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Doctor insights on: Carbonic Anhydrase Inhibitor Medication

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Will latisse have interactions with other medications I take? I'm on an oral carbonic anhydrase inhibitor for glaucoma. Will using latisse have any adverse affect or interaction? Are there other medications or ointments that might be a problem if used tog

Will latisse have interactions with other medications I take? I'm on an oral carbonic anhydrase inhibitor for glaucoma. Will using latisse have any adverse affect or interaction? Are there other medications or ointments that might be a problem if used tog

Should: Should not have any adverse affect but may result in an even lower eye pressure. You may see if you eye doctor can switch you form the carbonic anydrase inhibitor to Lumigan eye drops which will help the glaucoma and your lashes at the same time (lumigan and Latisse (bimatoprost) are the same medicine). ...Read more

Dr. Ira Friedlander
6 Doctors shared insights

Carbonic Anhydrase Inhibitor (Definition)

Carbonic anhydrase inhibitors are a kind of water pill or diuretic (heart ...Read more


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Is it true Thiamine is a carbonic anhydrase inhibitor (seen a couple of studies) and if so, could it be helpful in idiopathic intracranial hypertensio?

Is it true Thiamine is a carbonic anhydrase inhibitor (seen a couple of studies) and if so, could it be helpful in idiopathic intracranial hypertensio?

Maybe: The science is a bit sketchy, and mostly Internet based, which does cast suspicion on validity, but seems to be some possible mechanisms by thiamine on CO2 metabolism. If pseudo tumor is present, would certainly try Diamox (acetazolamide) or glycerol, but would not hurt to add thiamine (vitamin B-1), but would not use B-1 exclusively, as I am not convinced of its efficacy. ...Read more

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I've read studies that high doses of thiamine can be as effective as acetezolomide in terms of Carbonic anhydrase inhibitor. True? I have IIH.

Maybe so: I can confirm that I have also read studies that suggest that thiamine is a significant carbonic anhydrase inhibitor. Considering the seriousness of the condition that you are treating, you should probably stick with the known effect of diamox (acetazolamide). However, you could discuss this with your treating physician. ...Read more

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Has anyone tried carbonic anhydrase inhibitors?

Has anyone tried carbonic anhydrase inhibitors?

Helpful drug: Carbonic anhydrase inhibitors (cai) are used mainly to treat two conditions: glaucoma and altitude sickness. They are useful in both conditions and actually mandatory for high altitude climbing. There are side effects from chronic use, mainly kidney stones. Discuss this will your doctor if you think you need them. ...Read more

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Are there are Foods/minerals/supplements which are natural Carbonic Anhydrase Inhibitors?

Are there are Foods/minerals/supplements which are natural Carbonic Anhydrase Inhibitors?

Yes: Carbonic anhydrase (CA) is an enzyme which converts carbon dioxide (CO2) to bicarbonate (sodium bicarbonate) and a proton (hydrogen ion.)

Resveratrol, catechin, silymarin, and curcumin are natural products known as polyphenols. Resveratrol comes from red wine. Catechin is found in tea. Silymarin is an extract of milk thistle. ...Read more

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Has anyone with paramyotonia congenita and hyperkalemic periodic paralysis used carbonic anhydrase inhibitors?

Has anyone with paramyotonia congenita and hyperkalemic periodic paralysis used carbonic anhydrase inhibitors?

Channelopathies: Your question is interesting. Here is a reference that answers it: channelopathies.
Moxley iii rt.
Curr treat options neurol. 2000 jan;2 (1):31-47.
Pmid: 11096735 [pubmed - as supplied by publisher]
in short, yes. Longer answer, in some situations it can help, in others, it can make matters worse. The reasons are not understood. Go to pubmed and search for that article, then read the abstract. ...Read more

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I have paramyotonia congenita and hyperkalemic periodic paralysis and want to try carbonic anhydrase inhibitors?

