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Doctor insights on: Cancer Treatment With Taxol Zoloda

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How can Taxol (paclitaxel) affect cancer cells?

How can Taxol (paclitaxel) affect cancer cells?

Taxol (paclitaxel): ...Works in cellular organelles called microtubules, which are the structures that separate the chromosomes during cell division. Taxol (paclitaxel) stabilizes the tubules and interrupts the normal cellular division process.

Dr. Barry Rosen
4,323 Doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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How does Taxol (paclitaxel) treat cancer?

How does Taxol (paclitaxel) treat cancer?

Inhibits division: Taxol (paclitaxel) is a chemotherapy drug that inhibits microtubules. This ends up inhibiting cell replication thereby making it difficult for cancer cells to continue dividing.

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How can Taxol (paclitaxel) against the cancer?

How can Taxol (paclitaxel) against the cancer?

Kills cancer cells: Plclitaxel (taxol (paclitaxel)) originally isolated from yew plant, inhibits cell division (mitosis) normal perfect spindle assembly before it divides, is changed by Taxol (paclitaxel) cell will not proliferate and dies. It will do the same to normal cell also, you need expert oncologist to give a calculated dose to kill cancer cells only.

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What is the difference between gemzar (gemcitabine) & taxol? I have three stage 4 cancers.

What is the difference between gemzar (gemcitabine) & taxol? I have three stage 4 cancers.

Side effects vary: Gemzar (gemcitabine) is generally well tolerated given weekly 2 out of 3 or 3 out of 4 weeks per cycle. Usually does not cause hair loss or neuropathy. Taxol can be given weekly or every 3 weeks and with risk of reactions during infusion (steroid premedication needed), some hair loss and significant neuropathy.

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How effective is Paclitaxel (Taxol) for treating lung cancer?

How effective is Paclitaxel (Taxol) for treating lung cancer?

Some prolongation: • A large array of chemo agents are utilized in the treatment of non small cell Ca of lung. While Taxol is one of the primary agents, the Platinum agents such as Cisplatin, Carboplatin, Gemzar and Camptosar (irinotecan) are given alone or in combination with. Taxol. Because of the presence of malignant stem cells, resistant to chemo survival is in months. With immunochemo therapy survival improved.

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Would I benefit from Taxol (paclitaxel) if I have breast cancer?

Would I benefit from Taxol (paclitaxel) if I have breast cancer?

Depends: ...On the stage and characteristics of the cancer and your general health. Taxol (paclitaxel) is a good drug, very beneficial for early stage and advanced cancer but I cannot tell you a definite answer without more info.

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Any ideas why Taxol (paclitaxel) (for cancer patients) affects the bone joints?

Yes, I have some ide: Taxol is known to cause some aches and pains. They are called myalgia/arthralgias which are typically seen about one week after the injection and usually last no more than 3-4 days after each dose. They can be managed easily with use of tylenol (acetaminophen). Sometimes patients need a NSAID to control them in case tylenol (acetaminophen) fails to help and control them adequately.

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AFTER taxol/A/C for breast cancer stage2, path result-Lympho vascular invasion-shouldn't chemo resolved this? What now?

AFTER taxol/A/C for breast cancer stage2, path result-Lympho vascular invasion-shouldn't chemo resolved this? What now?

Ask your oncologist!: You need to givel us more information...Did the tumor shrink on chemotherapy? How much. Shrinkage? If the tumor did not shrink much, that is a bad sign. But if it reduced in size substantially then you are on the right track. But your oncologist can address your questions and guide you better.

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After taxol (paclitaxel) reaction for 3b squamous nsclc, husband is on weekly treatment, 2 wks abraxane, then 1 w/ abraxane/carboplatin. Is it normal & effective?

Yes its a good alter: If your husband has allergy to Taxol, (paclitaxel) then using Abraxane as an alternative is a good decision. This treatment works well in about half (50%) of the patients, not in the others. You will know within 6 to 8 weeks of chemotherapy treatments.

