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Cause Low Platelets
Thrombocytopenia: Acute gout, a very inflammatory condition, is usually assoc. with high platelets, also called thrombocytosis. If a patient with Gout is on treatment called allopurinol to reduce uric acid, than a side effect of this medicine is low platelets. But this is rare; would advise a thorough review of all medications and interactions to be sure that there is no unwanted side effects from medications ...Read moreSee 1 more doctor answer
Low platelets: Low platelet counts are usually not representative of any specific genetic condition, but reflect chronic illness, liver disease, or bone marrow dysfunction. There are some autoimmune diseases such as ITP [idiopathic thrombocytopenia] which occur in people with Lupus, Rheumatoid Arthritis, etc, which have a genetic component. I would consult a genetic counselor for more information. ...Read more
Could a bacteria infecting a pilonidal sinus cause low platelets by a mechanism such as molecular mimicry (causing auto-immune response)?
Speculative: I understand you have idiopathic thrombocytopenic purpura and a pilonidal sinus. I trust you're getting the latter managed properly, these can be very unpleasant. I'd be more inclined to relate your ITP to general immune activation as in HIV, HBV and HCV. With your interest, you'll enjoy http://asheducationbook.hematologylibrary.org/content/2012/1/306.full ...Read more
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