Then by all means: Speak to your neurologist. We all have to learn about these condition, frankly, they are heavily tested on our board exams; however, rarely actually seen. I'd consider seeing a neurologist with expertise in neuromuscular disorders. ...Read more

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Are there natural sources of Carbonic Anhydrase Inhibitors? I've read pomegranate, milk thistle and turmeric are? True?

Are there natural sources of Carbonic Anhydrase Inhibitors? I've read pomegranate, milk thistle and turmeric are? True?

Verify your sources: Sadly, despite a huge level of interest in the medicinal properties of foods, or maybe because of it, there is an enormous amount of false, half true, or exaggerated information on the internet. In regards to CAI in Pomegranate, I found a review article in an Iranian pharmacy journal that cited 2 chemistry review articles, neither of which makes any mention of Pomegranate whatsoever. ...Read more

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I have Pseudotumor Cerebri. I've read Pomegranate, milk thistle, turmeric, capsaicin all hold Carbonic Anhydrase Inhibitors naturally. Is this true?

Use with care: I can confirm that pomegranate and turmeric contain some carbonic anhydrase inhibitor activity. However, these do not have enough of this to be clinically useful. It is much more straightforward to take a small dose of diamox (acetazolamide) instead. Although it does not work for everyone with PTC, it helps many. The side effects would be the same if the medicine dose was the same. ...Read more

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I want to know what is the function of carbonic anhydrase in the brain.

I want to know what is the function of carbonic anhydrase in the brain.

Acid-base regulation: Carbonic anhydrase (CA) is found throughout the brain. It is concentrated in the areas producing cerebro-spinal fluid and helps maintain that pressure. But all cells have this important enzyme involved in keeping the acid-base balance of the brain and body. ...Read more

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What medications are classified as ACE inhibitors?

What medications are classified as ACE inhibitors?

They end in -pril: Look at the generic medication name. If it ends in "pril" it's an ace inhibitor. Common ones: lisinopril, enalapril, captopril, ramipril etc. Their cousins, arbs end in "artan" as in losartan, irbasartan, etc... ...Read more

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How are lipase inhibitors (orlistat) used as a fat blocking medication?

How are lipase inhibitors (orlistat) used as a fat blocking medication?

Orlistat stool chang: No every body who takes orlistat has fatty stools, that how it works by blocking the absorption of fats
orlistat blocks the absorprtion of fats and fats are in the stools undigested and there is limited absorption. ...Read more

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Has anyone used lipase inhibitors (orlistat) the fat blocking medication?

Has anyone used lipase inhibitors (orlistat) the fat blocking medication?

Yes: When it first came out. My patients did and they did not want it anymore. ...Read more

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What are some different types of ACE inhibitor medications?

What are some different types of ACE inhibitor medications?

ACE-I: ACE-I or angiotensin converting enzyme-inhibitors, usually end with the suffix "-pril." They include benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, perindopril, quinapril, ramipril, and trandolapril. ...Read more

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Food is coming back up my throat. Is this gerd? What medication would be advised. Ppi's or h2 inhibitors?

Food is coming back up my throat. Is this gerd? What medication would be advised. Ppi's or h2 inhibitors?

See your doctor: This is not normal. You need to see your physician to determine the cause of this problem. ...Read more

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How long do hypertension medications (diuretics vs ACE inhibitors vs Ca channel blockers vs etc.) take to achieve full effect?

How long do hypertension medications (diuretics vs ACE inhibitors vs Ca channel blockers vs etc.) take to achieve full effect?

Hours to weeks: The oral medications for treating high blood pressure start to work as soon as they are absorbed and the full effect of a single dose occurs within hours. Most blood pressure drugs sustain the reduction in BP for 24 hours so they can be taken once daily. When starting medication or changing dose there may be some further blood pressure reduction over the next several weeks. ...Read more

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Are mild auditory hallucinations linked to withdrawal from mood disorder medications, serotonin reuptake inhibitors in particular?

Are mild auditory hallucinations linked to withdrawal from mood disorder medications, serotonin reuptake inhibitors in particular?

