuating lipase levels were caused by acinar cell carcinoma, would they likely come back down into normal range occasionally?

ACC: 1-2% of total pancreatic tumors in adults. 50% of the cases have high lipase manifesting with fever, arthralgia, rash even in absence of jaundice. Also AFP ( Alfa-feto protein) a cancer marker. Abdominal pain is constant. Appears on CT as a tumor and the fine needle biopsy confirms it. Only fluctuations in lipase is not diagnosis. Any other causes(medication, alcohol, certain foods) are possible. ...Read more

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Have had slightly elevated lipase levels twice over past 8 months (80 and then 61 - reference range to 60). Drink very rarely. Never had acute pancreatitis. Have recently had a normal ct scan. What would cause these abnormal levels?

Relax : Some folks run a high-ish lipase. If you feel well, relax. In pancreatitis it is maybe 5x the upper limit of the reference range or more. Reference ranges are set arbitrarily so that several percent of folks fall above. ...Read more

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Any indication to do a contrast abdominal CT in a patient with marginally increased lipase levels probably caused by elevated triglycerides?

Any indication to do a contrast abdominal CT in a patient with marginally increased lipase levels probably caused by elevated triglycerides?

Not enough info.: generally, a contrasted CT would not be necessary in this instance, but more information about the symptoms, other lab values, such as amylase and white blood count, and the results of a physical exam could change that recommendation. If your lipase is elevated, follow through with your doctor's advice. Good luck. ...Read more

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My lipase levels are elevated. What can this mean?

Maybe nothing: A mild elevation of serum lipase generally means nothing whatever. Even taking an Ibuprofen tablet may raise the level. The reference range is simply what most folks have. Lipase is assayed primarily to rule out acute pancreatitis, which is not a subtle disease and in which lipase is usually several times above the top of the reference range. ...Read more

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What can cause amylase & lipase levels to slightly elevate? They weren't too high like norm is under 300 it was 332. All rad tests are negative!

More than a little: Elevated. Elevations of amylase and lipase are usually due to pancreatic damage, and some times due to intestinal obstruction, renal failure. X-ray is not the most sensitive diagnostic tool for pancreatic lesions. Do you drink; or have gall stones? It would be prudent to consult a gasto-enterologist for a proper workup for your level of enzyme elevations. ...Read more

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What causes low lipase levels on blood test? Lipase 7 IU/L (range is 15-60) Amylase 38 IU/L (range is 28-100) Would this cause symptoms?

What causes low lipase levels on blood test?
Lipase 7 IU/L (range is 15-60)
Amylase 38 IU/L (range is 28-100)

Would this cause symptoms?

Means nothing: Reference ranges are set so that several percent of healthies fall outside on either end. Unless you're obviously sick with bad maldigestion, I would make nothing of this ...Read more

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Can gallstones cause only lipase levels to elevate (and not amylase)?

Depends: if and where gallstones are obstructing biliary system. If gallstones obstruct pancreatic duct and inflame pancreas, both Lipase and Amylase levels can rise, but Lipase is a more specific and accurate measure of pancreatic damage. ...Read more

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If someone has chronic pancreatitis, will their amylase and lipase levels always be elevated? Or only during flare ups?

Not Necessarily: Serum amylase and lipase may or may not be elevated in cases of chronic pancreatitis, depending on the severity of inflammation and cell damage. Of the two, lipase is more likely to mildly elevated. While lipase is specific to the pancreas (amylase comes from other sources), both are commonly elevated in cases of acute pancreatitis. ...Read more

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Elevated lipase level two days in row. Recent VSG surgery. No pain or other symtpoms. Just lipase. Does this mean cancer?

Elevated lipase level two days in row. Recent VSG surgery. No pain or other symtpoms. Just lipase. Does this mean cancer?

Pancreatitis or VSG: A vertical sleeve gastrectomy removes about 75% of stomach, including the part that covers a lot of the pancreas. Both surgery in this area and general anesthesia can cause elevations in lipase, which represent pancreatitis. CANCER NEVER ELEVATES LIPASE (very rare cases). Lipase must have been measured because of pain -- no other reason. Could also be a leak or an ulcer. Rec endoscopy & CT. ...Read more

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How elevated do lipase levels typically get in someone with acinar cell carcinoma of the pancreas?

How elevated do lipase levels typically get in someone with acinar cell carcinoma of the pancreas?

See below: Ms. Amanda: Unfortunately there are no good tests for screening for pancreatic cancer. Lipase is not reliable and lumpy fat is a quack thing.
You may consult this site for info on this topic:
http://www.cancer.org/cancer/pancreaticcancer/detailedguide/pancreatic-cancer-detection ...Read more

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My serum lipase level was 70, normal lab value is 0-60. All other values within normal range. No symptoms. W/F, 51 yoa. Cause for concern?

