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Doctor insights on: Causes Cleft Lips Palates

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Which antihypertensive drugs that can cause cleft lip/palate if taken during pregnancy?

Which antihypertensive drugs that can cause cleft lip/palate if taken during pregnancy?

ACEi/ ARBs: Not sure there's a drug that links specifically to cleft lip but it is clear that you should avoid ACE Inhibitors and ARBs during pregnancy due to heart and kidney abnormalities that can occur. ...Read more

Palate (Definition)

The palate is the anatomical description of the roof of the mouth. It separated into two parts: the hard palate (more forward) and the soft palate (which is closer to the throat), it separates the mouth ...Read more


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What causes cleft lips and cleft palates?

Embryo failure: During the embryonic stage there is a failure of closure of suture lines. ...Read more

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What is the cause of unilateral cleft lip, submucus palate, tongue tie and bifid uvula in a female baby with first degree relatives parents?

What is the cause of unilateral cleft lip, submucus palate, tongue tie and bifid uvula in a female baby with first degree relatives parents?

Unknown: All 4 conditions can occur individually or in various combinations. Causes for congenital deformities (birth defects) can include environmental factors (maternal nutritional deficiencies), inherited factors as well as spontaneous mutations. Although incest is not common or considered advisable for humans, I am not aware of a specific correlation with orofacial deformities. ...Read more

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Does a cleft lip or cleft palate cause problems for a child?

Does a cleft lip or cleft palate cause problems for a child?

Feeding, then speech: Cleft lip is usually just an appearance issue, but cleft palate can result in early problems feeding, and later with speech. Other problems with teeth, etc can also arise. ...Read more

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I was born with bilateral cleft lip and palate. What caused it?

Unknown: No one really knows why this happens but it is common. Cleft lip and palate appear in one out of 700 live caucasian births in the United States. The clefts can be surgically repaired. ...Read more

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Is a cleft lip and palate caused by mutation, translation, deletion or duplication?

All the above: The genetics for cleft lip and palate is only partially understood. There are a number of genetic mutations (deletions, duplications among them) that can be associated with clefting. There is no single genetic explanation. ...Read more

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Are cleft lips/palates hereditary?

Yes: Cleft lip and palate is often hereditary, but can also appear for the first time in a family. About 40% of the time the cause of the cleft can be figured out. The rest of the time we don't know the cause. Hereditary clefting can occur frequently or infrequently in offspring. A genetics counselor with a cleft team can help you figure this out. ...Read more

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Can cleft lips and cleft palates be repaired?

Cleft repair: Yes, both cleft lip and cleft palate can be repaired. The website of the cleft palate foundation ( http://www.Cleftline.Org/ ) has useful information about cleft surgery and other aspect of cleft care. ...Read more

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