No: Auditory hallucinations are not associated with withdrawals from ssri's unless they are ringing in the ears. Instead, they can be associated to the mood disorder itself. ...Read more

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Clonidine as an anti-hypertensive---is it an ACE inhibitor, arb, beta blocker? What class of medication is it in for hbp?

Clonidine as an anti-hypertensive---is it an ACE inhibitor, arb, beta blocker? What class of medication is it in for hbp?

Cental alpha agonist: Clonidine acts on the central Alpha receptors and lowers sympathetic tone which lowers heart rate and blood pressure. Clonidine is not a good long term medication due to numerous side effects and ideally has be used for short duration only. ...Read more

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If a natural weightlifter took anti cancer medication (aromatase inhibitor), shouldn't his testosterone level increase dramatically?

If a natural weightlifter took anti cancer medication (aromatase inhibitor), shouldn't his testosterone level increase dramatically?

Increase somewhat: Aromatase inhibitors inhibit the effect of estrogen on the pituitary gland as well as elsewhere. As a result they can increase pituitary hormones that stimulate testosterone production modestly, not usually dramatically. By the way, these medications are banned by most major sports ...Read more

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Generally, how potent is clonidine when compared to other hypertensive medications, such as beta blockers and ACE inhibitors? Or, is it so individual?

Generally, how potent is clonidine when compared to other hypertensive medications, such as beta blockers and ACE inhibitors? Or, is it so individual?

Hypertension: Current 1st line medication for hypertension or high blood pressure is a thiazide diuretic (water pill) like hctz (hydrochlorothiazide) unless you have a compelling reason eg diabetes, heart disease, kidney disease, etc for something else. Clonidine is far down list. It works but all BP meds work. Down side of Clonidine is rebound hypertension if you forget to take dose. Some find it sedating. Potency depends upon dose. ...Read more

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In 2011 I was in a study (gs-us-248-0120) for hep c. Drugs were tegobuvir, gs5885, gs9451 & ribo. I failed week 2. Am I now resistant to inhibitors?

In 2011 I was in a study (gs-us-248-0120) for hep c. Drugs were tegobuvir, gs5885, gs9451 & ribo. I failed week 2. Am I now resistant to inhibitors?

Probably not: I would certainly get evaluated again by a gastroenterologist, and hopefully start with the new medication combination of sovaldi, Ribavirin and peg-interferon for 12 weeks. >90% "cure" rate. ...Read more

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Is there HIV drug resistance to protease inhibitors?

Is there HIV drug resistance to protease inhibitors?

Yes: The HIV mutates frequently, and when a mutation produces resistance to protease inhibitors this will allow that form of the virus to multiply over other forms which are sensitive. That is one of the reasons for a drug combination which makes single mutational changes less likely to be favorable to the virus. ...Read more

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How could a drug inhibitor be useful in treating cancer?

How could a drug inhibitor be useful in treating cancer?

Need more clarity: Please be more specific...which drug and what inhibitor are you asking about???? tell us what exactly is in your mind. Right now it is not clear to me! ...Read more

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Can you tell me about drugs called renin inhibitors are used to treat hypertension. Explain how they would have this effect.?

Can you tell me about drugs called renin inhibitors are used to treat hypertension. Explain how they would have this effect.?

See below: Here's everything you always wanted to know but were afraid to ask: http://www. Us.elsevierhealth. Com/media/us/samplechapters/9780723431855/9780723431855.pdf ...Read more

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Have any undesirable effects been seen in long term use of the blood pressure drugs of the ACE inhibitor class?

Same as short-term: Analyses have not shown any clear risks, including with regards to risk of cancer. Risks over long-term appear to mimic that seen in short-term use (e.g. Risk of hi potassium, kidney function abnormalities); sometimes this can show up after years on the medicine. There may even be benefits to chronic use (apart from intended benefits), such as lower risk of diabetes or atrial fibrillation. ...Read more

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What medical information/product training are oncologists and gynecologists given before they prescribe a drug such as an aromatose inhibitor?

What medical information/product training are oncologists and gynecologists given before they prescribe a drug such as an aromatose inhibitor?

