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Doctor insights on: Can You Take Singulair And Benadryl Together

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Dr. John Chiu
1,049 Doctors shared insights

Diphenhydramine (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


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Can my son take Benadryl (diphenhydramine) right now while taking Singulair? He takes Zyrtec also but we're out & he's suffering big time!! He's 13, 120 pounds.

Can my son take Benadryl (diphenhydramine) right now while taking Singulair? He takes Zyrtec also but we're out & he's suffering big time!! He's 13, 120 pounds.

Yes: It is safe for him to take Benadryl (diphenhydramine) with Singulair. Based on his weight he can take 50mg every 6-8 hours. It potentially can make him drowsy. All the best and I hope he feels better. ...Read more

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I'm having an allergy attack. I'm already prescribed Zyrtec and Singulair and still can't stop sneezing. Can I take Benadryl with these 2 meds and go to bed?

I'm having an allergy attack. I'm already prescribed Zyrtec and Singulair and still can't stop sneezing. Can I take Benadryl with these 2 meds and go to bed?

Allergy meds: Yes - there should be no reaction with the singulair and maybe a slight reaction (increased somnolence)the the zyrtec but since you are heading to bed that isn't an issue. You might want to double the dose of Zyrtec going forward as the 20 mg dose was actually better when the drug was being developed. ...Read more

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My 4 year old takes zyrtec 1 tsp and singulair 4mg every night. She got a couple mosquito bites yesterday and they are swollen. Can she have a dose of benadryl also tonight? Her left eye has also been watering for several days even with both allergy meds.

My 4 year old takes zyrtec 1 tsp and singulair 4mg every night. She got a couple mosquito bites yesterday and they are swollen. Can she have a dose of benadryl also tonight? Her left eye has also been watering for several days even with both allergy meds.

Allergy: A one time dose should be OK. Diphenhydramine is short acting while Zyrtec is long acting. So, there will be some overlap, but short lived. Adding Zantac (ranitidine) also helps improve the symptoms faster since the two groups of medications have a synergistic effect. ...Read more

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I take zyrtec and singulair (montelukast) daily in the morning. Is it ok to take benedryl also, in the evening, while visiting friends with pets for the weekend?

Yes you can: You can take extra Benadryl (diphenhydramine) but it would make you drowsy so you should not drive. If those do not help, you might need to seek help from a local allergist. ...Read more

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I have asthma & severe allergies, currently taking zyrtec, singulair (montelukast) and albuterol as needed. We are trying to conceive & I know antihistamines dry up mucus, what can I do to help my mucus in uterus?

I have asthma & severe allergies, currently taking zyrtec, singulair (montelukast) and albuterol as needed. We are trying to conceive & I know antihistamines dry up mucus, what can I do to help my mucus in uterus?

Complicated: Antihistamines can all interfere with ovulation by blocking the action of histamine, a chemical that also plays a role in releasing an egg from the ovary and implanting it in the womb. These drugs are effective at relieving the symptoms of an allergic reaction, but they may also halt conception. If you’re trying to get pregnant, it’s best to avoid antihistamines from mid-cycle until your period. ...Read more

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My daughter is taking montelukast and Qvar daily at night. She is 6 and has asthma. Can she take Benedryl at night for runny nose and terrible cold?

My daughter is taking montelukast and Qvar daily at night. She is 6 and has asthma. Can she take Benedryl at night for runny nose and terrible cold?

Met: Upper respiratory infections may cause worsening of asthma and an increased need for Albuterol.
Cold remedies are often not very useful, but nasal saline rinses and a vaporizer may help to relieve nasal symptoms. If she is allergic and being treated with an anti histamine, this can be continued. ...Read more

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Can you take meloxicam and Benadryl together?

Can you take meloxicam and Benadryl together?

Should be ok if...: If a person had no problems taking meloxicam (Mobic) in the past for some medical condition, and separately had no problem taking diphenhydramine (Benadryl) in the past, then she should be ok taking the medications at the same time. If worried, she can ask her doctor who prescribed the meloxicam. Benadryl does cause drowsiness, so can be unsafe for certain activities such as driving or piloting. ...Read more

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Can I take allegra and Benadryl (diphenhydramine) together?

Can I take allegra and Benadryl (diphenhydramine) together?

Yes, but why: Allegra (fexofenadine) and Benadryl (diphenhydramine) are both antihistamines. Allegra doesn't cross into the brain, so no sedation. Benadryl commonly causes sedation. Typically there is no advantage to taking the 2 together, but also there is no harm at usual doses. ...Read more

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Can you take allegra and Benadryl (diphenhydramine) together?

Can you take allegra and Benadryl (diphenhydramine) together?

2 antihistamines: At usual doses, there should not be significant side effects from taking these 2 antihistamines together. If a person is needing this much for relief, consider seeing an allergist for an evaluation. ...Read more

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Could I take Benadryl (diphenhydramine) and tagamet together?

Could I take Benadryl (diphenhydramine) and tagamet together?

Yes.: However, tagamet (cimetidine) is an unusual medication these days; other acid reducers work longer in smaller doses. ...Read more

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Can I take Mucinex dm and Benadryl (diphenhydramine) together?

Medician Question: This combination could make you very sleepy so be careful - in some cases there could be serious consequenses. See your doctor for more definitive treatment of your cough. ...Read more

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Can you take Benadryl (diphenhydramine) and Claritin together?

