Doctor insights on:
Can You Reverse Chronic Organ Rejection
Several factors: As more sophisticated anti-rejection meds became available, the incidence of acute rejection has decreased over the past 40 years. However, no matter how long you take your anti-rejection meds, your immune system (white blood cells) will know your own tissues/organs from transplants. If your body does not have enough anti-rejection meds that suppress your immune system, a rejection occurs. ...Read moreSee 1 more doctor answer
Not really: There is intense ongoing experimentation in this process called tolerance-universal acceptance of foreign tissue. Current approaches involve extensive manipulation of the immune system with drugs, radiation, antibodies, etc. That are hardly "natural." tolerance is the holy grail of organ transplantation. Not there yet. Only natural way would be with identical (same placenta) twins. ...Read moreSee 2 more doctor answers
Can be advantaged: Immediate family member can be less immunogenic to a person than strangers. However, the survival differences in organ transplants between unrelated and related individuals for similarly aged donors is small. The one exception are the 25% of siblings that share the same hla type, called hla identical. ...Read more
Innate and Adaptive: Innate or non-specific immunity involves the skin, lining of the GI tract, respiratory tract, gu tract, etc; and adaptive immunity that involves cells (primarily lymphocytes). Both types of immunity can affect the graft and trigger rejection. In addition, immune responses involve the formation of both cells and antibodies (proteins) that are reactive against the transplanted organ. ...Read moreSee 2 more doctor answers
Many steps.: Transplant recipients are monitored closely for rejection by testing the function of the transplanted organ with blood tests, certain imaging studies, and at times a biopsy of the graft the recipient is also responsible for taking their anti-rejection drugs and telling the transplant team promptly if there are changes in their condition. Education of the process is key. ...Read moreSee 2 more doctor answers
I saw on CNN a lady who received an organ transplant but it was altered before transplanting to avoid rejection, no drugs needed. How's that possible?
Trsplt- No immunosup: Please see the references below. Some protocols are developing to wean people off immunosupression which was unheard of before,I ma not sure if this is what you are referring to: http://www.aafp.org/afp/2008/0101/p65.html http://www.nejm.org/doi/full/10.1056/NEJMoa071074 Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):19054-8. doi: 10.1073/pnas.1317561110. Epub 2013 Oct 28 ...Read more
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