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Doctor insights on: Can You Reverse Chronic Organ Rejection

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Can you reverse chronic organ rejection?

No: You can delay the process but once you have the diagnosis of chronic rejection it is not reversible. ...Read more

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What causes organ rejection?

What causes organ rejection?

Several factors: As more sophisticated anti-rejection meds became available, the incidence of acute rejection has decreased over the past 40 years. However, no matter how long you take your anti-rejection meds, your immune system (white blood cells) will know your own tissues/organs from transplants. If your body does not have enough anti-rejection meds that suppress your immune system, a rejection occurs. ...Read more

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Is there any natural way to prevent organ rejection from occurring?

Is there any natural way to prevent organ rejection from occurring?

Not really: There is intense ongoing experimentation in this process called tolerance-universal acceptance of foreign tissue. Current approaches involve extensive manipulation of the immune system with drugs, radiation, antibodies, etc. That are hardly "natural." tolerance is the holy grail of organ transplantation. Not there yet. Only natural way would be with identical (same placenta) twins. ...Read more

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Are immediate family members better for organ donation in terms of rejection?

Are immediate family members better for organ donation in terms of rejection?

Can be advantaged: Immediate family member can be less immunogenic to a person than strangers. However, the survival differences in organ transplants between unrelated and related individuals for similarly aged donors is small. The one exception are the 25% of siblings that share the same hla type, called hla identical. ...Read more

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What part of the immune system is involved in organ rejection?

What part of the immune system is involved in organ rejection?

Innate and Adaptive: Innate or non-specific immunity involves the skin, lining of the GI tract, respiratory tract, gu tract, etc; and adaptive immunity that involves cells (primarily lymphocytes). Both types of immunity can affect the graft and trigger rejection. In addition, immune responses involve the formation of both cells and antibodies (proteins) that are reactive against the transplanted organ. ...Read more

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What steps are taken at the hospital after the operation to prevent organ rejection?

What steps are taken at the hospital after the operation to prevent organ rejection?

Many steps.: Transplant recipients are monitored closely for rejection by testing the function of the transplanted organ with blood tests, certain imaging studies, and at times a biopsy of the graft the recipient is also responsible for taking their anti-rejection drugs and telling the transplant team promptly if there are changes in their condition. Education of the process is key. ...Read more

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I saw on CNN a lady who received an organ transplant but it was altered before transplanting to avoid rejection, no drugs needed. How's that possible?

I saw on CNN a lady who received an organ transplant but it was altered before transplanting to avoid rejection, no drugs needed. How's that possible?

Trsplt- No immunosup: Please see the references below. Some protocols are developing to wean people off immunosupression which was unheard of before,I ma not sure if this is what you are referring to: http://www.aafp.org/afp/2008/0101/p65.html http://www.nejm.org/doi/full/10.1056/NEJMoa071074 Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):19054-8. doi: 10.1073/pnas.1317561110. Epub 2013 Oct 28 ...Read more

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What signs and symptoms indicate organ transplant rejection?

Depends on the organ: In general, acute rejection of any transplanted solid organ can cause fever, chills, tiredness, weakness, and poor appetite. Each specific organ may become tender and swollen, and the function of each would diminish. ...Read more

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Can rejection of an organ cause severe itching, my husband had his liver transplanted?

Can rejection of an organ cause severe itching, my husband had his liver transplanted?

Yes: Rejection itself does not cause itching. If the bilirubin is up during an episode of rejection it can irritate the skin and cause itching. ...Read more

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