Can you take Benadryl (diphenhydramine) and Claritin together?

Antihistamines: They are both antihistamines, so I wouldn't take them together. They both act similarly, so their effect would be too much together. Wait until one wears off before trying the other, about 24 hours or so. ...Read more

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Is it okay to take delsym and Benadryl (diphenhydramine) together?

Is it okay to take delsym and Benadryl (diphenhydramine) together?

Delsym (dextromethorphan): This is an over-the-counter cough medicine which contains dextromethorphan which can be habit-forming if used on regular basis. Benadryl (diphenhydramine) is an antihistamine for allergies. Not sure why u need both, but please do talk to your doctor about this. ...Read more

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Is it safe to take claritan and Benadryl (diphenhydramine) together?

Yep!: They are both antihistamines, with a difference. Benedryl is sedating, has to be taken 3-4 times a day, and may need to be reserved for bedtime dosing. Claritin (loratadine) is a once-a-day, nonsedating antihistamine, and can be taken any time of day. One common technique for using combination antihistamines for severe symptoms would be morning Claritin (loratadine) and bedtime benedryl. ...Read more

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Is it safe to take Benadryl (diphenhydramine) and melatonin together?

Is it safe to take Benadryl (diphenhydramine) and melatonin together?

Sleep Better: I agree w dr. Labarbera. Although they can be used together - don't really recommend it. Benadryl (diphenhydramine) can lead to rebound insomnia. How about starting w good sleep hygiene. 1. Keep a regular bedtime & wakening time (to include weekends). Get up the same time each day, regardless of what time you fell asleep.
2. Make a regular, relaxing bedtime routine. Relaxing rituals prior to bedtime may include. ...Read more

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Is it safe to take loratadine and Benadryl (diphenhydramine) together?

Is it safe to take loratadine and Benadryl (diphenhydramine) together?

Depends: They are both in the same family (antihistamines), but a few people have daytime symptoms so take non-sedating med (like loratadine) and its effect wears off before next day's dose, so take a sedating (/older) antihistamine (like benadryl) at bedtime for continued relief and to aid with sleep. If no heart / urinary / blood pressure issues and no other meds to conflict with, not likely a problem. ...Read more

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What happens if child takes Benadryl (diphenhydramine) and allegra together?

What happens if child takes Benadryl (diphenhydramine) and allegra together?

Not much: They are both antihistamines and would reduce allergic symptoms. The Benadryl (diphenhydramine) might make him/her a bit sleepy. ...Read more

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Can I take Benadryl (diphenhydramine), valerian and melatonin together every day?

Can I take Benadryl (diphenhydramine), valerian and melatonin together every day?

Thoughts..: Valerian, has the possibility of causing some drowsiness, so I would be careful when taking that with benadryl, (diphenhydramine) which can also cause drowsiness. If someone's been taking it for a long time and they haven't had any significant reactions then it's probably okay. But like almost all the supplements out there, they haven't been rigorously tested for safety and interactions so it's buyer beware. ...Read more

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Can I take Allegra & Benadryl (diphenhydramine) together or one or the other? Thanks!

Can I take Allegra & Benadryl (diphenhydramine) together or one or the other? Thanks!

Better not together: One or the other, space them out if you have to take both, but under doctor's supervision ...Read more

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Is it dangerous to take valuim 20mg and Benadryl (diphenhydramine) 50mg together? I have high tolerence

I'd avoid it: Dangerous is different to different folk. I'd certainly hope you'd not drive or do anything requiring alertness, judgement, steadiness, etc. I would avoid it. But the medications you already list are already risky for those reasons in combination. Talk w/ your provider. Don't drive unless ABSOLUTELY unavoidable. Be careful. ...Read more

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The dr prescribed me tussonex for my cough...She also told me to get some sleep tonight to take a benadryl (diphenhydramine)....Is it ok to take together?

Yes but: Tussionex often makes one drowsy without anything else. I would suggest that you try tussionex alone for the first night before adding benadryl (diphenhydramine). At any rate, this should not be a long-term treatment. ...Read more

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Can I take 1 mg ativan and 25mg benadryl (diphenhydramine). Together and be fine like not die. There such low does it should be fine right? Just make me tired right?

Can I take 1 mg ativan and 25mg benadryl (diphenhydramine). Together and be fine like not die. There such low does it should be fine right? Just make me tired right?

Talk to your doctor: This combination of medication at the dose you mentioned is not fatal as long as you are not allergic to either medicine. They do have an additive sedating effect. You should not drive. Talk to the doctor who prescribed you this medication and only take your medicine as prescribed. ...Read more

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What would happen if someone takes a Benadryl (diphenhydramine) & 5mg vicdion together?

More sleepy: Nothing serious at these low doses although you may feel more sleepy since the sedation effects of ech medicine add up. But it should be fine after 12-18 hours. ...Read more

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Can I take Benadryl (diphenhydramine) and nyquil together?

You can, but: Not recommended due to drug interactions. Both drugs increase sedation and drowsiness. ...Read more

Benadryl (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


Dr. Latonya Brown-Puryear
258 Doctors shared insights

Montelukast (Definition)

Http://www. Nlm. Nih. Gov/medlineplus/druginfo/meds/a600014.html. ...Read more