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Doctor insights on: Cathflo Activase Clot Buster

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My husband is hospitalized for dvt. Should he ask for inferior vena cava filter even if he doesn't undergo tpa (alteplase) treatment? (unsure when clot formed.)

My husband is hospitalized for dvt. Should he ask for inferior vena cava filter even if he doesn't undergo tpa (alteplase) treatment? (unsure when clot formed.)

No: The indication for ivc filter placement in a patient with an acute DVT is usually related to a contraindication of the patient to be anticoagulated. If your husband can be anticoagulated then ther is no reason for him to have a filter. ...Read more

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Dr. William Singer
3 doctors shared insights

Cathflo Activase (Definition)

Cathflo Activase is a clot buster which is a kind of ...Read more


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What is the age limit for being given tpa (alteplase)?

What is the age limit for being given tpa (alteplase)?

Gradient: The older one gets, the greater the risk of intracerebral hemorrhage. Especially after age 75 risk escalates. Then this turns on risk-benefit estimation. ...Read more

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What is the age limit for being given tpa (alteplase)?

Used to be rigid: Used to be arbitrary age which i believe was 75 and now is individualized. ...Read more

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What is tpa, (alteplase) and why is it important in stroke?

What is tpa, (alteplase) and why is it important in stroke?

TPA (alteplase): Tpa (alteplase) or tissue plasminogen activator is a subtance that is used to break up clots that form in the body. It has been used to stop heart attacks, strokes or clots that form in the arms or legs. It has even been used to dissolve clots in the lungs with some success. ...Read more

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What should be monitored before administering the tpa (alteplase)?

What should be monitored before administering the tpa (alteplase)?

Complicated : You need to check it with your physician since it depends on many parameters , but generally speaking: head ct, blood pressure, age, time onset of stroke, coagulant estate and use of anticoagulation, history of previous stroke, bleeding and recent surgeries.... ...Read more

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Could you tell me what happens if a person who is not actually having a stroke is given tpa (alteplase)?

Increased bleed risk: Tissue plasminogen activator, or tpa, (alteplase) "dissolves" clots, so the main risk from it's administration is an increased risk of bleeding. One way to reduce the risk is to have strict rules on who it is administered to, based on many factors including time since symptoms began. Another is to administer it right where it is needed, near the location of the artery which contains the clot. ...Read more

Dr. Andrew Berry
12 doctors shared insights

Alteplase (Definition)

Alteplase is a clot buster which is a kind of ...Read more


Dr. Barbara Lavi
3 doctors shared insights

Activase (Definition)

Activase is a clot buster which is a kind of ...Read more