Doctor insights on:
Cancer Ibd Patients
Not always.: Early in colon cancer, there are typically NO symptoms until the cancer tumor grows large enough that it begins to cause problems in the digestive tract. Small, asymptomatic cancers can be found by screening colonoscopy. Larger tumors may cause changes in bowel habits (diarrhea/constipation/change in consistency of stool), blood in stool, unexplained weight loss, weakness/fatigue, persistent pain ...Read moreSee 2 more doctor answers
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Not directly usually: There is debate about how closely these 2 cancers are related. Both have hereditary natures and are more common generally in obese patients. Both often begin with more benign precursor lesions like dcis for breast cancer and benign polyps for colon cancer. Both are very common but there is little evidence that having either predisposes to having the other. ...Read moreSee 2 more doctor answers
Yes: Ulcerative pancolitis, is a chronic disease that inflames the gastrointestinal (GI) system. Specifically, ulcerative colitis causes lesions in the colon. With the inflammation there is a higher risk for developing CRC. Two factors associated with cancer risk , is disease duration and extent of colon involvement . Early tumors develop denovo from carcinogens and utilize inflammation to progress ...Read more
No: Colon Cancer is induced for the most part in non hereditary disease by viral transfection. The most common organism is the polyoma virus. Ovarian cancer is not derived from this viral event. Colon cancer begins in the mucosa of the bowel where ovarian Ca is an epithelial disease similar to that of peritoneal carcinomatosis. The only relationship is when colon metastasizes to ovary. ...Read moreSee 2 more doctor answers
What percentage of ppl with UC get colon cancer? are colon cancer statistics the same for ppl who have mild colitis?
Duration dependent: Colorectal cancer risk 5 to 10 percent after 20 years and 12 to 20 percent after 30 years of disease. Also depends on extent of disease. This with disease proximal to hepatic flexure have a greater risk than those with left colon involvement only. (UpToDate) Thanks for trusting HealthTap! ...Read more
Immunochemotherapy: When FOLFOX therapy (chemotherapy) has failed Immune reactive agents i.e. Avastin for blood vessel growth and Erbitux for epidermal growth factor have been applied as well as agents affecting tyrosine kinase. The Immunogenic protein that acts as a vaccine isolated, a is a byproduct of oncofetal protein MUC5ac in its post translational form. In stage IV used to produce mAbs for strong ADCC. ...Read more
Genetic mutations: HNPCC or hereditary nonpolyposis colorectal cancer is an autosomal dominant genetic condition that has a high risk of colon cancer The disease first described by Lynch and is associated with other cancers including endometrial ovary and stomach. The increased risk is due to inherited mutations that impair DNA mismatch repair. .Individuals with HNPCC have an 80% lifetime risk for colon ca. ...Read more
What percentage of lynch syndrome patients develop colon polyps by age 60? Not cancer but just polyps
Colon ca, not polyps: Lynch syndrome affects a minority of patients, as it is a rare condition that is often inherited (in about 30% of pts). Of these pts, about 70% will develop colon cancer - most of them by age 60. The risk is high. But the syndrome causes NON-polyp colon cancer, not polyps. It usually requires colon removal (colectomy) to reduce risk. Use HealthTap Prime or talk to your gastroenterologist about sym ...Read more
It depends ... : Dysphagia is a common side effect with many chemo therapeutic regimens. Some treatments can decrease a patient's ability to fight off fungal and bacterial overgrowth in the mouth and digestive systems. The diagnosis of this isn't usually difficult and can in many cases be treated with medications. ...Read moreSee 1 more doctor answer
Can be the same: The intestines are a group of structures including stomach, small intestine and large intestine (which is the colon). Cancers can form in any of these sites, but large intestine (colon) cancer is most common. So colon cancer is a type of intestinal cancer. ...Read moreSee 2 more doctor answers
Depending how used: CEA first identified in 1965 by Phil Gold and Samuel O. Freedman in human colon cancer extracts. Thought to be valuable for dx colorectal Ca but the glycoprotein is also expressed in inflamed tissue so that smoking and enema can cause rise. Best used for monitoring so that if present in primary and rises it represents treatment failure and if diminishes during treatment it represents a response. ...Read moreSee 5 more doctor answers
