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Doctor insights on: Catecholamines Fract 24hr Urine

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What is the definition or description of: 24hr urine catecholamines?

What is the definition or description of: 24hr urine catecholamines?

See below: A 24 hr urine catecholamine test is done to help diagnose and susequently resect a tumor in the adrenal glands called a pheochromocytoma which results in BP elevation to very high levels periodically. It measures the amount of the hormones epinephrine, norepinephrine, metanephrine, and Dopamine in the urine. ...Read more

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Urine (Definition)

Urine is the product of the kidneys, which is produced to eliminate the waste products of metabolism, manage body fluid balance, &maintain acid-base balance. The blood is first filtered by the kidneys, and the composition of the resulting fluid is then altered depending on the body's needs. It is composed of mostly water, and breakdown products from blood cells impart ...Read more


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What is the reason for checking catecholamine levels in the urine?

What is the reason for checking catecholamine levels in the urine?

Pheo: Anyone found to have hypertension that isn't classic, or to have other symptoms of pheochromocytoma (or in a youngster, neuroblastoma) will get one or more catecholamine checks. ...Read more

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What if the results are negative in the 24 hour catecholamine urine test? 

What if the results are negative in the 24 hour catecholamine urine test? 

R/O adrenal tumor: Catecholamines are typically produced by functioing adrenal tumors causing elevated blood pressure and rapid pulse. This can be ruled out with a normal 24 hour test. ...Read more

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24 hour urine catecholamine for a pheo- if a person does not have an episode during the 24 hours would it still show elevated levels. If so how?

24 hour urine catecholamine for a pheo-  if a person does not have an episode during the 24 hours would it still show elevated levels. If so how?

Usually, yes: A pheo usually secretes catecholamines continuously, so it is not usually necessary to time the collection. These catecholamines yield a lot of breakdown products (eg. metanephrines). However, in some circumstances, if there is a very high suspicion for pheo and the initial tests are negative, and the attacks are sporadic, a urine collection timed with the episode is reasonable. ...Read more

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Why do I have to refrain from tobacco for catecholamines  and metanephrine urine test?

Why do I have to refrain from tobacco for catecholamines  and metanephrine urine test?

Nicotine...: Tobacco contains nicotine. Nicotine gives the body its kick because it stimulates the adrenal glands to produce adrenaline. Adrenaline, or epinephrine, is a catecholamine. If you use tobacco, the test may return as a false positive. ...Read more

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Who would need a urine catecholamine fractionation?

Who would   need a urine catecholamine fractionation?

Possible tumor: Urine catecholamines are separated into dopamine, epinephrine, norepinephrine, vma, and dopa, among others. Each of these metabolites are differently expressed by certain tumors, often in the adrenal gland, or sometimes in other sites. This gives a guide to where to test further, or what else may be giving rise to the symptoms (often high blood pressure, heart beat abnormalities, etc). ...Read more

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Why would a doctor order a 24 hour urine for catecholamines test?

Why would a doctor order a 24 hour urine for catecholamines test?

To check high levels: Elevated catecholamines in the urine can be associated with hypertension, kidney problems or some excess secretion of catecholamines from other body tissues and creat hypertension and flushing. ...Read more

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Could panic attacks cause excess levels of catecholamines in urine tests?

Could panic attacks cause excess levels of catecholamines in urine tests?

Temporary, maybe: 24 hour urine tests for catecholamines are checking for epinephrine, norepinephrine, & other compounds that can be produced by catecholamine-secreting tumors called pheochromocytomas. Panic attacks alone might temporarily raise these levels, but not in sustained fashion like one of these tumors can. When present, pheochromocytomas can cause anxiety and panic attacks and raise urine catecholamines. ...Read more