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Doctor insights on: Can You Take Mucinex With An Antihistamine

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Should you take Mucinex (guaifenesin) and an antihistamine together?

Should you take Mucinex (guaifenesin) and an antihistamine together?

No harm: There is no contraindication in taking an antihistamine together with a mucolytic (breaks up mucus) like mucinex (guaifenesin). However, the most effective treatment for nasal allergies is nsasl cortisone type sprays. ...Read more

Dr. Paul Carter
643 Doctors shared insights

Antihistamine (Definition)

Sedating and non-sedating antihistamines prevent and treat allergic reactions, and are ...Read more


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Does mucinex help post nasal drip? I have taken oral antihistamines, masonry and Sudanese and I'm still having really bad post nasal drip as I sleep.

Does mucinex help post nasal drip? I have taken oral antihistamines, masonry and Sudanese and I'm still having really bad post nasal drip as I sleep.

Intranasal steroids: Studies show intranasal steroids are highly effective as monotherapy for allergic rhinitis and more effective than antihistamines but okay in combination.
If you have sinus pressure/cough you may need MD eval for possible acute bacterial rhinosinusitis as well. ...Read more

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I am treating acute bronchitis with mucinex (guaifenesin). Today my nose is very itchy but I read I should avoid antihistamines due to bronchitis. Any suggestions?

I am treating acute bronchitis with mucinex (guaifenesin). Today my nose is very itchy but I read I should avoid antihistamines due to bronchitis. Any suggestions?

Need antibiotics to: Acute bronchitis does not show up on x-ray. I put my patients on antibiotics and sometimes IV steriods depending if I am going to admit them or not and bronchodilators. Never heard that antihistamines should not be used in bronchitis. If your nose is very itchy, could be allergens in which case, you may benefit
from nasonex (mometasone). Mucinex will help loosen the phlegm. ...Read more

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Can I take a benadryl (diphenhydramine) & Mucinex night together?

Can I take a benadryl (diphenhydramine) & Mucinex night together?

Yes: Benadryl (diphenhydramine) will help you sleep and help with excess mucus production. Mucinex (guaifenesin) is called an expectorant as it helps thin and loosen mucus to make your cough more effective at clearing the mucus from your lungs. There should be no problem taking these two medications together. ...Read more

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I just took a mucinex. Will I be okay if I take Benadryl (diphenhydramine) as well?

I just took a mucinex. Will I be okay if I take Benadryl (diphenhydramine) as well?

Not a good idea: You have to know Mucinex help thin the phlegm and Benadryl (diphenhydramine) has drying effect on mucous or phlegm, so you are defeating the purpose of taking musinex
if you need to take antihistamine with Mucinex for allergy, I will recommend takind over the counter Claritin which may not be as drying as benadryl, (diphenhydramine) and don't forget to drink lot of fluids. ...Read more

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Can I take Mucinex dm and Benadryl (diphenhydramine) together?

Can I take Mucinex dm and Benadryl (diphenhydramine) together?

Medician Question: This combination could make you very sleepy so be careful - in some cases there could be serious consequenses. See your doctor for more definitive treatment of your cough. ...Read more

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Can I take mucinex D and benadryl (diphenhydramine)? I have taken mucinex D for a combination of a cold and allergies but just had an allergic reaction to a food.

Can I take mucinex D and benadryl (diphenhydramine)? I have taken mucinex D for a combination of a cold and allergies but just had an allergic reaction to a food.

Yes, but. . .: If any tongue or lip swelling, or difficulty breathing/swallowing, call 911 or local emergency services. Need to avoid allergen & carry EpiPen (epinephrine). www. Drugs. Com Interactions Checker says there's no interaction btwn Mucinex D (guaifenesin & pseudoephedrine) & Benadryl (diphenhydramine). However, only antihistamine like latter is useful for allergies. Former is combo of expectorant & decongestant. ...Read more

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Can you take Benadryl allergy with Mucinex Cold, Flu, & Sore Throat? Think I have a sinus infection.

Can you take Benadryl allergy with Mucinex Cold, Flu, & Sore Throat? Think I have a sinus infection.

Yes you can: But don't exceed recommended dose for either and read the labels carefully. Good that you asked, always exercise caution with multiple medications. If this combination doesn't work, you may need to see your doctor for assessment and possibly prescription medications, best wishes ...Read more

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Can you take Mucinex (guaifenesin) with an inhaler/anihistamine?

Can you take Mucinex (guaifenesin) with an inhaler/anihistamine?

Yes: No contraindications with combination sited. Guafenesin is in many products including Mucinex (guaifenesin) and many cough remedies. Just do not overdose with this medication. Can in very high blood levels cause slowing of heart. ...Read more

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Is it ok to mix guafisen (mucinex) with diphenhydramine (benadryl)?

