Doctor insights on:
Carcinoma In Situ In Children
Depends: Depends on where this diagnosis was made. Is a non-invasive disease. Ductal carcinoma in situ of the breast is treated with lumpectomy and sometimes hormone therapy & radiation. Lobular carcinoma in situ of breast is treated as a benign pre-cancerous lesion. Cancer in situ of the colon treated as an early cancer with surgery. Gynecologist can answer this for a cervix lesion. ...Read more
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Since no one has: Answered in a week, I think it is because like me, they do not know what cin is. We all know that carcinoma in situ means the cancer is superficial, not invading through a structure, and generally conveying risk of becoming invasive cancer. This is most prevalently used in breast cancer. However, I cannot contrast to cin. I do not know what that is. ...Read more
Unfortunately High: Anal carcinoma in situ is a rare pre-cancerous condition that often will recur. It may be associated with HIV and is usually directly caused by hpv. Sometimes close observation by anal "mapping" every 3-4 months is enough with small operations to remove any new lesions as needed. In other instances, treatment with imiquimod, laser therapy or radiation therapy might be recommended. ...Read more
Good question: And difficult to tell sometimes. The most straightforward way to put it is that a benign neoplasm will never turn into an invasive malignancy within your lifetime. Cis will eventually turn into one. But, because we don't live forever, cis might not turn into a malignancy during one's lifetime anyway. Pathologists can usually, but not always, tell the difference by microscopic cell exam. ...Read more
Also called lobular: Neoplasia...It forecasts that you will develop a breast cancer in either breast. Some used to do "mirror" biopsies. Others contemplate bilateral mastectomy. Lcis is a risk not a cancer, but the lobular invasive cancer can pose detection problems. Discuss this with a breast cancer team. I would watch very carefully. Lobular cancer makes up only 15% of invasive cancer. ...Read more
"in place": Ductal carcinoma in situ (DCIS) of the breast is a breast cancer which has started in the ducts of milk glands (as most breast cancers do) but not yet invaded beyond that into the fat of the breast. Untreated, it has a high likelihood of becoming invasive breast cancer, a potentially fatal disease. Treated DCIS has a high cure rate. Some with DCIS benefit from taking med to prevent 2nd cancer. ...Read more
Not all invasive: Cancers start in situ, and not all in situ cancers ultimately invade...But a lot do. So, there is no timetable of when that you can rely on. It is reasonable to take care of in situ when you find it, rather than trust an unreliable actor to behave itself the way you might like. ...Read more
Yes BUT: We need to consider that this is probably lobular "neoplasia" vs. Cis. That being said we still feel this is marker of increased cancer risk. We shouldn't neglect putting together fam history, other risk factors, limitations & risks in imaging, etc before discounting antihormonal therapy and rarely surgery. Many do choose close follow-up. Natural treatments may be incorporated with sufficient data. ...Read more
INVASIVE or DCIS?: These terms are incongruous: dcis is, by definition, breast cancer that has not "broken out" of the ducts and entered the adjacent supportive tissue of the breast; invasive, or infiltrating ductal cancer, by definition, has. The treatment of these 2 diseases is quite different since there is a risk of systemic disease with the latter. Please clarify, thanks. ...Read more
I was diagnosed with severe displasia/carcinoma in situ (cin3).I am having a lot of pelvic pain is that normal?
Cervical dysplasia: Cin iii does not cause pain. If there is pain, there is another issue. ...Read more
Can you have low grade superficial bladder cancer then in 6 months develope carcinoma in situ if the bladder. Is that a recurrance or a new cancer?
Yes and no: Bladder cancers arises multifocally. By the time that the first cancer appears, the entire epithelium covering the bladder already bears mutations, and new cancers begin popping up in various places. They are part of the same underlying process although they are individual cancers. This is a tricky concept. I'm glad your disease was detected and hope that you'll get a good outcome. ...Read more
Viral insertion: DCIS is the earliest phase of transformation to malignancy developing in the ductal system before invasion into parenchyma has occurred. It is defined on mammo by clustered microcalcification. In general the long terminal repeat of the MMTV viral genome enters the ductal cell to initiate transformation. With time the cells become aggressive and invade basement membrane helped by the EBV virus ...Read more
Genetic mutations: This is mostly a random event. There's a natural instability in the human genome even if you are never exposed to anything that's obviously a mutagen. The other factors that place you at risk for breast cancer (nulliparity, brca1 / brca2 mutations, etc.) are risk factors here, but no woman (and actually no man either) is immune. ...Read more
Biopsy: A biopsy with review by pathology is how it is distinguished. ...Read more
Should be fine: You will need to have a surgery to remove the breast carcinoma in situ. In addition to that -if you have a lumpectomy- you would need to get an a radiation therapy following the surgery to reduce risk for recurrence and tamoxifen would be recommended to take for 5 years. You should have a mammogram yearly basis and self breast examination is recommended. Prognosis is good as it is not invasive. ...Read more
Good morning. I made a Conization in the cervix in 2008, because I had a carcinoma in situ. I wonder if it is safe to use tampons or menstrual cup?
Safe, and get PAP:
You should continue getting PAP smears, as recommended by your doctor. Tampons or cup is safe.
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex. ...Read more
Had cold knife cone biopsy for cervical carcinoma in situ 4 months ago. Clear margins. Now I am having heavy periods. Concerned?
Not about cvx cancer: There shouldn't be any causality between having the cone and the new onset of heavy periods. The heavy periods don't have any assocation with cervical cancer, (cervical cancer, cis, dysplasia - usually causes bleeding after intercourse, and/or some irregular bleeding, but don't cause heavy periods. ...Read more
Diagnosed w/ ducal carcinoma in situ 5/13. Am menopausal. Had lumpectomy and radiation. Now on tamoxifen. Am rn and at conference heard arimidex (anastrozole).
On right path: You had the best treatment, for your early stage disease you had, tamoxifen is well proved (relatively inexpensive) drug, before switching to Anastrozole (armidex) which has similar function, treatments should not be based on one day conference attended by rn, it should be proven evidence based, given by your highly trained expert oncologist ...Read more
I had a mastectomy of my left breast for a carcinoma in situ in 2011. What blood tests should I get to follow up on my health? I had a mastectomy of my left breast for a carcinoma in situ in 2011 and now I am not really getting any follow ups. I heard tha
Though a medical oncologist could best answer this, there are no blood tests currently recommended for follow-up of dcis (carcinoma in situ) of the breast.
Your best follow-up would be clinical breast exams by an experienced practitioner and mammograms of your other breast annually. If any unusual changes are noted on your mastectomy side (nodules, skin changes, etc.), those should be evaluated promptly.
I hope that helps! ...Read more
Depends on where this diagnosis was made. Is a non-invasive disease. Ductal carcinoma in situ of the breast is treated with lumpectomy and sometimes hormone therapy & radiation. Lobular carcinoma in situ of breast is treated as a benign pre-cancerous lesion. Cancer in situ of the colon treated as an early cancer with surgery. Gynecologist can answer this ...Read more
Means localosed in place. Medical terms is for carcinoma "localized and did not spread out" it is really description of precancerous condition with bad name that disturbs many patients. Carcinoma in situ is not a killer. If left untreated will develop into invasive cancer ...Read more