I : I wish there were a reliable cure for stage IV colon cancer, but unfortunately there is not, and vitamin b17 is most definitely not one. Vitamin b17 is another name for laetrile. This named was coined in the 50's in an attempt to overcome drug regulations and increase sales based on the popularity of vitamins. Laetrile, or amygdalin as it is also called, is not a vitamin by any definition of the biochemical term. There is no scientific evidence that laetrile or vitamin b17 has any anti-cancer benefits. I share many patients with naturopathic oncologists who prescribe nutritional and herbal therapies, but i've yet to see any of them consider laetrile effective. In the very special circumstance when a stage IV colon cancer patient has only a small number of metastasis in the liver only, there is a possibility of being cured by a combination of surgery and other therapies. Most of the time in stage IV disease, the cancer has spread widely in the body and it is impossible for the body or doctors to get rid of every last bad cell. There are however, many new and effective treatments that have significantly lengthened the amount of time patients with this disease can live and with a good quality of life. Some of these treatments are chemotherapy. Many people forget that one of the most effective chemotherapy drugs for colon cancer, irinotecan (camptosar), is a slightly modified form of a compound originally found in the bark of the "happy tree" (camptotheca) which grows in southern china. Other effective treatments are special purified antibodies (which are part of our immune system). One class of these antibodies attack specific changes in the cancer cells that distinguish them from normal cells and can stop the cancer cells from growing so fast. Another class of these antibodies help stop the cancer cells from hijacking the normal body to build new blood vessels to feed the cancer. More information can be found via the links below. I wish you or your loved on the best in their struggle with colon cancer. ...Read moreSee 2 more doctor answers
Increased with time: Colon ca risk is increased in ulc colitis (uc) and crohn's colitis (cd). Risk increases by .5-1%/yr above general public, after 8-10 years after diagnosis. Small bowel cd has increased risk of small bowel ca; cd has increased risk lymphatic ca (lymphoma). Generally recommend annual colonoscopy/biopsy after 8-10 years of disease. Risk ca increased more in diffuse uc vs. Left sided disease. ...Read moreSee 1 more doctor answer
Could a positive FIT test (occult blood) in 23 yr old mean IBD? I'm obviously too young for polyps/cancer.
Will a video colonoscopy completely rule out crohans disease, ulcerative colitis and other ibd. Will it also rule out cancer?
Not all: Colonoscopy will rule out colon cancer , ulcerative colitis , ( early uc in remission may not show the disease ) but not crohn's involving only small bowel only , other ibd some times may not have visible pathology . All of these diseases need biopsy as a proof. ...Read moreSee 1 more doctor answer
What would cause a rectovaginal fistula, not related to birth or ibd.. I have one and don't know why? Please help.. Worried I have cancer
I have diarrhea for around 20 days now got fecal calprotectin 77ug/g should I be worried abt cancer or ibd?
IBS VS IBD: Given the duration of your symptoms , you need a prompt reevaluation. Exam and labs. Especially stool for O& P, Giardia , c diff , isospora, cryptosporidium. And h pylori. A Gi cosult for colonoscopy an endoscopy. While you are getting things set up , you should move to a gluten free diet Wholeapproach.com and gutbliss.com. They will do biopsies to evaluAte for cancer and IBD and celiac. ...Read more
What are the chances this is colon cancer? Loose bloody stool. 25 year old male with history of ibd. Seeing a GI doc soon.
Is elevated lipase associated with early lung cancer? I know amylase is, but my amylase is normal.. I also know elevated lipase is associated with pancreatitis, cp, celiac disease, ulcer, ibd
Can cancer look like internal hemmorhoids on colonoscopy? Fecal calprotectin is high (250) but biopsy showed no IBD. Stomach cramps too. Misdiagnosed?
INTERNAL hemorrhoids look like INTERNAL hemorrhoids nothing else!.....have a frank discussion with your treating Health Care Provider about your concerns...they may be contributing to your GI symptoms!,,,Hope this is helpful...