Is it ok to mix guafisen (mucinex) with diphenhydramine (benadryl)?

Yes.: The mix without interaction, but do not take more benedryl than indicated for your age, size, and weight. ...Read more

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Is it okay to give 10 mL Of Children's mucinex with 10 mL of Benadryl (diphenhydramine) Allergy Plus to a 12 year old?

Is it okay to give 10 mL Of Children's mucinex with 10 mL of Benadryl (diphenhydramine) Allergy Plus to a 12 year old?

Yes: But benadryl (diphenhydramine) might make a child dopey or drowsy or overactive. It would not be my choice. You neglect to detail the symptoms. Best approach can be determined by knowledge of the details. ...Read more

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Is it ok to give my 5 year old children's benadryl and childrens mucinex cough? She has bad allergies which makes her cough mostly at night.

Is it ok to give my 5 year old children's benadryl and childrens mucinex cough? She has bad allergies which makes her cough mostly at night.

MGT: I would not advise giving these medications to your child based on the information provided.
I would suggest an over the counter anti histamine such as Claritin instead which is less sedating.
The underlying cause of her nighttime cough should be further evaluated by her PCP. Does she have a history of asthma? Is there smoke exposure? ...Read more

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When should you take an antihistamine?

Multiple reasons: Depending on the type of antihistamine used they can be used to treat things such as allergy symptoms, nausea, dizziness, motion sickness, anxiety, itching, and difficulty sleeping. ...Read more

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Is it ok to take antihistamines with?

With what?: If you are thinking about drinking alcohol, do not do it. Antihistamines might potentiate the effect of alcohol. ...Read more

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Can you take antihistamine with codeine?

Can you take antihistamine with codeine?

Yes: There is a medication called tussionex that combines an older antihistamine (chlorpheniramine) with hydrodocone (similar to codeine). This medication is especially effective for severe irritant cough. It is important to carefully follow dosing directions. ...Read more

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Is it safe to take an antihistamine daily?

Is it safe to take an antihistamine daily?

Yes but why: Although antihistamines are a very safe class of medications, the better question is why is there a need to take them daily? If antihistamines are being taken for treatment of nasal symptoms, see an allergist to identify the trigger. ...Read more

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Is it ok to take three different antihistamines?

Is it ok to take three different antihistamines?

Not a good idea: Unless specifically instructed by an allergist. I have only seen people on more than one antihistamine for severe recurrent hives (urticaria). Taking too many antihistamines at once can cause issues with urinary retention and other problems. ...Read more

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I am allergie to antihistamine, can I take pepid?

I am allergie to antihistamine, can I take pepid?

Describe allergy: Antihistamines are traditionally used to treat allergic reactions. I am curious as to what exactly what happens to you in response to specific antihistamines: benadryl, (diphenhydramine) zyrtec, Claritin etc.
Pepcid is a medication that inhibits acid production by the stomach and would be helpful for treatment of heartburn, indigestion (dyspepsia), gastitis (stomach inflammation) or reflux of acid ...Read more

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Can you tell me if I could take two antihistamines at once?

Yes but why: If you take two antihistamines at once you will bring out the less desirable side effects such as drowsiness and dry mouth. There is really no benefit from this and could lead to an overdose if you did this long term. Its best to take one at a time give it a few days to determine if that antihistamine is working and if not change to another. ...Read more

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Can you tell me how many antihistamines can you take per day?

Can you tell me how many antihistamines can you take per day?

Antihistamines: You should follow the prescription given to you or the maximum amount on the medication insert, do not self medicate. If higher doses are necessary, they should be guided by an experienced allergist. ...Read more

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Is it harmful if you take an antihistamine when it is not needed?

Probably not: Antihistamines are one of the safest classes of medications and have been available since the 1940s. At usual doses, there is very few side effects and no harm that will come from taking an antihistamine, especially the newer generation ones such as claritin, clarinex, zyrtec, xyzal (levocetirizine) or allegra. ...Read more

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Can I take antihistamine tabs with coderone tabs and ramipril capsules?

Can I take antihistamine tabs with coderone tabs and ramipril capsules?

Here are some...: Both Amiodarone and ramipril are used for irregular heart beat and high blood pressure, and antihistamine, theoretically, should not have direct adverse side effects with the above both drugs. But, as we age, our functional reserve declines so becoming more vulnerable to additive effects from multiple drug use. Hence, ask your doc first so to minimize unwanted side effects. ...Read more

Mucinex (Definition)

Guaifenesin is a cough suppressant which is a kind of antihistamine type drug (common ...Read more