Varies: Usually, drugs such as aromatase inhibitors are first studied in medical school and then residency. In practice, phsycians study new drugs through continuing medical education courses, physician desk reference, and multiple other sources. ...Read more

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Is buproprion a monoamine oxidase inhibitor (maoi) type of drug?

Is buproprion a monoamine oxidase inhibitor (maoi) type of drug?

No: Bupropion (wellbutrin) inhibits re-uptake of norepinephrine and Dopamine into neurons (nerve and brain cells). It does not inhibit mao, so there are no dietary restrictions or common medication interactions, unlike the the maois. ...Read more

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Sensitive to arbs and allergic to ACE inhibitors, what drug should I take to control my blood pressure?

Diuretic: Start with a diuretic. Hydrochlorothiazide (hctz) is cheap, effective, and well tolerated. Depending on the severity of your hbp, you may require more than 1 drug. Avoid salt and attain/maintain normal weight if you can. ...Read more

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What are the best anti-hypertensive drugs to be given for a patient with hyperlipidemia (beta-blocker vs ACE inhibitor)?

What are the best anti-hypertensive drugs to be given for a patient with hyperlipidemia (beta-blocker vs ACE inhibitor)?

Depends on co-morbid: Depends on other co-morbidities. That is, if hypertensive patient is also diabetic, then ACE inhibitor. If patient is hypertensive and has a history of coronary disease, then ACE inhib and beta-blocker given their secondary benefits, etc. Each patient is unique and the whole pic needs to be considered. ...Read more

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Is there an effective drug of choice for hypertension that is labile and stress related? ACE inhibitors and ARBs don't stop the spikes.

Is there an effective drug of choice for hypertension that is labile and stress related? ACE inhibitors and ARBs don't stop the spikes.

Labile Bp: The life style approaches would be. 1. Try classic transcendental meditation. Works great for some. Get loseit and track salt sodium intake for a week or fitness pal and do both Na and K. If Na>1, 500 mg/ d or K <4, 700 mg /d get DASH EATIMG PLAN. POCKET BOOKS, DASH DIET VGOR HTN. Do chap9 exactly for 2 weeks. Get back with me then. ...Read more

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Is it right to say that there are currently three different effective drugs for depression: tricyclic, oxidace monoamine inhibitors, and prozac (fluoxetine)?

Is it right to say that there are currently three different effective drugs for depression: tricyclic, oxidace monoamine inhibitors, and prozac (fluoxetine)?

Antidepressants: There are multiple types of antidepressants. Tricyclics like imipramine, amitriptylene, desipramine; irreversible maoi's like nardil; mao-b inhibitors -- emsam; ssri's like prozac, celexa, ; lexapro; snri's like effexor, pristiq, (desvenlafaxine) and cymbalta; sari's -- tradozone; nassa -- remeron; ndri -- wellbutrin. So the list is longer than you might have thought, and some classes contain more than I named. ...Read more

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How can the therapeutic effects of antacid drugs, h2 blockers, proton pump inhibitor drugs, misoprostol?

How can the therapeutic effects of antacid drugs, h2 blockers, proton pump inhibitor drugs, misoprostol?

Question?: I'm not sure I fully understand what your question is? The drugs you listed all help with symptoms of GERD or stomach ulcers, and they have different means by which they help patients with these problems. The safest and easiest to take are antacids and H2 blockers. Please consider rephrasing your question more specifically. ...Read more

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Alpha-1 antitrypsin deficiency. Can this relate to high GGT in liver, breathing heart and lung issues, can it affect medications like ACE inhibitors

Alpha-1 antitrypsin deficiency. Can this relate to high GGT in liver, breathing heart and lung issues, can it affect medications like ACE inhibitors

ACE: Is produced in the kidneys and lungs. A-1at deficiency affect the lungs and the liver to cause emphysema and cirrhosis. Due to lung problem, the heart can suffer and symptoms could include tachycardia and heart failure due to the emphysema. It also causes chronic cough. From this you can surmise that yes, GGT can be elevated and ace can decrease but kidney can produce enough. ...Read more