Dr Z ...Read more
I am having a CT colonography due to chronic constipation & pencil stools. Will this show IBD, such as Crohn's/Colitis as well as colon/rectal cancer?
CT resolution : CT examination illustrates the anatomy of a part of the body, the lay of the land. The functionality of the lining of the wall is best illustrated by a colonoscopic exam. Talk to your doc about why he is doing any given exam on you. ...Read more
Smoke/alco free 15 months. New labs show high ldh + lipase; borderline low amylase + globulin. Already ruled out ibd, celiac, mono, hep, hiv, tb, lupus, ra. July ct=normal liver/kidneys/panc. Cancer?
MRCP: Looks like you have pancreatitis, but if you have not had alcohol, need mrcp to see if there any pancreatic duct abnormalities. Need more info, were you drinking before and did you have multiple pancreatits before? Mrcp followed by eus would help. Ercp may be needed once acute episode is resolved, or if you find any stricture in the duct. ...Read moreSee 1 more doctor answer
Wide variety: Ibd is a spectrum of diseases that includes crohn's disease, ulcerative colitis and indeterminate colitis. These disease may vary in their distribution and associated symptoms. Because it represents inflammation of the GI tract - and pain, diarrhea, bleeding and wt loss is common. It can also have extra intestinal manifestations - skin, eyes, joints, liver. ...Read moreSee 1 more doctor answer
IBD : You didn't mention which ibd you have? Crohn's disease or ulcerative colitis! how long you have the disease? I don't see you taking any medication, at least not from this history. Are you on remission or relapse? Why do you want surgery? Please leave up to your doctor, who is treating you, to decide when you need surgery. Some have good result and some don't. Good luck. ...Read moreSee 1 more doctor answer
Ibd patient on prednisone for 4 mos MRI now shows osteonecrosis is this reversible or how is it treated now off prednisone will it continue worsening?
It is not reversible: Osteonecrosis actually denotes death of bone. It is not uncommon that with prolonged cortisone use osteonecrosis of bone may occur it is most often seen in the hip. Once it develops it is not reversible. It often leads to chronic pain and may ultimately cause painful arthritis. In its end stages joint replacement may be needed. ...Read moreSee 1 more doctor answer
Rectal bleeding for 5 months, sent to GI doctor. told its normal for IBD patients. i asked if its hemorrhoids, they said unlikely. i dont know where the bleed is, isnt anyone supposed to physically check to see if it is hemorrhoids or something else?
It depends...: Apparently you mean IBD (inflammatory bowel disease, i.e. ulcerative colitis, Crohn's disease), not IBS (irritable bowel syndrome). IBS doesn't bleed, IBD often does. Need for internal exam (e.g. proctoscopy) depends mostly on amount of blood, changing symptoms, etc; maybe no need if no recent change. This sounds mostly like a doctor-patient communication problem. Ask again or get 2nd opinion. ...Read more
Risk Factor For: Depending on the extent of disease, after 10 -15 years of either ulcerative colitis or crohn's (newer data also links crohn's) - they are considered risk factors for disease. Individuals with long standing ibd are at increased risk for colon cancer and other illnesses. ...Read moreSee 3 more doctor answers
No!: We can't always cure cancer, but we can always treat pain. Cancer patients should never suffer from pain. We can block nerves that carry pain signals, use medications, and even implant spinal cord stimulators to control pain. Cancer patients die for many reasons, but not from pain. If you are suffering from cancer pain, ask your doctor for relief. And don't stop asking until you are comfortable! ...Read more
Cancer: Love, compassion, tolerance, and most important empathic listening, being able to understand the unique experience of the person suffering without trying to fix or judge. Also helping the person live life despite cancer. Helping the person to participate in life as much as possible. ...Read moreSee 1 more doctor answer
Gluten and Cancer: In my opinion gluten is "bad" for everyone. It is known to increase permeability of the gut, which affects the immune system. Cancer is at least partially an immune problem, so that is bad. I'm sure some others may disagree with me, but I do have lots and lots of training in functional medicine and addressing root causes of problems, including cancers, gluten effects, and immune issues. ...Read moreSee 1 more doctor answer