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Can the reoccurance of cervix cancer within pelvis be cured with chemo[carboplatin+taxol]?

Can the reoccurance of cervix cancer within pelvis be cured with chemo[carboplatin+taxol]?

Ask your Oncologist: This is a question patients often ask their oncologists when he/she recommends chemotherapy. So you should ask and see the answer you get. Then we can also verify it for you, if needed.

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Stage 2B idc breast cancer-neoadjuvant. .. Had taxol/herceptin (trastuzumab) for 16wks. Now a/c chemo. Is it risky to be without herceptin (trastuzumab) until surgery in jan?

Stage 2B idc breast cancer-neoadjuvant. .. Had taxol/herceptin (trastuzumab) for 16wks. Now a/c chemo. Is it risky to be without herceptin (trastuzumab) until surgery in jan?

Should be okay: You are receiving ac now and I think (and I hope) it should take care you cancer well --to shrink it down further- so you can have surgery in january. It is not safe to combine adriamyicn and Herceptin (trastuzumab) as it could give you significant problem with your heart. Once you are done with surgery- you will need Herceptin (trastuzumab) to be continued for 1 year.

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Estrogen receptor ER positive breast cancer adjuvant Taxol (paclitaxel) benefits?

Estrogen receptor ER positive breast cancer adjuvant Taxol (paclitaxel) benefits?

Get Oncotype: In order to answer this question, more details are needed (size of tumor, lymph node involvement, etc). A test that will help to decide if you need chemotherapy or not is the oncotype dx. I highly recommend you speak with your oncologist and even consider a 2nd opinion.

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Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C, lumpectomy, rads, lymphovascular invasion. What does this mean for prognosis & follow up?

Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C, lumpectomy, rads, lymphovascular invasion. What does this mean for prognosis & follow up?

Prognosis fair: Stage IIb breast cancer is usually palpable at 2-5 cm. And at time of procedure to remove lesion, sentinel nodes are + suggesting axillary dissection and reason for neoadjuvant therapy. Lymphovascular invasion increases chance for recurrence. With Her2+ Herceptin (trastuzumab) with chemo should be used and PET/CAT needed to assure met foci not missed in distal organs. Carful follow up needed.

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Husband is being put on carboplatin/arbraxane for 3b squamous nsclc, after taxol (paclitaxel) reaction. Concurrent radation therapy. Is this an effective plan?

Yes it is!: This is the current recommended chemotherapy (along with concurrent radiotherapy) treatment plan. Hopefully it should work well. But it will take 6-8 weeks to see the full benefit.

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Why is it that the same cancer treatment doesn't work for everyone?

Why is it that the same cancer treatment doesn't work for everyone?

Genetically differen: Cancer is a disease caused by bad genes but everyone's genes are different. So there are no two individuals whose cancers are entirely alike even with the same/similar diagnosis.

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Why doesn't cancer treatment end after remission is achieved?

Why doesn't cancer treatment end after remission is achieved?

Which cancer?: Adjuvant (post surgery) treatment does have an end. Some metastatic treatments usually end at a maximum number of cycles of therapy (eg lung cancer - 6). Some treatments are continued in the advanced/metastatic setting until progressive disease or toxicity because they have been proven to (or thought to) improve survival.

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How can I enjoy sex after cancer treatment if I can't have penetrative intercourse?

How can I enjoy sex after cancer treatment if I can't have penetrative intercourse?

Incomplete info: From the information provided, it is not feasible to know why you cannot have penetrative intercourse. Sexual satisfaction may be possible even if penetration is not practical. To provide a more meaningful suggestion, one would need to address specific issues through physical examination and discussion. Please raise the issue with your doctor.

Dr. Michael Thompson
190 Doctors shared insights

Cancer Treatment (Definition)

Cancer is a very broad term for all types of solid and blood malignancies. The treatments vary by biology, research and phase of ...Read more