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Doctor insights on: Carbidopa Levodopa Side Effects

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What is the typical starting dose of sinemet (carbidopa and levodopa) for a patient with parkinsons? How long do you need to take it feel its effects? Several weeks?

What is the typical starting dose of sinemet (carbidopa and levodopa) for a patient with parkinsons? How long do you need to take it feel its effects? Several weeks?

Varies: Different movement disorder neurologists have varying treatment regimens, but i prefer to start sinemet (carbidopa and levodopa) at low dosing initially, such as 10/100 3-4 times daily in divided dosing. With your dbs, the regimen may require a different plan. ...Read more

Carbidopa (Definition)

Dopamine is a necessary neurotransmitter in the basal ganglia of our brains, and in parkinson's, there is a deficiency. We supplement l-dopa, to replace, but since the body might break down our oral med, we add Carbidopa which prolongs the benefit ...Read more


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What happens if I take carbidopa and levodopa?

What happens if I take carbidopa and levodopa?

See below: Carbidopa-levodopa is a generic medication for Parkinson's disease and helps dopamine brain connections. Why would you want to take this if you do NOT have Parkinson's?? ...Read more

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How does the drug carbidopa affect levodopa?

How does the drug carbidopa affect levodopa?

Blocks breakdown: Carbidopa acts to block the enzyme aromatic-l-amino-acid decarboxylase which converts l-dopa to dopamine. Since it cannot get into the brain it works in the rest of the body (periphery). When given in combination with l-dopa in parkinson's disease, it inhibits the conversion of l-dopa to Dopamine in the body so that more is available to be converted in the brain where it is needed. ...Read more

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Please describe the medication: sinemet (carbidopa and levodopa)?

Please describe the medication: sinemet (carbidopa and levodopa)?

Carbidopa/levodopa: Sinemet (carbidopa and levodopa) is a combination drug that contains Carbidopa and levodopa. It is most commonly prescribed for parkinson's disease but may also be prescribed for other conditions including restless legs syndrome. ...Read more

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What is the typical dosage of sinemet (carbidopa and levodopa) cr?

What is the typical dosage of sinemet (carbidopa and levodopa) cr?

Sinemet-CR: This has to be determined by careful titration thru your doctor. Initial dose is usually 50-200. Consult your Neurologist. ...Read more

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What does sinemet (carbidopa and levodopa) consist of and what is cr?

What does sinemet (carbidopa and levodopa) consist of and what is cr?

See below: Sinemet® (carbidopa-levodopa) is a combination of Carbidopa and Levodopa for the treatment of parkinson's disease and syndrome.Sinemet® cr (carbidopa-levodopa) is a sustained-release combination of Carbidopa and Levodopa for the treatment of parkinson's disease and syndrome. ...Read more

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I took 9 sinemet (carbidopa and levodopa) tablet a day, is that to much?

Sinemet (carbidopa and levodopa): Not sure what milligram each, but if that's what your doctor prescribed & your symptoms are under control & you are tolerating the medication well, then you should be ok. ...Read more

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What is the maximum dosage per day for Sinemet (carbidopa and levodopa) tablets?

What is the maximum dosage per day for Sinemet (carbidopa and levodopa) tablets?

Variable, but: In my experience, the maximum Sinemet (carbidopa and levodopa) dosing is the 25/250 tab four times daily, and if this seems to wear off, one can add Comtan (entacapone). Problem with going too high with L-DOPA is incidence of dyskinesias. ...Read more

Levodopa (Definition)

A drug which when it gets into the brain is converted to Dopamine that ...Read more