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Doctor insights on: Cancer Antigen Ca 125

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Dr. Barry Rosen
4,369 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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35y stage i rectal cancer cured via lar w/ tme & wide margin, post-op biopsy clear of cancer in all 17 lumph nodes. Advice on follow-up & gene tests?

35y stage i rectal cancer cured via lar w/ tme & wide margin, post-op biopsy clear of cancer in all 17 lumph nodes. Advice on follow-up & gene tests?

Regular Surveillance: Regular surveillance with physical exam, rectal exam and cea levels on a yearly basis will help detecting future recurrence or new cancers. Colonoscopy is recommended when any of the above are positive. Hope this will help. ...Read more

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Will cancer always cause an elevated CRP & ESR? Throat cancer, lymphoma?

Will cancer always cause an elevated CRP & ESR? Throat cancer, lymphoma?

No: Elevated ESR and CRP are markers of inflammation, not cancer. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, low fat milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more

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My pet scan was highly suspicious for malignancy in rt lung.Now onto Bronchoscope so didn't pet confirm cancer?This cancer isn't curable!

My pet scan was highly suspicious for malignancy in rt lung.Now onto Bronchoscope so didn't pet confirm cancer?This cancer isn't curable!

PET scan helps but n: A PET scan can show an abnormality where body cells are overactive. This happens commonly with Cancer and with any Infection or inflammation. So a biopsy is required to make the distinction between Inflammation and Cancer. A bronchoscopy may show the tumor or it may be used to get a biopsy by getting near to the tumor ...Read more

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Colon cancer, primary removed . Now 1 liver met , 1 node n 1 aortocaval nodule . Chemo irinotecan n Xeloda (capecitabine) has not worked. Wats survival few years?

Colon cancer, primary removed . Now 1 liver met , 1 node n 1 aortocaval nodule . Chemo irinotecan n Xeloda (capecitabine) has not worked. Wats survival few years?

Survival is less 6+m: Liver spread could be burnt off-radiofrquency ablation. The aortocaval nodule could not be removed except surgically. You 4th stage. survival is one to two years. ...Read more

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How is ecog ps2 related to small cell lung cancer?

How is ecog ps2 related to small cell lung cancer?

Not directly: Ecog ps (performance status) refers to the functional status of patients with cancer (any type, not just small cell). Ps 2 describes pts that " are ambulatory and capable of all selfcare but unable to carry out any work activities. Up and about more than 50% of waking hours" ps scores are used to decide how intense of treatment cancer patients should undergo. ...Read more

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I'm concerned about prostate cancer metastasis. Where can prostate cancer spread?

I'm concerned about prostate cancer metastasis. Where can prostate cancer spread?

In theory, prostate cancer cells can spread anywhere in the body: In practice, though, most cases of prostate cancer metastasis occur in the lymph nodes and the bones. Prostate cancer metastasis occurs when cells break away from the tumor in the prostate. The cancer cells can travel through the lymphatic system or the bloodstream to other areas of the body. More commonly prostate cancer metastasis can occur in the: Bones, Lymph nodes, Lungs, Liver, Brain. Rare locations of prostate cancer metastasis include: Adrenal glands, Breasts, Eyes, Kidneys, Muscles, Pancreas, Salivary glands, Spleen. If you've been diagnosed with prostate cancer and you're concerned about prostate cancer metastasis, talk with your doctor about your risk of prostate cancer metastasis and your treatment options. ...Read more

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Am 32 - no children yet. Best way to determine 1.Ovarian cancer-pap smear or ca 125 & 2.Breast cancer-mammography or ca 15-3 granny died of ovarian ca?

Am 32 - no children yet. Best way to determine 1.Ovarian cancer-pap smear or ca 125 & 2.Breast cancer-mammography or ca 15-3 granny died of ovarian ca?

Exam: I would not recommend obtaining a ca-125 as it is a nonspecific test in patients without ovarian cancer. I would recommend a gynecologic exam. At your age, i would recommend a yearly breast exam. I would start obtaining mammograms at age 40. Hope this helps. ...Read more

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I have had appendix cancer that spread & thyroid cancer. My dad had pancreatic cancer. I am curious about men1/2 & endocrine cancers. I'm only 37...?

I have had appendix cancer that spread & thyroid cancer. My dad had pancreatic cancer. I am curious about men1/2 & endocrine cancers. I'm only 37...?

Probably not: Appendix cancer is not part of any men syndrome. Pancreatic cancer can be, but it is a specific type called a neuroendocrine tumor. Likewise, the thyroid cancer in men syndromes is called meduallry carcinoma, which make up only about 10% of all thyroid cancers. ...Read more

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Seminoma tumour - testicular cancer, what to do?

Seminoma tumour - testicular cancer, what to do?

Orchiectomy: Lesion requires resection by orchiectomy with spermatic cord. Prior to this PET/CAT helpful since this tumor spreads quickly to para aortic nodes and may require chemo or RT depending on node size followed by chemotherapy. Cure rate high for this type of germ cell lesion. ...Read more

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Is the kras gene behind pancreatic cancer & mucinous borderline malignant tumors? My aunt died from pancreatic this yr & i had the mucus tumor-*stg 1a

Is the kras gene behind pancreatic cancer & mucinous borderline malignant tumors? My aunt died from pancreatic this yr & i had the mucus tumor-*stg 1a

Two different types: Your aunt had the garden variety pancreatic cancer, your own tumor was different and it has a much better prognosis than your aunt's cancer. Ras gene is often mutated in pancreatic cancer but, as of now, it has no impact on diagnosis or on treatment of pancreatic cancer. ...Read more

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Is chemotherapy required for stage 1A IDC breast cancer, tumor size 1.1 cm, ER & PR positive, HER2 negative, nuclear grade 1. Patient is 42 years old.

Is chemotherapy required for stage 1A IDC breast cancer, tumor size 1.1 cm, ER & PR positive, HER2 negative, nuclear grade 1. Patient is 42 years old.

Borderline call!: Your breast tumor is quite small, so it has >90% odds that it can be safely treated with surgery, without any chemotherapy required. You may ask your doctor for treating you with tamoxifen which is a antihormone type of medication, commonly used as the treatment for tumors that are ER positive. Good luck ...Read more

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My dad died of cancer that spread from his lip to lymph nodes to lung 47yo, gpa died of prostate cancer 79yo. Any studies linking cancer to genetics?

My dad died of cancer that spread from his lip to lymph nodes to lung 47yo, gpa died of prostate cancer 79yo. Any studies linking cancer to genetics?

There are: There are several cancers that area related to genetics. The are about 5-15% of cancers. The bulk are not. In your case the key question is if your father was a smoker or not. This kind of cancer is not usually related to prostate cancer. The other important thing is that your mother's family history also is equally important as your father's. ...Read more

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Dr. James Lin
128 doctors shared insights

Ca125 (Definition)

Ca-125 (cancer antigen 125 or carbohydrate antigen 125) is a biomarker/tumor marker for ovarian cancer (etc); however, it is not sensitive or specific enough to use as a screening test. Also, a uk study showed that treating based on ca125 level did not improve outcomes. "125" comes from the 125th attempt to develop a marker. It was introduced by bast ...Read more


Antigen (Definition)

Antigens are chemicals which upon exposure to the surface or inside of the body, will cause a reaction term allergic. Many substances will do this and allergic response is the basis for immunological protection for ...Read more