My serum lipase level was 70, normal lab value is 0-60.  All other values within normal range.  No symptoms.  W/F, 51 yoa.  Cause for concern?

No: it is within normal variation but the question is why did you have it checked anyway are you concern about pancreas or other organ in human body
when you answer that we might be able to provide even a better answer
good luck
thank you for using health tap ...Read more

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What would cause low Creatinine and Lipase levels in my son's bloodwork? He is 9 and has chronic abdominal pains for over a year.

What would cause low Creatinine and Lipase levels in my son's bloodwork?  He is 9 and has chronic abdominal pains for over a year.

Low creatinine: can come from a lack or low levels of muscle mass. Most young children can have this phenomenon without real disease. Low lipase levels are usually more complicated as it depends on the condition in which blood was taken. Lipase is a digestive enzyme produced by the pancreas. Low levels of lipase can indicate cystic fibrosis, where the pancreas is permanently damaged, or chronic pancreatitis. ...Read more

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When lipase levels do elevate because of pancreatic cancer, how high do the levels tend to get? Very high or just slightly elevated?

When lipase levels do elevate because of pancreatic cancer, how high do the levels tend to get? Very high or just slightly elevated?

May/may not. Unrelia: Lipase is not a reliable test for making a diagnosis of Pancreatic Cancer. It is test which is largely limited in its usfulness, mostly for cases of pancreatitis. ...Read more

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I had abdominal pain. Vomitted for 2 times. Got hospitalized. Elevated lipase level 111. Doc says its pancreatitis, but i had doubt. Maybe its not?

I had abdominal pain. Vomitted for 2 times. Got hospitalized. Elevated lipase level 111. Doc says its pancreatitis, but i had doubt.  Maybe its not?

Pancreatitis: Yes, it could be a pancreatitis. Alcohol consumption , gallbladder stones with obstruction of the pancreatic duct are some of the causes. Amylase and lipase levels will be increased in pancreatitis. Your doctor may order US or CT of your abdomen to diagnose the gallbladder or pancreas diseases. ...Read more

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I bloat & get stomach pains no matter what i eat or drink, even tea & water. My lipase levels were high, 352. What could cause this? Is it all related

Two separate issues: The bloating and gas may very well be unrelated to your elevated lipase (two separate issues). Bloating and gas may be due to celiac disease or ibs related. An elevated lipase level may be pancreatic in origin (pancreatitis) but may also have other non-pancreatic sources. Evaluation by a gastroenterologist would be appropriate. ...Read more

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Why would I have intermittently only slightly elevated lipase levels? Normal abdominal ultrasound and ct scan with contrast?

Why would I have intermittently only slightly elevated lipase levels? Normal abdominal ultrasound and ct scan with contrast?

Many possibilities: Do you drink alcohol? There are other possibilities bayou seem to be under the care if a doctor. Give him a good history and see what your doctor tells you ...Read more

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Ultrasound:Normal sized pancreas with non-parencymal disease. Elevated lipase level 111. Vomiting, abdominal pain. Is it pancreatitis?

Ultrasound:Normal sized pancreas with non-parencymal disease. Elevated lipase level 111. Vomiting, abdominal pain. Is it pancreatitis?

Maybe: The fact that ultrasound didn't see anything does not mean you don't have pancreatitis . Laboratory data is needed to complete the work up for possible pancreatitis. Actually CT is better ...Read more

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Can taking Tums (calcium carbonate) and/or Pantoprazole cause lighter than normal stool? Recently had bloodwork done, liver function, bilirubin, and lipase levels normal.

Can taking Tums (calcium carbonate) and/or Pantoprazole cause lighter than normal stool? Recently had bloodwork done, liver function, bilirubin, and lipase levels normal.

Tums (calcium carbonate): Most likely Tums (calcium carbonate) depending on quantity may cause your stool to change but it's not harmful. You should consider an endoscopy if your symptoms persist on pantoprazole ...Read more

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How do I reduce my lipase level?

Why is it elevated?: An elevated lipase is usually an indication of pancreatitis and that needs to be treated by a physician and is not an issue for self diagnosis or treatment. ...Read more

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My lipase level came back as 20, should I be concerned?

No: Serum lipase level of 20 is normal. Why did you have the test done? All lab results need to be interpreted in the clinical context. ...Read more

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Lipase level of 889. How high is this considered? Concerning?

Pancreatitis: Hi. What did the doc who ordered the test tell you? We order tests for a reason to either try to confirm a suspicion or rule it out. In your case, it's looking for causes of your abdominal pain and bloating. Your lipase is high, and the most common reason would be pancreatitis, which certainly could be the cause of your symptoms. Pancreatitis can make you very sick. Talk with your doc. ...Read more