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Doctor insights on: Can You Take Flexeril With Seroquel

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Can you take seroquel (quetiapine) with flexeril?

Can you take seroquel (quetiapine) with flexeril?

Ask your doctor: Many drugs have interactions with each other and that includes this combination. Both of these meds. Have a "sedative" like effect and the combination is at minimum additive. If you have been on one medication for some time than the second will likely be less prone to cause an issue than were you to start both at the same time. This is an issue that a professional should be actively managing. ...Read more

Dr. Heidi Fowler
431 doctors shared insights

Quetiapine (Definition)

Quetiapine (brand seroquel) is classified as an atypical antipsychotic medication. It is fda approved to treat schizophrenia, bipolar disorder, and as an adjunct with antidepressants in the treatment of major depressive disorder. Serious side effects include tardive dyskinesia, neuroleptic malignant syndrome, and metabolic syndrome with weight gain, risk of ...Read more


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I take 150mg of doxepin 600 seroquel (quetiapine) and 150mg of trazadone at night. Recently prescribed 30 mg flexeril and 100 mg tramadol. Is this safe?

Please ensure: That all providers who are prescribing medications for you are aware of all of your medications & supplements. This combination is likely to be very sedating. ...Read more

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My husband accidentally took 10mg of flexeril with 100mg of seroquel.... is he going to be ok or she he try to throw them up?

My husband accidentally took 10mg of flexeril with 100mg of seroquel.... is he going to be ok or she he try to throw them up?

Sleepy: It will probably cause him to be extra sleepy today(for 24 hours) but otherwise no great harm. He should avoid hazardous machinery and driving today. ...Read more

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Is it Ok to take zzzquil now if i took a flexeril at 2pm?

Is it  Ok to take zzzquil now if i took a flexeril at 2pm?

Seek advice: The 2 can interact with each other to cause a variety of side effects see below:
https://www.drugs.com/interactions-check.php?drug_list=758-386,896-16076

It depends what you were doing (might be risky if driving or operating heavy machinery for instance). Safest approach here is to seek advice from a doctor or pharmacist licensed in your area. ...Read more

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Can i take flexeril (cyclobenzaprine hcl) and Azo together?

Yes: Yes, there are no known significant drug interactions. ...Read more

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Is it ok to take 5 mg Flexeril with 50 mg Zoloft (sertraline)?

Is it ok to take 5 mg Flexeril with 50 mg Zoloft (sertraline)?

Although the doses: you are referring to aren't particularly high- combining these medications can increase risk for serotinergic syndrome. I have actually seen Serotonin Syndrome occur at moderate medication doses. ...Read more

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What is flexeril? Why take it with benadryl (diphenhydramine)?

What is flexeril? Why take it with benadryl (diphenhydramine)?

Flexeril@Benadryl: Flexeril is a muscle relaxant, its generic name is cyclobenzaprine, it does not have to be taken with Benadryl (diphenhydramine) to be effective.But it can be taken with benadryl, (diphenhydramine) but be careful, it will cause sedation. ...Read more

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Is it okay to take Benadryl (diphenhydramine) with a flexeril?

Should be ok: Benadry is an anti-allergy (anti-histamine) and Flexeril (cyclobenzaprine hcl) is essentially a serotonin anti-depressant med. But you might feel a little extra sleepy, so be careful about machinery/driving etc and try it out with some supervision the first time b/c everyone has individual reactions. ...Read more

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Can i take naproxan and flexeril (cyclobenzaprine hcl) together?

See below: There should be no interaction between Naproxen and flexeril (cyclobenzaprine hcl). I recommend that my patients do not drive or use machinary when taking Flexeril (cyclobenzaprine hcl) as drowsiness is a frequent side effect. ...Read more

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Can you safely take codeine with Flexeril (cyclobenzaprine hcl)?

Yes you can: Please be aware that taking codeine with Flexeril (cyclobenzaprine hcl) may enhance some of the side effects of codeine such as constipation and urine retention. In addition, taking these medications together may cause effects such as sedation and drowsiness. ...Read more

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Can I take Cyclobenzaprine (Flexeril) while on Paxil (paroxetine)?

Can I take Cyclobenzaprine (Flexeril) while on Paxil (paroxetine)?

Yes but: I would limit use of Flexeril to 1 week as chronic use can cause depression. This is what I was taught at USA medical center in Mobile. This is also what I have seen in 22 years of practice. Robaxin, Norflex (orphenadrine) and Skellaxin are less likely to cause depression. ...Read more

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Can I take a flexeril (cyclobenzaprine hcl) after taking an adavan?

Not a good idea.: Not if you are planning on driving or operating heavy machinery or have significant pulmonary issues like sleep apnea. Both can lead to drowsiness. You should also avoid drinking alcohol which is a depressant like ativan. Ativan can cause respiratory depression at higher doses like narcotics which could cause apnea and even death. Take the flexeril (cyclobenzaprine hcl) during the day. ...Read more

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Is it safe to take 5mg of flexeril with 30mg of cymbalta (duloxetine)?

Is it safe to take 5mg of flexeril with 30mg of cymbalta (duloxetine)?

You can do it!: They are safe used together. Would not take both at the same time, though! ...Read more

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How long does it take for the side effects of flexeril (cyclobenzaprine hcl) to go away?

Not sure: Usually as soon as you stop the medication. The side effects should be reduced and gone in the time it takes to leave your body - usually a few days. ...Read more

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Dr. Alan Ali
463 doctors shared insights

Seroquel (Definition)

Seroquel is a serotonin-dopamine receptor blocker which is a kind of atypical anti-psychotic drug (drug ...Read more


Dr. Syed H. Sajid
311 doctors shared insights

Cyclobenzaprine Hcl (Definition)

Cyclobenzaprine HCl is a muscle relaxant which is a ...Read more