Doctor insights on:
Cardiac Action Potential
Beta blockers: Beta blockers are the drug of choice for cardiac patients for prevention of future coronary events. The drug can lower the peak heart rate during exercise. However, patients can continue to get a good training effect even on the beta blockers. The benefits of the drugs far outweigh the potential risks unless the person has severe asthma that could be potentially made worse by the beta blockers. ...Read moreSee 1 more doctor answer
Depends: Hypokinesis means abnormally low contraction and wall motion of the segment of the heart. The greater the number of left ventriculuar wall segments with hypokinesis, the worse the overall heart function is, and the greater the chance of developing heart failure and premature death. ...Read more
Bridging the waiting period with a Wearable Defibrillator Vest: Is a wearable defibrillator (WCD) is indicated after diagnosis of NICM, but before criteria for an ICD are met? It is a common scenario. Criteria for an ICD in patients with new NICM require waiting to assess the EF response to treatment (1). In one abstract appropriate shocks were delivered in 7% of pts with an initial diagnosis of NICM (2) -- higher than might have been predicted, as an ICD study in similar pts found a rate of SCD of 1% per year (2). The level of evidence (3) for use of the WCD during the waiting period is low (4) but the stakes may be high. We need more data and professional guidelines. (1) Bridging a Temporary High Risk of Sudden Arrhythmic Death. Experience with the WCD. PACE 2010 (2) Experience with WCD in NICM: A National Database Analysis. JACC 2014 (3) Grading the Strength of a Body of Evidence When Comparing Medical Interventions. Agency for Healthcare Research and Quality. (4) EFFECTIVENESS OF WCD. Int J of Technology Assessment in Health Care 2014 ...Read moreSee 9 more doctor answers
Is Xanax (alprazolam) better at treating panic disorder than ativan or klonipin? & is there any possibility it causes any cardiac effects? Cardiac arrest, arrythmia
Xanax (alprazolam): It is more potent during the panic attack due to its rapid onset of action, although with all those meds. There is potential for abuse, dependency & withdrawal. Any of them at doses higher than recommended daily dose, or if taken along with other meds. That adds to their effect, can lead to respiratory depression & cardiac problems. Close monitoring by a qualified physician is strongly advised. ...Read moreSee 1 more doctor answer
Sular (nisoldipine): Is medicine to treat high blood pressure. Can cause headache, stomach upset, fast heart beats, sore throat, nasal congestion, flushing, swelling, dizziness, rash. Under supervision by your doctor, & taken as prescribed, side effects manageable. Only serious ones are rash/swelling/shortness of breath/fainting. If these occur, call your doctor asap. ...Read more
What is the difference in potential renal side, GI and cardiac side effects of meloxicam versus Naprosyn (naproxen)?
Yes: Dose/amount dependent increase in heart rate. Also orthostatic hypotension due to decreases on autonomic nervous responses manifested with dizziness with position changes. Some reports of more potentially dangerous arrhythmias like atrial fibrillation are appearing now. Do not use it. Not necessary to be high. I will get high with overdoses of friendship, joy and love, self fulfillment, hard work. ...Read more
How can antidysrhthmic drugs changes the shape of various phases of the cardiac action potential?
Drugs: Antiarrhythmic drugs alter the flow rate of various chemicals across the membranes of the electrically active cells of the heart. Depending on what is going on in what phase, the rate of change of that phase will be altered and thus change the overall appearance of the action potential. ...Read more
Does propofol given for surgery predispose susceptible individuals to dangerous possible lethal cardiac arrhythmias?
Propofol safety: Propofol is generally a safe medication when used appropriately. If a patient is given too much, given the medication too rapidly, or if the patient is hypovolemic or already has cardiac issues, Propofol can potentially cause hypotension which may lead to cardiac arrhythmias. There is no direct cardiac dysrhythmic effect but arrhythmias can occur if Propofol is not given with care. ...Read moreSee 1 more doctor answer
A few: Dipyrmiadole is a vasodilating med used in stress testing. Common side effects include flushing, shortness of breath, chest pain and drop in blood pressure. The side effects can be reversed with IV aminophylline. Over all risk is generally low but another agent might be better to use in those with COPD and active asthma(should be avoided) as well as those with slow heart rates or heart block. ...Read more
Is there the same risk of post-operative death (e.G., cardiac arrhythmia) from conscious sedation as there is with general anesthesia?
Muscle and liver: The most important side effects involve problems with liver or muscle. Muscle pain, weakness and inflammation may occur. Liver dysfunction could also be caused by lipitor (atorvastatin). The drug could also interact with other medications so discuss all these with your doctor or pharmacist. ...Read moreSee 3 more doctor answers
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