Doctor insights on:
Cause Of Calcium Metabolism Disorders
Only in excess: Many studies have shown that a woman who drinks one alcoholic beverage a day or a man who has 2 drinks will live longer than those who drink more or less alcohol. Higher intakes can effect metabolism including calcium especially if there is a poor nutritional intake. ...Read moreSee 1 more doctor answer
Could a long term infection with h pylori impair the metabolism of calcium, as well as the vitamin k?
Not known to but...: I admire your persistence in asking this. I think the reason no one answered yet is no one knows, though i know of no evidence of this ; can think of no mechanism via which this might happen. However, see http://www.Ncbi.Nlm.Nih.Gov/pmc/articles/pmc3166673/ for an interesting possible association. H. Pylori infection is a complex subject- see http://www.Allaboutnutritionalhealing.Com/hpyloristory. ...Read more
See below: No unfortunately not.Get a more detailed answer ›
Yes: Dehydration can result in low blood volume or hypovolemia, which affects tissue perfusion and oxygenetion. The tissues are stressed and produce acids that spill into blood, which cause acidity in the blood. The extent of acidity can be tested and give an idea of the severity of the dehydration. ...Read more
Various conditions: Severe uncontrolled diabetes can cause several metabolic problems. The most dire is diabetic ketoacidosis (dka), which is more common in patients who are Insulin deficient. Dka is a severe form of metabolic acidosis that can lead to multiple organ failure. Very high glucoses can also cause high triglycerides, a disorder of fatty particle metabolism that may lead to pancreatitis and heart disease. ...Read more
Yes, but uncommon: There are metabolic disorders that cause obesity; hypothyroidism, cushing's syndrome. But most of the time it is not so exotic, but some combination of getting older with naturally slower metabolism, eating more (maybe stressed), less exercise, etc, etc. See your doctor to get checked out. ...Read more
Yes. Great Question!: The Amino Acid glutamate plays a central role in nitrogen metabolism & participates in multiple biochemical pathways. Disease examples: autoantibodies to the glutamate receptor kill neurons via activation of the receptor ion channel. Anti-nmda receptor encephalitis is a treatment-responsive inflammatory encephalopathic autoimmune disease associated with anti-nmda receptor antibodies. ...Read more
Can autoantibodies against glutamine synthetase and/or glutamate dehydrogenase cause glutamate metabolism disorders?
Still searching: Glutamine synthase is part of the glutamine synthetase family. Ammonia incorporation in animals occurs through the actions of glutamate dehydrogenase and glutamine synthase. Glutamate plays the central role in mammalian nitrogen flow, serving as both a nitrogen donor and nitrogen acceptor. I am unble to find references in my search so far as to autoantibodies to these but see comment. ...Read more
Could a glutamate metabolism disorder either directly or indirectly cause my stool to constantly have strong ammonia smell for last few years?
More likely GI flora: You are in distress and high gad65 ab can cause brain effects. Environmental influences possible. Avoid tobacco, alcohol, processed foods, dairy, grains except quinoa, and sugar.Eat plenty of fresh vegetables and some wild caught fish. Check 25-oh vit d. Eat 6 equal meals a day followed by relaxation breathing for 5 minutes , and mild exercise for 10-15 minutes. Read kelly mcgonigal. ...Read moreSee 1 more doctor answer
Can high gad-65 autoantibodies cause glutamate metabolism disorder (gmd)? What tests confirm gmd? My plasma ammonia is normal & anti-gad ab's high
Can cause diabetes.: It seems these autoabs can cause stiff man's syndrome, a neurological disorder with impaired motor function and muscle stiffness and spasm. There is also a great deal of glutamic acid decarboxylase in the pancreas and so these antibodies act here and produce diabetes mellitus in the patient. This is likely the metabolic disorder involved. So titers of this ab, glucose, and neural tests help. ...Read more
What could cause disorders of glutamate metabolism besides genetic causes? Viruses? Heavy metals? Pancreas/liver problems?
Primarily genetic: Almost totally genetic. Why do you believe you have a disorder in glutamate metabolism? ...Read more
What causes you to have a borderline high calcium level but very very low Vitamin D Level? Any diseases or disorders associated with this?
Many: What is your PTH and phosphorus levels and the serum albumin level ? Further testing is needed to determine what is driving the high normal calcium. Are you on medications including calcium pills or tums (calcium carbonate)? The labs should be repeated. I am assuming your vitamin d25 is low that is not unexpected where we live. Talk to your MD. ...Read moreSee 3 more doctor answers
What causes you to have a borderline high calcium level but very very low Vitamin D Level for months now? Any diseases or disorders associated with this? PTH is normal, Albumin is normal and Phos norm
What kind(s) of specialist(s) would be able to diagnose & treat glutamate metabolism disorders and nitrogen metabolism disorders?
1-Step Metabolomics: Any physician can order the most broad-spectrum screen for metabolic disorders: "one-step metabolomics". Here is a link to a video demonstration of the technique. http://www.jove.com/video/2014/one-step-metabolomics-carbohydrates-organic-amino-acids-quantified. ...Read moreSee 1 more doctor answer
Hypercalcemia: High calcium can cause a number of problems. These include bone pain, muscle weakness, nausea and vomiting, confusion and fatigue, and frequent thirst and urination. Unchecked, it can lead to kidney stones and failure, irregular heartbeat, osteoporosis, coma, and even death. ...Read moreSee 1 more doctor answer
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