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Doctor insights on: Can Zoloft Cause Depression

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If Zoloft (sertraline) is helping reduce my pain, does this suggest my pain is caused by my anxiety/depression ?

If Zoloft (sertraline) is helping reduce my pain, does this suggest my pain is caused by my anxiety/depression ?

Not necessarily: Zoloft (sertraline) is an SSRI type of drug. This class of medications, though primarily used & indicated for treating depressive mood disorders & related psychiatric phenomenon, also has analgesic properties. PLEASE-Don't misinterpret what I say by thinking you can use Zoloft (sertraline) like aspirin or hydrocodone...YOU CAN'T but over the long haul these medications can alter pain reception & this is independent of mood ...Read more

Dr. Pamela Pappas
4,494 doctors shared insights

Depression (Definition)

Depression is a mood disorder that can affect behavior and emotions. Symptoms of depression include feeling down most of the time, losing interest in previously enjoyable activities, increase or decrease in appetite or weight, sleeping more or less, becoming easily agitated or lethargic, feeling worthless, feeling guilty, having difficulty concentrating, thinking more about death and dying. Depression can sometimes result in suicidal thoughts and plans. In this case, emergent ...Read more


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I have been on toprol (metoprolol) for BP and Zoloft for depression for about 15 years. In the last year I an experiencing extremem fatibue. One of my dr's say they cause fatigue and switched me to priivid but it doesn't work. Any suggestions?

I have been on toprol (metoprolol) for BP and Zoloft for depression for about 15 years. In the last year I an experiencing extremem fatibue. One of my dr's say they cause fatigue and switched me to priivid but it doesn't work. Any suggestions?

Viibryd (vilazodone hydrochloride): Fairly new antidepressant made by forest labs, same company that made Celexa & lexapro. I note similar results on low dose of viibryd (vilazodone hydrochloride). Talk to your doctor about dose or switch, due to lack of response, assuming you tried viibryd (vilazodone hydrochloride) long enough. ...Read more

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Can someone tell me between zoloft, (sertraline) Prozac and celexa which one treats depression and OCD better? And which one will not cause weight gain the best.

Can someone tell me between zoloft, (sertraline) Prozac and celexa which one treats depression and OCD better? And which one will not cause weight gain the best.

Medications: That is not how medicine works. They all are very effective and used for a variety of different reasons. The best drug for you is the issue and that is determined with the physician working with you in person. ...Read more

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Does Zoloft (sertraline) make you gain weight? I'm taking 100 MG for depression.

Does Zoloft (sertraline) make you gain weight? I'm taking 100 MG for depression.

SSRI can add weight: SSRI such as ZOLOFT (sertraline) are commonly prescribed antidepressants because they have been shown to be effective and are generally well tolerated but not side effect free. Weight gain is not uncommon. Speak to your doctor.Together you may decide it is advisable to adjust your medications and/or to add a form of therapy to your treatment plan.Good luck. ...Read more

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I'm taking redotex for lose weith, and Zoloft (sertraline) 50mg for depression, is this safe?

Maybe not: redotex? Is there a generic name? Is this an over the counter weight loss pill? If so, it's effects usually only limited and temporary, and it's not safety tested/regulated by proper authorities, likely. Possible interaction with Zoloft (sertraline) or any medication. Change your lifestyle instead. Eat healthier and move more, and you can then also get off the Zoloft (sertraline), possibly. Good luck. ...Read more

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Can i safely take 400mgs of zoloft (sertraline). I'm currently taking 200 - 300 mgs daily. My depression varies and today its bad?

Please don't up your: Dose dependent on how you feel one day. It takes quite a while for serotonin levels to increase - so upping your dose for a day will not make symptoms better. 400 mg of zoloft (sertraline) is well above the recommended dosage. You need to discuss this with your psychiatrist/ physician. See that you drink socially - that is definitely contraindicated if you take zoloft (sertraline). ...Read more

See 2 more doctor answers
Dr. Donald Jacobson
1,041 doctors shared insights

Sertraline (Definition)

Also called zoloft, (sertraline) is one of selective serotonin reuptake inhibitors, with antidepressant/anti-anxiety actions. May cause headaches, nausea & ...Read more


Dr. Alan Ali
993 doctors shared insights

Zoloft (Definition)

Zoloft is a serotonin reuptake blocker which is a kind of ...Read more