Doctor insights on:
Cause Of Dermatosclerosis
Bad disease: Scleroderma is a progressive disease that affects the skin and connective tissue (including cartilage, bone, fat, and the tissue that supports the nerves and blood vessels throughout the body). There are two major forms of the disorder. One localize and could effect the whole body. ...Read more
Thickened skin: It is a thickening of the skin usually on the upper back and back of the neck. More common in diabetics and heavier people. Treatment is difficult as medicine is partially effective in preventing progression of problem. ...Read more
Clarify: There is no specific disease called "dermatosclerosis." do you mean scleroderma? If so, treatment options include drugs such as penicillamine, immunosuppressives, and antiinflammatory agents, but there is no definitive cure. If you mean something else, please let us know. ...Read moreSee 1 more doctor answer
I hate: As a surgeon to get involved but i lost my wife in just two years... It is an autoimmune disease of unknown origin. When just suspected a sedimentation rate, ANA levels, anti scl-70 and anti-centromere antibodies should be stat done. A good resource is this web site: http://www.Synnovation.Com/sclerodermafaq.Html i would seek help from a university based rheumatology department... ...Read moreSee 1 more doctor answer
Would scleroderma or another autoimmune disease cause a lumpy/bumpy texture underneath the skin all over? Can only feel, not see.
If you had an autoimmune flare of scleroderma caused by inflammation from tvt bladder sling, would you have all of the sling removed to prevent chronic exacerbation of scleroderma due to tvt material?
Assumption ?!: You are making an assumption that the flare up of scleroderma is due to the sling material. Perhaps the flare up is due to something else such as the anesthesia, or even the surgery itself. Speak to your rheumatologist, and if possible try and review scientific literature (http://www.Ncbi.Nlm.Nih.Gov/pubmed is excellent) before rushing into any additional surgery. ...Read moreSee 1 more doctor answer
Explanation : Yes.Get a more detailed answer ›
Other than crest/scleroderma what other virus/bacteria/disease can cause a positive ANA with centromere pattern?
A lab error: The evaluation of these things by an inexperienced technician / pathologist is fraught with possibilities for error. ...Read more
People aren't understanding my ? I had ANA 1:80 speckled ESR29fat malabsorption unknown cause , POTS syndrome is this a indication scleroderma no skin issues, no Raynaud's phenomenon. all started post pregn
I am 25y old. Can GERD cause complete aperistalsis of esophagus? It's been 3y. Not Scleroderma, Achalasia or any other diseases. My LES=5mmHg. Thanks
GERD alone unlikely: manometric evidence of aperistalsis (not simply on barium test) unlikely from GERD alone, and can be from achalasia or esophageal scleroderma, even without skin findings of latter. You need to see Gastroenterologist or motility expert. Low LES pressure does not rule out achalasia. If you are medical personnel, I refer you to my free GI Motility on line on web via Nature Publishing on this subject ...Read more
23 years old. Have aperistalsis of esophagus-distal, middle, proximal.And gerd(0, 3 mmhg). But not achalasia and not scleroderma. What may be the cause?
Need more info: Any other related symptoms - how did you get this result in first place ? It's rare to have all part of esophagus not moving in young age without underlying problem but could induce by specific drugs as well. Was this measured by functional esophagography? ...Read more
Besides scleroderma what can cause skin that is tightening fingers & neck, hardening hands & patches & lines on arms, legs, & trunk?
Hard skin: Scleroderma literally means "hard skin." it is a connective tissue disease that primarily involves the skin which becomes fibrotic (hardened). Changes also may occur in the blood vessels, muscles, and internal organs. The disease involves autoimmunity whereby the immune system attacks the normal tissues of the body. The cause is unknown. ...Read moreSee 2 more doctor answers
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