Doctor insights on:
Carbonic Anhydrase Inhibitor Medication
Will latisse have interactions with other medications i take? I'm on an oral carbonic anhydrase inhibitor for glaucoma. Will using latisse have any adverse affect or interaction? Are there other medications or ointments that might be a problem if used tog
Should : Should not have any adverse affect but may result in an even lower eye pressure. You may see if you eye doctor can switch you form the carbonic anydrase inhibitor to Lumigan eye drops which will help the glaucoma and your lashes at the same time (lumigan and Latisse (bimatoprost) are the same medicine). ...Read moreSee 3 more doctor answers
Is it true Thiamine is a carbonic anhydrase inhibitor (seen a couple of studies) and if so, could it be helpful in idiopathic intracranial hypertensio?
Maybe: The science is a bit sketchy, and mostly Internet based, which does cast suspicion on validity, but seems to be some possible mechanisms by thiamine on CO2 metabolism. If pseudo tumor is present, would certainly try Diamox (acetazolamide) or glycerol, but would not hurt to add thiamine (vitamin B-1), but would not use B-1 exclusively, as I am not convinced of its efficacy. ...Read more
I've read studies that high doses of thiamine can be as effective as acetezolomide in terms of Carbonic anhydrase inhibitor. True? I have IIH.
Maybe so: I can confirm that I have also read studies that suggest that thiamine is a significant carbonic anhydrase inhibitor. Considering the seriousness of the condition that you are treating, you should probably stick with the known effect of diamox (acetazolamide). However, you could discuss this with your treating physician. ...Read more
Helpful drug: Carbonic anhydrase inhibitors (cai) are used mainly to treat two conditions: glaucoma and altitude sickness. They are useful in both conditions and actually mandatory for high altitude climbing. There are side effects from chronic use, mainly kidney stones. Discuss this will your doctor if you think you need them. ...Read more
Yes: Carbonic anhydrase (CA) is an enzyme which converts carbon dioxide (CO2) to bicarbonate (sodium bicarbonate) and a proton (hydrogen ion.) Resveratrol, catechin, silymarin, and curcumin are natural products known as polyphenols. Resveratrol comes from red wine. Catechin is found in tea. Silymarin is an extract of milk thistle. ...Read more
Has anyone with paramyotonia congenita and hyperkalemic periodic paralysis used carbonic anhydrase inhibitors?
Channelopathies: Your question is interesting. Here is a reference that answers it: channelopathies. Moxley iii rt. Curr treat options neurol. 2000 jan;2(1):31-47. Pmid: 11096735 [pubmed - as supplied by publisher] in short, yes. Longer answer, in some situations it can help, in others, it can make matters worse. The reasons are not understood. Go to pubmed and search for that article, then read the abstract. ...Read more
I have paramyotonia congenita and hyperkalemic periodic paralysis and want to try carbonic anhydrase inhibitors?
Are there natural sources of Carbonic Anhydrase Inhibitors? I've read pomegranate, milk thistle and turmeric are? True?
Verify your sources: Sadly, despite a huge level of interest in the medicinal properties of foods, or maybe because of it, there is an enormous amount of false, half true, or exaggerated information on the internet. In regards to CAI in Pomegranate, I found a review article in an Iranian pharmacy journal that cited 2 chemistry review articles, neither of which makes any mention of Pomegranate whatsoever. ...Read more
I have Pseudotumor Cerebri. I've read Pomegranate, milk thistle, turmeric, capsaicin all hold Carbonic Anhydrase Inhibitors naturally. Is this true?
Use with care: I can confirm that pomegranate and turmeric contain some carbonic anhydrase inhibitor activity. However, these do not have enough of this to be clinically useful. It is much more straightforward to take a small dose of diamox (acetazolamide) instead. Although it does not work for everyone with PTC, it helps many. The side effects would be the same if the medicine dose was the same. ...Read more
Yes: When it first came out. My patients did and they did not want it anymore. ...Read more
What over-the-counter medications should I definitely avoid since they counteract my prescribed verapamil and an ACE inhibitor?
Decongestants: Since they could increase BP but this is a relative contraindication. ...Read more
Food is coming back up my throat. Is this gerd? What medication would be advised. Ppi's or h2 inhibitors?
How long do hypertension medications (diuretics vs ACE inhibitors vs Ca channel blockers vs etc.) take to achieve full effect?
Hours to weeks: The oral medications for treating high blood pressure start to work as soon as they are absorbed and the full effect of a single dose occurs within hours. Most blood pressure drugs sustain the reduction in BP for 24 hours so they can be taken once daily. When starting medication or changing dose there may be some further blood pressure reduction over the next several weeks. ...Read moreSee 1 more doctor answer
My father has been given VogsiteMD 0.3mg before bfast as his PP is high,fasting is ok. This medication is an alpha-glucosidase inhibitor. Will it help?
Are mild auditory hallucinations linked to withdrawal from mood disorder medications, serotonin reuptake inhibitors in particular?
Generally, is it true that ACE inhibitors as a class of medication have a fairly weak effect in reducing blood pressure in hypertension?
Clonidine as an anti-hypertensive---is it an ACE inhibitor, arb, beta blocker? What class of medication is it in for hbp?
If a natural weightlifter took anti cancer medication (aromatase inhibitor), shouldn't his testosterone level increase dramatically?
