Top
10
Doctor insights on: Carbidopa

Share

Carbidopa (Overview)

Dopamine is a necessary neurotransmitter in the basal ganglia of our brains, and in parkinson's, there is a deficiency. We supplement l-dopa, to replace, but since the body might break down our oral med, we add Carbidopa which prolongs the benefit until the next dose.


1

1
What are dangers for using carbidopa at the age of 50?

What are dangers for using carbidopa at the age of 50?

Not dangerous per se: I presume you mean using sinemet, (carbidopa and levodopa) which is a combination of Carbidopa and levodopa, for parkinson disease. There are no inherent dangers with using this medicine. If, however, the patient is on high doses, the patient will likely develop dyskinesias which are "excess" movements of the patient. Most patients prefer dyskinesias to being frozen, but sometimes the movements can be extreme. ...Read more

Carbidopa (Overview)

Dopamine is a necessary neurotransmitter in the basal ganglia of our brains, and in parkinson's, there is a deficiency. We supplement l-dopa, to replace, but since the body might break down our oral med, we add Carbidopa which prolongs the benefit until the next dose.


2

2
How does the drug carbidopa work?

How does the drug carbidopa work?

Blocks breakdown: Carbidopa acts to block the enzyme aromatic-l-amino-acid decarboxylase which converts l-dopa to dopamine. Since it cannot get into the brain it works in the rest of the body (periphery). When given in combination with l-dopa in parkinson's disease, it inhibits the conversion of l-dopa to Dopamine in the body so that more is available to be converted in the brain where it is needed. ...Read more

4

4
Is carbidopa-levodopa safe for women who are pregnant or breastfeeding?

Is carbidopa-levodopa safe for women who are pregnant or breastfeeding?

Discuss with your MD: Pregnancy cat. C. No teratogenic effects were observed in a study in mice receiving up to 20x the maximum recommended human dose but there are no adequate studies in pregnant women. In individual cases Levodopa crossed the human placental barrier, enters the fetus, and is metabolized. In a study of one nursing mother with pd, excretion of Levodopa in human breast milk was reported. Discuss with md. ...Read more

See 1 more doctor answer
5

5
Does anyone know what side effectcs are if I suddenly stop taking carbidopa?

Does anyone know what side effectcs are if I suddenly stop taking carbidopa?

Usually none: I presume that you are on carbidopa/levodopa (sinemet (carbidopa and levodopa)), probably for parkinson disease or possibly for restless legs. If your dose is not high, you can just stop it. There is a theoretical risk of a bad neurological symptoms if stopping a high dose quickly. If you are taking just Carbidopa , which is sometimes given in pd to help with sinemet (carbidopa and levodopa) nausea, it can be stopped quickly. ...Read more

7

7
How does the drug carbidopa work?

Blocks breakdown: Carbidopa acts to block the enzyme aromatic-l-amino-acid decarboxylase which converts l-dopa to dopamine. Since it cannot get into the brain it works in the rest of the body (periphery). When given in combination with l-dopa in parkinson's disease, it inhibits the conversion of l-dopa to Dopamine in the body so that more is available to be converted in the brain where it is needed. ...Read more

8

8
What is the definition or description of: carbidopa?

What is the definition or description of: carbidopa?

Parkinson's: Dopamine is a necessary neurotransmitter in the basal ganglia of our brains, and in parkinson's, there is a deficiency. We supplement l-dopa, to replace, but since the body might break down our oral med, we add Carbidopa which prolongs the benefit until the next dose. ...Read more

9

9
What are dangers for using carbidopa at the age of 50?

Not dangerous per se: I presume you mean using sinemet, (carbidopa and levodopa) which is a combination of Carbidopa and levodopa, for parkinson disease. There are no inherent dangers with using this medicine. If, however, the patient is on high doses, the patient will likely develop dyskinesias which are "excess" movements of the patient. Most patients prefer dyskinesias to being frozen, but sometimes the movements can be extreme. ...Read more

10

10
Does anyone know what side effectcs are if I suddenly stop taking carbidopa?

Usually none: I presume that you are on carbidopa/levodopa (sinemet (carbidopa and levodopa)), probably for parkinson disease or possibly for restless legs. If your dose is not high, you can just stop it. There is a theoretical risk of a bad neurological symptoms if stopping a high dose quickly. If you are taking just Carbidopa , which is sometimes given in pd to help with sinemet (carbidopa and levodopa) nausea, it can be stopped quickly. ...Read more