Increase somewhat: Aromatase inhibitors inhibit the effect of estrogen on the pituitary gland as well as elsewhere. As a result they can increase pituitary hormones that stimulate testosterone production modestly, not usually dramatically. By the way, these medications are banned by most major sports ...Read more
Generally, how potent is clonidine when compared to other hypertensive medications, such as beta blockers and ACE inhibitors? Or, is it so individual?
Hypertension: Current 1st line medication for hypertension or high blood pressure is a thiazide diuretic (water pill) like hctz (hydrochlorothiazide) unless you have a compelling reason eg diabetes, heart disease, kidney disease, etc for something else. Clonidine is far down list. It works but all BP meds work. Down side of Clonidine is rebound hypertension if you forget to take dose. Some find it sedating. Potency depends upon dose. ...Read more
In 2011 i was in a study(gs-us-248-0120 ) for hep c. Drugs were tegobuvir, gs5885, gs9451 & ribo. I failed week 2. Am i now resistant to inhibitors?
Yes: The HIV mutates frequently, and when a mutation produces resistance to protease inhibitors this will allow that form of the virus to multiply over other forms which are sensitive. That is one of the reasons for a drug combination which makes single mutational changes less likely to be favorable to the virus. ...Read more
Need more clarity: Please be more specific...which drug and what inhibitor are you asking about???? tell us what exactly is in your mind.Right now it is not clear to me! ...Read more
Can you tell me about drugs called renin inhibitors are used to treat hypertension. explain how they would have this effect.?
See below: Here's everything you always wanted to know but were afraid to ask: http://www.us.elsevierhealth.com/media/us/samplechapters/9780723431855/9780723431855.pdf ...Read more
Have any undesirable effects been seen in long term use of the blood pressure drugs of the ACE inhibitor class?
Same as short-term: Analyses have not shown any clear risks, including with regards to risk of cancer. Risks over long-term appear to mimic that seen in short-term use (e.g. Risk of hi potassium, kidney function abnormalities); sometimes this can show up after years on the medicine. There may even be benefits to chronic use (apart from intended benefits), such as lower risk of diabetes or atrial fibrillation. ...Read moreSee 1 more doctor answer
I take Thaden & Zopiclone. Cytochrome P450 inducers & inhibitors are a huge problem and my diet is limited. What can I do to improve drug metabolism?
What medical information/product training are oncologists and gynecologists given before they prescribe a drug such as an aromatose inhibitor?
Sensitive to arbs and allergic to ACE inhibitors, what drug should I take to control my blood pressure?
What are the best anti-hypertensive drugs to be given for a patient with hyperlipidemia (beta-blocker vs ACE inhibitor)?
Depends on co-morbid: Depends on other co-morbidities. That is, if hypertensive patient is also diabetic, then ACE inhibitor. If patient is hypertensive and has a history of coronary disease, then ACE inhib and beta-blocker given their secondary benefits, etc. Each patient is unique and the whole pic needs to be considered. ...Read more
Is there an effective drug of choice for hypertension that is labile and stress related? ACE inhibitors and ARBs don't stop the spikes.
Labile Bp: The life style approaches would be. 1. Try classic transcendental meditation. Works great for some. Get loseit and track salt sodium intake for a week or fitness pal and do both Na and K. If Na>1,500 mg/ d or K <4,700 mg /d get DASH EATIMG PLAN. POCKET BOOKS, DASH DIET VGOR HTN. Do chap9 exactly for 2 weeks. Get back with me then. ...Read moreSee 1 more doctor answer
Is it right to say that there are currently three different effective drugs for depression: tricyclic, oxidace monoamine inhibitors, and prozac (fluoxetine)?
Antidepressants: There are multiple types of antidepressants. Tricyclics like imipramine, amitriptylene, desipramine; irreversible maoi's like nardil; mao-b inhibitors -- emsam; ssri's like prozac, celexa, ; lexapro; snri's like effexor, pristiq, (desvenlafaxine) and cymbalta; sari's -- tradozone; nassa -- remeron; ndri -- wellbutrin. So the list is longer than you might have thought, and some classes contain more than i named. ...Read moreSee 3 more doctor answers
Why are ACE inhibitors usually not the first line of drug therapy in newly diagnosed cases of hypertension among elderly (55+years)?
How can the therapeutic effects of antacid drugs, h2 blockers, proton pump inhibitor drugs, misoprostol?
Question?: I'm not sure I fully understand what your question is? The drugs you listed all help with symptoms of GERD or stomach ulcers, and they have different means by which they help patients with these problems. The safest and easiest to take are antacids and H2 blockers. Please consider rephrasing your question more specifically. ...Read more
Alpha-1 antitrypsin deficiency. Can this relate to high GGT in liver, breathing heart and lung issues, can it affect medications like ACE inhibitors
ACE: Is produced in the kidneys and lungs. A-1at deficiency affect the lungs and the liver to cause emphysema and cirrhosis. Due to lung problem, the heart can suffer and symptoms could include tachycardia and heart failure due to the emphysema. It also causes chronic cough. From this you can surmise that yes, GGT can be elevated and ace can decrease but kidney can produce enough. ...Read more
Can a ACE test be used to check kidney function on ACE inhibitors?As drugs like ibuprofen and potassium build ups affect blood through kidneys?
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